Grantee Research Project Results
UC Davis Center for Children’s Environmental Health
EPA Grant Number: R833292Center: UC Davis Center for Children's Environmental Health and Disease Prevention
Center Director: Van de Water, Judith
Title: UC Davis Center for Children’s Environmental Health
Investigators: Pessah, Isaac N.
Current Investigators: Pessah, Isaac N. , Berman, Robert F. , Bennett, Deborah H. , Golub, Mari S. , Walker, Cheryl , Hertz-Picciotto, Irva , Van de Water, Judith , Ashwood, Paul , Hansen, Robin , Ozonoff, Sally
Institution: University of California - Davis
EPA Project Officer: Hahn, Intaek
Project Period: November 1, 2006 through October 31, 2011 (Extended to October 31, 2013)
Project Amount: $3,782,733
RFA: Centers for Children’s Environmental Health and Disease Prevention Research (2005) RFA Text | Recipients Lists
Research Category: Children's Health , Human Health
Objective:
The principal concern of the UC Davis Center for Children’s Environmental Health (CCEH) is to identify and understand environmental, immunologic, and genetic risk factors contributing to the incidence and severity of childhood autism. Autism is a heterogeneous neurodevelopmental disorder defined by core deficits in social reciprocity, communication, and restrictive/repetitive patterns of interest and behavior. Generally accepted estimates of prevalence range from 1:750 for the narrowest diagnostic criteria, to 1:166 for autism spectrum disorder (ASD). The California Department of Developmental Services records on average approximately 700-750 autism diagnoses each quarter. Although autism may be one of the most heritable complex disorders, the defective genes conferring autism risk do not segregate in a simple Mendelian manner. The prevalence of autism is approximately four times higher in males than in females. Results from over ten genome-wide autism screens indicate that potential susceptibility genes are spread across the entire genome. Estimates of the number of genes involved in autism range from 3-10 to 15 and up to 100. However no single locus alone appears to be sufficient to cause the full clinical phenotype. Evaluation of a broader autistic phenotype that included communication and social disorders increased concordance from 60% to 92% in monozygotic twins and from 0% to 10% in dizygotic pairs. These results indicate that interactions among multiple genes are likely to contribute to autism, and that epigenetic factors and exposure to environmental modifiers may contribute significantly to variable expression of autism, and autism-related traits.
The mission of the CCEH is to promote daily interactions among a multidisciplinary team of scientists whose main research interest is to understand the complex web of etiologic factors that contribute to autism. The shared philosophy among Center participants is that a better understanding of the immunological and neurobiological mechanisms associated with this neurodevelopmental disorder can not only lead to a better understanding of the mechanisms that influence it but can also accelerate the discovery of effective intervention strategies.
Approach:
Since it is generally accepted that the earlier an intervention is begun in autistic children, the greater the chances of improvement, an intervention that can be implemented before symptoms have fully manifested should have the strongest impact in reducing severity and potentially even preventing some cases. Thus, early markers of risk are needed to identify children who are at risk. These may include behavioral, environmental, physiologic, biochemical, and genomic markers, and those based on morphological and neuroimaging parameters.
Expected Results:
The goals of the CCEH in the next five years are to: (1) better understand the mechanisms by which environmental, immunologic, and molecular factors interact to influence the risk and severity of autism; (2) identify early immunologic, environmental, and genomic markers of susceptibility to autism; (3) develop mouse models of immunologic susceptibility to environmental triggers and define the impact of these triggers on the development of complex behaviors, key brain structures and neurotransmitter receptors relevant to autism (4) translate our research findings into diagnostic tools that can be used in clinical practice to predict early autism risk; and (5) supply the community with accurate and timely information about autism risk factors.
