Grantee Research Project Results
2011 Progress Report: Consortium for Manufactured Nanomaterial Bioavailability & Environmental Exposure
EPA Grant Number: R834575Title: Consortium for Manufactured Nanomaterial Bioavailability & Environmental Exposure
Investigators: Colvin, Vicki L. , Klaine, Stephen J. , Lead, Jamie , Luoma, Sam , Stone, Vicki , Tyler, Charles , Valsami-Jones, Eugenia , Chipman, Kevin , Viant, Mark , Fernandes, Teresa
Current Investigators: Lead, Jamie , Alvarez, Pedro J. , Colvin, Vicki L. , Klaine, Stephen J. , Luoma, Sam , Stone, Vicki , Tyler, Charles , Valsami-Jones, Eugenia , Chipman, Kevin , Viant, Mark , Fernandes, Teresa
Institution: Rice University , Clemson University , University of California - Davis , University of Exeter , University of Birmingham , Edinburgh Napier University , Natural History Museum (London)
EPA Project Officer: Aja, Hayley
Project Period: August 1, 2010 through August 1, 2013 (Extended to December 31, 2015)
Project Period Covered by this Report: August 1, 2010 through August 1,2011
Project Amount: $2,000,000
RFA: Environmental Behavior, Bioavailability and Effects of Manufactured Nanomaterials - Joint US – UK Research Program (2009) RFA Text | Recipients Lists
Research Category: Chemical Safety for Sustainability
Objective:
Figure 1. Reseach in the nanoBEE consortium
Progress Summary:
- Acute toxicity for a range of NP types quantified
- Dissolution, toxicity and other behaviour are strongly dependent on surface chemistry, including the nature of the capping agent
- Maternal transfer in fish of Ag NPs
- Ag NPs are bioavailable
- Toxicity at least partly due to dissolution
Future Activities:
The future activities will follow the expected progress plan developed initially for this project. The following activities will be the focus of Year 2 (2011-2012):
- Synthesise different NPs, including isotopically labelled ones (Years 2-3)
- Develop cryo STEM tomography with fiducial markers (Year 2)
- Apply isotopically labelled NPs to allow low exposure concentrations to be used (Years 2-4)
- Investigate maternal transfer (Years 2-3)
- Investigate NP effects on bacterial biogeochemical services (Years 2-4)
- Investigate molecular responses to fully determine mechanisms pof action in Daphnia (Years 2-3)
Throughout this second year, knowledge exchange will continue through relevant conferences and publications as well as wide interactions with relevant stakeholders both formally and informally.
In addition, the close links established during the first year between all partners will continue. For instance, Rice, NHM, and Birmingham have all linked with partners to provide relevant NPs, and UC Davis, USGS, and Clemson have all discussed appropriate model parameters for ecotoxicology exposures with other partners.
Journal Articles on this Report : 2 Displayed | Download in RIS Format
Other project views: | All 37 publications | 37 publications in selected types | All 35 journal articles |
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Type | Citation | ||
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Fabrega J, Luoma SN, Tyler CR, Galloway TS, Lead JR. Silver nanoparticles: behaviour and effects in the aquatic environment. Environment International 2011;37(2):517-531. |
R834575 (2011) R834575 (Final) |
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Xiu Z-M, Ma J, Alvarez PJJ. Differential effect of common ligands and molecular oxygen on antimicrobial activity of silver nanoparticles versus silver ions. Environmental Science & Technology 2011;45(20):9003-9008. |
R834575 (2011) R834575 (2013) R834575 (Final) |
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Supplemental Keywords:
nanotechnology, nanoscience, bioavailability, emerging contaminants, environmental modeling, manufactured nanoparticles, biotic ligand model, biodynamic model, environmental exposure modelProgress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.