Journal Articles: 293 Displayed | Download in RIS Format
Other center views: | All 494 publications | 305 publications in selected types | All 293 journal articles |
---|
Type | Citation | ||
---|---|---|---|
|
Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kultz D, Chang DPY, Gee SJ, Hammock BD. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environmental Health Perspectives 2008;116(9):1203-1210. |
R833292 (2009) R833292 (Final) R829388 (Final) |
|
|
Ahn KC, Gee SJ, Tsai H-J, Bennett D, Nishioka MG, Blum A, Fishman E, Hammock BD. Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47. Environmental Science & Technology 2009;43(20):7784-7790. |
R833292 (Final) |
Exit |
|
Ahn KC, Kim H-J, McCoy MR, Gee SJ, Hammock BD. Immunoassays and biosensors for monitoring environmental and human exposure to pyrethroid insecticides. Journal of Agricultural and Food Chemistry 2011;59(7):2792-2802. |
R833292 (Final) |
Exit |
|
Ahn KC, Gee SJ, Kim H-J, Aronov PA, Vega H, Krieger RI, Hammock BD. Immunochemical analysis of 3-phenoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides. Analytical and Bioanalytical Chemistry 2011;401(4):1285-1293. |
R833292 (Final) |
Exit |
|
Ahn KC, Kasagami T, Tsai H-J, Schebb NH, Gee SJ, Hammock BD. An immunoassay to evaluate human/environmental exposure to the antimicrobial triclocarban. Environmental Science & Technology 2012;46(1):374-381. |
R833292 (Final) |
Exit |
|
Anderson PJ, Lango J, Carkeet C, Britten A, Krautler B, Hammock BD, Roth JR. One pathway can incorporate either adenine or dimethylbenzimidazole as an α-axial ligand of B12 cofactors in Salmonella enterica. Journal of Bacteriology 2008;190(4):1160-1171. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Angkustsiri K, Krakowiak P, Moghaddam B, Wardinsky T, Gardner J, Kalamkarian N, Hertz-Picciotto I, Hansen RL. Minor physical anomalies in children with autism spectrum disorders. Autism 2011;15(6):746-760. |
R833292 (2011) R833292 (Final) |
Exit |
|
Aronov PA, Hall LM , Dettmer K, Stephensen CB, Hammock BD. Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry 2008;391(5):1917-1930. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Ashwood P, Kwong C, Hansen R, Hertz-Picciotto I, Croen L, Krakowiak P, Walker W, Pessah IN, Van de Water J. Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype? Journal of Autism and Developmental Disorders 2008;38(1):169-175. |
R833292 (2007) R833292 (2008) R833292 (2009) R833292 (Final) R829388 (2006) R829388 (2007) R829388 (Final) |
Exit |
|
Ashwood P, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen RL, Croen LA, Ozonoff S, Pessah IN, Van de Water J. Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes. Journal of Neuroimmunology 2008;204(1-2):149-153. |
R833292 (2009) R833292 (Final) |
Exit |
|
Ashwood P, Schauer J, Pessah IN, Van de Water JV. Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. Journal of Neuroimmunology 2009;208(1-2):130-135. |
R833292 (2009) R833292 (Final) |
Exit |
|
Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J. Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain, Behavior, and Immunity 2011;25(1):40-45. |
R833292 (2010) R833292 (Final) |
Exit Exit Exit |
|
Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Altered T cell responses in children with autism. Brain, Behavior, and Immunity 2011;25(5):840-849. |
R833292 (2010) R833292 (Final) |
Exit Exit Exit |
|
Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders. Journal of Neuroimmunology 2011;232(1-2):196-199. |
R833292 (2011) R833292 (Final) |
Exit |
|
Bannister RA, Pessah IN, Beam KG. The skeletal L-type Ca2+ current is a major contributor to excitation-coupled Ca2+ entry. Journal of General Physiology 2009;133(1):79-91. |
R833292 (2009) R833292 (Final) |
Exit Exit |
|
Barile D, Marotta M, Chu C, Mehra R, Grimm R, Lebrilla CB, German JB. Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry. Journal of Dairy Science 2010;93(9):3940-3949. |
R833292 (Final) |
Exit Exit Exit |
|
Baron CA, Tepper CG, Liu SY, Davis RR, Wang NJ, Schanen NC, Gregg JP. Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes. Human Molecular Genetics 2006;15(6):853-869. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Baron CA, Liu SY, Hicks C, Gregg JP. Utilization of lymphoblastoid cell lines as a system for the molecular modeling of autism. Journal of Autism and Developmental Disorders 2006;36(8):973-982. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit |
|
Barrientos G, Bose DD, Feng W, Padilla I, Pessah IN. The Na+/Ca2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate (KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels. Molecular Pharmacology 2009;76(3):560-568. |
R833292 (2009) R833292 (Final) |
Exit Exit |
|
Bauman MD, Lavenex P, Mason WA, Capitanio JP, Amaral DG. The development of social behavior following neonatal amygdala lesions in rhesus monkeys. Journal of Cognitive Neuroscience 2004;16(8):1388-1411. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit |
|
Bennett DH, Wu XM, Teague CH, Lee K, Cassady DL, Ritz B, Hertz-Picciotto I. Passive sampling methods to determine household and personal care product use. Journal of Exposure Science & Environmental Epidemiology 2012;22(2):148-160. |
R833292 (2012) R831540 (Final) |
Exit |
|
Bennett D, Calafat A, Hertz-Piccioltto I, Shin H, Tancredi D. Modeled prenatal exposure to per-and polyfluoroalkyl substances in association with child autism spectrum disorder:A case-control study. Enviornmenal Research 2020;186(109514). |
R833292 (Final) R835432 (Final) |
Exit Exit |
|
Berman RF, Pessah IN, Mouton PR, Mav D, Harry J. Low-level neonatal thimerosal exposure: further evaluation of altered neurotoxic potential in SJL mice. Toxicological Sciences 2008;101(2):294-309. |
R833292 (2008) R833292 (2009) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Berman RF, Pessah IN, Mouton PR, Mav D, Harry GJ. Modeling neonatal thimerosal exposure in mice. Toxicological Sciences 2008;103(2):416. |
R833292 (2008) R833292 (Final) R829388 (Final) |
Exit Exit |
|
Braunschweig D, Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Autism: maternally derived antibodies specific for fetal brain proteins. NeuroToxicology 2008;29(2):226-231. |
R833292 (2007) R833292 (2008) R833292 (2009) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Braunschweig D, Duncanson P, Boyce R, Hansen R, Ashwood P, Pessah IN, Hertz-Picciotto I, Van de Water J. Behavioral correlates of maternal antibody status among children with autism. Journal of Autism and Developmental Disorders 2012;42(7):1435-1445. |
R833292 (2011) R833292 (Final) |
Exit |
|
Breen M, Garg P, Tang L, Mendonca D, Levy T, Barbosa M, Arnett A, Kurtz-Nelson E, Agolini E, Battaglia A. Episignatures Stratifying Helsmoortel-Van Der Aa Syndrome Show Modest Correlation with Phenotype. American Journal of Human Genetics 2020;107(3):555-563 |
R833292 (Final) |
Exit |
|
Bu B, Ashwood P, Harvey D, King IB, Water JV, Jin LW. Fatty acid compositions of red blood cell phospholipids in children with autism. Prostaglandins, Leukotrienes and Essential Fatty Acids 2006;74(4):215-221. |
R833292 (2007) R833292 (Final) R829388 (Final) |
Exit |
|
Buchen L. Scientists and autism: when geeks meet. Nature 2011;479(7371):25-27. |
R833292 (2012) |
Exit Exit |
|
Buck Louis GM, Gray LE Jr, Marcus M, Ojeda SR, Pescovitz OH, Witchel SF, Sippell W, Abbott DH, Soto A, Tyl RW, Bourguignon JP, Skakkebaek NE, Swan SH, Golub MS, Wabitsch M, Toppari J, Euling SY. Environmental factors and puberty timing: expert panel research needs. Pediatrics 2008;121(Suppl 3):S192-S207. |
R833292 (2009) R833292 (Final) |
Exit Exit Exit |
|
Buie T, Campbell DB, Fuchs III GJ, Furuta GT, Levy J, Van de Water J, Whitaker AH, Atkins D, Bauman ML, Beaudet AL, Carr EG, Gershon MD, Hyman SL, Jirapinyo P, Jyonouchi H, Kooros K, Kushak R, Levitt P, Levy SE, Lewis JD, Murray KF, Natowicz MR, Sabra A, Wershil BK, Weston SC, Zeltzer L, Winter H. Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report. Pediatrics 2010;125(Suppl 1):S1-S18. |
R833292 (Final) |
Exit Exit Exit |
|
Burke K, Cheng Y, Li B, Petrov A, Joshi P, Berman RF, Reuhl KR, DiCicco-Bloom E. Methylmercury elicits rapid inhibition of cell proliferation in the developing brain and decreases cell cycle regulator, cyclin E. NeuroToxicology 2006;27(6):970-981. |
R833292 (2009) R833292 (Final) R829388 (2006) R829388 (Final) R829388C005 (2005) R829391 (2006) |
Exit Exit Exit |
|
Cabanlit M, Maitland D, Wilson T, Simon S, Wun T, Gershwin ME, Van de Water J. Polyurethane shape-memory polymers demonstrate functional biocompatibility in vitro. Macromolecular Bioscience 2007;7(1):48-55. |
R833292 (2007) R833292 (Final) |
Exit Exit |
|
Cabanlit M, Wills S, Goines P, Ashwood P, Van de Water J. Brain-specific utoantibodies in the plasma of subjects with autistic spectrum disorder. Annals of the New York Academy of Sciences 2007;1107:92-103. |
R833292 (2007) R833292 (Final) |
Exit |
|
California Dental Association Foundation, American College of Obstetricians and Gynecologists District IX. Oral health during pregnancy and early childhood: evidence-based guidelines for health professionals. Journal of the California Dental Association 2010;38(6):391-403, 405-440. |
R833292 (2010) R833292 (Final) |
Exit |
|
Campbell MA, Golub MS, Iyer P, Kaufman FL, Li LH, Moran Messen F, Morgan JE, Donald JM. Reduced water intake: implications for rodent developmental and reproductive toxicity studies. Birth Defects Research Part B: Developmental and Reproductive Toxicology 2009;86(3):157-175. |
R833292 (2009) R833292 (Final) |
Exit |
|
Cao Z, Hammock BD, McCoy M, Rogawski M, Lein PJ, Pessah IN. Tetramethylenedisulfotetramine alters Ca2+ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABAA receptor-positive modulation. Toxicological Sciences 2012;130(2):362-372. |
R833292 (2012) |
Exit Exit Exit |
|
Careaga M, Van de Water J, Ashwood P. Immune dysfunction in autism: a pathway to treatment. Neurotherapeutics 2010;7(3):283-292. |
R833292 (2011) R833292 (Final) |
Exit Exit |
|
Carkeet C, Dueker SR, Lango J, Buchholz BA, Miller JW, Green R, Hammock BD, Roth JR, Anderson PJ. Human vitamin B12 absorption measurement by accelerator mass spectrometry using specifically labeled 14C-cobalamin. Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):5694-5699. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Chaidez V, Hansen RL, Hertz-Picciotto I. Autism spectrum disorders in Hispanics and non-Hispanics. Autism: The International Journal of Research and Practice 2012;16(4):381-397. |
R833292 (2012) R833292 (Final) |
Exit Exit |
|
Chelu MG, Goonasekera SA, Durham WJ, Tang W, Lueck JD, Riehl J, Pessah IN, Zhang P, Bhattacharjee MB, Dirksen RT, Hamilton SL. Heat-and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse. FASEB Journal 2006;20(2):329-330. |
R833292 (2007) R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit |
|
Chen X, Lin Y; Dang K, Puschner B. Quantification of Polychlorinated Biphenyls and Polybrominated Diphenyl Ethers in Commercial Cows’ Milk from California by Gas Chromatography--Triple Quadruple Mass Spectrometry. <PLosOne 2017;12(1):e0170129. |
R833292 (Final) R829388 (Final) R835432 (2016) R835432 (Final) |
Exit Exit |
|
Chen Y, Tassone F, Berman RF, Hagerman PJ, Hagerman RJ, Willemsen R, Pessah IN. Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration. Human Molecular Genetics 2010;19(1):196-208. |
R833292 (Final) |
Exit Exit Exit |
|
Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proceedings of the National Academy of Sciences of the United States of America 2012;109(35):14158-14163. |
R833292 (2012) R835432 (2013) |
Exit Exit Exit |
|
Chichlowski M, German JB, Lebrilla CB, Mills DA. The influence of milk oligosaccharides on microbiota of infants: opportunities for formulas. Annual Review of Food Science and Technology 2011;2:331-351. |
R833292 (2012) R833292 (Final) |
Exit Exit |
|
Coury DL, Ashwood P, Fasano A, Fuchs G, Geraghty M, Kaul A, Mawe G, Patterson P, Jones NE. Gastrointestinal conditions in children with autism spectrum disorder: developing a research agenda. Pediatrics 2012;130(Suppl 2):S160-S168. |
R833292 (2012) |
Exit Exit Exit Exit |
|
Croen LA, Goines P, Braunschweig D, Yolken R, Yoshida CK, Grether JK, Fireman B, Kharrazi M, Hansen RL, Van de Water J. Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) Study. Autism Research 2008;1(2):130-137. |
R833292 (2008) R833292 (Final) |
Exit Exit |
|
Croen LA, Braunschweig D, Haapanen L, Yoshida CK, Fireman B, Grether JK, Kharrazi M, Hansen RL, Ashwood P, Van de Water J. Maternal mid-pregnancy autoantibodies to fetal brain protein: the Early Markers for Autism Study. Biological Psychiatry 2008;64(7):583-588. |
R833292 (2008) R833292 (Final) |
Exit |
|
Crofton KM, Mundy WR, Lein PJ, Bal-Price A, Coecke S, Coecke S, Seiler AEM, Knaut H, Buzanska L, Goldberg A. Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals. ALTEX 2011;28(1):9-15. |
R833292 (2012) |
Exit Exit |
|
Dai JJ, Lieu L, Rocke D. Dimension reduction for classification with gene expression microarray data. Statistical Applications in Genetics and Molecular Biology 2006;5(1):Article 6 (19 pp.). |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit |
|
Dallas DC, Martin WF, Strum JS, Zivkovic AM, Smilowitz JT, Underwood MA, Affolter M, Lebrilla CB, German JB. N-linked glycan profiling of mature human milk by high-performance microfluidic chip liquid chromatography time-of-flight tandem mass spectrometry. Journal of Agricultural and Food Chemistry 2011;59(8):4255-4263. |
R833292 (2012) R833292 (Final) |
Exit |
|
Davis BB, Morisseau C, Newman JW, Pedersen TL, Hammock BD, Weiss RH. Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition. Journal of Pharmacology and Experimental Therapeutics 2006;316(2):815-821. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Denning L, Anderson JA, Davis R, Gregg JP, Kuzdenyi J, Maselli RA. High throughput genetic analysis of congenital myasthenic syndromes using resequencing microarrays. PLoS One 2007;2(9):e918. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Dettmer K, Hanna D, Whetstone P, Hansen R, Hammock BD. Autism and urinary exogenous neuropeptides: development of an on-line SPE-HPLC-tandem mass spectrometry method to test the opioid excess theory. Analytical and Bioanalytical Chemistry 2007;388(8):1643-1651. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Dettmer K, Aronov PA, Hammock BD. Mass spectrometry-based metabolomics. Mass Spectrometry Reviews 2007;26(1):51-78. |
R833292 (Final) R829388 (Final) |
Exit |
|
Diep AA, Hunsaker MR, Kwock R, Kim K, Willemsen R, Berman RF. Female CGG knock-in mice modeling the fragile X premutation are impaired on a skilled forelimb reaching task. Neurobiology of Learning and Memory 2012;97(2):229-234. |
R833292 (2012) |
Exit |
|
Dodds ED, German JB, Lebrilla CB. Enabling MALDI-FTICR-MS/MS for high-performance proteomics through combination of infrared and collisional activation. Analytical Chemistry 2007;79(24):9547-9556. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Dou J, Middleton L, Zhu Y, Benke K, Feinberg J, Croen L, Hertz-Picciotto I, Newschaffer C, LaSalle J, Fallin D. Development of a screening protocol to identify persons who are responsive to wood smoke particle-induced airway inflammation with pilot assessment of GSTM1 genotype and asthma status as response modifiers. INHALATION TOXICOLOGY 2022;15(1):28. |
R833292 (Final) |
Exit Exit |
|
Du XL, Tang Y, Xu H, Lit L, Walker W, Ashwood P, Gregg JP, Sharp FR. Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome. Genomics 2006;87(6):693-703. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD. Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proceedings of the National Academy of Sciences of the United States of America 2012;109(20):7923-7928. |
R833292 (2012) |
Exit Exit Exit |
|
Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen RL, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P. Altered gene expression and function of peripheral blood natural killer cells in children with autism. Brain, Behavior, and Immunity 2009:23(1):124-133. |
R833292 (2009) R833292 (Final) |
Exit Exit Exit |
|
Enstrom AM, Van de Water JA, Ashwood P. Autoimmunity in autism. Current Opinion in Investigational Drugs 2009;10(5):463-473. |
R833292 (Final) |
Exit |
|
Enstrom AM, Onore CE, Van de Water JA, Ashwood P. Differential monocyte responses to TLR ligands in children with autism spectrum disorders. Brain, Behavior, and Immunity 2010;24(1):64-71. |
R833292 (2009) R833292 (Final) |
Exit Exit Exit |
|
Enstrom A, Onore C, Hertz-Picciotto I, Hansen R, Croen L, Van de Water J, Ashwood P. Detection of IL-17 and IL-23 in plasma samples of children with autism. American Journal of Biochemistry and Biotechnology 2008;4(2):114-120. |
R833292 (2007) R833292 (2008) R833292 (2009) R833292 (Final) R829388 (2007) R829388 (Final) |
Exit Exit |
|
Enstrom A, Onore C, Tarver A, Hertz-Picciotto I, Hansen R, Croen L, Van de Water J, Ashwood P. Peripheral blood leukocyte production of BDNF following mitogen stimulation in early onset and regressive autism. American Journal of Biochemistry and Biotechnology 2008;4(2):121-129. |
R833292 (2007) R833292 (2008) R833292 (2009) R833292 (Final) R829388 (2007) R829388 (Final) |
Exit Exit |
|
Enstrom A, Krakowiak P, Onore C, Pessah IN, Hertz-Picciotto I, Hansen RL, Van de Water JA, Ashwood P. Increased IgG4 levels in children with autism disorder. Brain, Behavior, and Immunity 2009;23(3):389-395. |
R833292 (2009) R833292 (Final) |
Exit Exit Exit |
|
Esteve E, Smida-Rezgui S, Sarkozi S, Szegedi C, Regaya I, Chen L, Altafaj X, Rochat H, Allen P, Pessah IN, Marty I, Sabatier JM, Jona I, De Waard M, Ronjat M. Critical amino acid residues determine the binding affinity and the Ca2+ release efficacy of maurocalcine in skeletal muscle cells. Journal of Biological Chemistry 2003;278(39):37822-37831. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Fang X, Hu S, Watanabe T, Weintraub NL, Snyder GD, Yao J, Liu Y, Shyy JY-J, Hammock BD, Spector AA. Activation of peroxisome proliferator-activated receptor α by substituted urea-derived soluble epoxide hydrolase inhibitors. Journal of Pharmacology and Experimental Therapeutics 2005;314(1):260-270. |
R833292 (Final) R829388 (2006) R829388 (Final) R829389 (Final) |
Exit Exit Exit |
|
Feng W, Tu J, Pouliquin P, Cabrales E, Shen X, Dulhunty A, Worley PF, Allen PD, Pessah IN. Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1. Cell Calcium 2008;43(3):307-314. |
R833292 (2007) R833292 (Final) R829388 (Final) |
Exit |
|
Feng W, Barrientos GC, Cherednichenko G, Yang T, Padilla IT, Truong K, Allen PD, Lopez JR, Pessah IN. Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice. Molecular Pharmacology 2011;79(3):420-431. |
R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Froehlich JW, Dodds ED, Barboza M, McJimpsey EL, Seipert RR, Francis J, An HJ, Freeman S, German JB, Lebrilla CB. Glycoprotein expression in human milk during lactation. Journal of Agricultural and Food Chemistry 2010;58(10):6440-6448. |
R833292 (Final) |
Exit |
|
German JB, Smilowitz JT, Zivkovic AM. Lipoproteins: when size really matters. Current Opinion in Colloid & Interface Science 2006;11(2-3):171-183. |
R833292 (Final) |
Exit |
|
German JB, Gillies LA, Smilowitz JT, Zivkovic AM, Watkins SM. Lipidomics and lipid profiling in metabolomics. Current Opinion in Lipidology 2007;18(1):66-71. |
R833292 (Final) R829388 (Final) |
Exit |
|
German JB. Dietary lipids from an evolutionary perspective: sources, structures and functions. Maternal & Child Nutrition 2011;7(Suppl 2):2-16. |
R833292 (2012) R833292 (Final) |
Exit |
|
German JB, Zivkovic AM, Dallas DC, Smilowitz JT. Nutrigenomics and personalized diets: what will they mean for food? Annual Review of Food Science and Technology 2011;2:97-123. |
R833292 (2012) R833292 (Final) |
Exit |
|
Gibney MJ, Walsh M, Brennan L, Roche HM, German B, van Ommen B. Metabolomics in human nutrition: opportunities and challenges. American Journal of Clinical Nutrition 2005;82(3):497-503. |
R833292 (Final) R829388 (2006) R829388 (Final) R829388C001 (2005) |
Exit Exit Exit |
|
Giulivi C, Zhang Y-F, Omanska-Klusek A, Ross-Inta C, Wong S, Hertz-Picciotto I, Tassone F, Pessah IN. Mitochondrial dysfunction in autism. JAMA-Journal of the American Medical Association 2010;304(21):2389-2396. |
R833292 (2012) R833292 (Final) |
Exit Exit |
|
Giulivi C, Ross-Inta C, Omanska-Klusek A, Napoli E, Sakaguchi D, Barrientos G, Allen PD, Pessah IN. Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice. Journal of Biological Chemistry 2011;286(1):99-113. |
R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Goines PE, Croen LA, Braunschweig D, Yoshida, CK, Grether J, Hansen R, Kharrazi M, Ashwood P, Van de Water J. Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: a case-control study. Molecular Autism 2011;2:13. |
R833292 (2011) R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Goines P, Schauer J, Heuer L, Ashwood P, Van de Water J. Beta-2-microglobulin in autism spectrum disorders. American Journal of Biochemistry and Biotechnology 2007;3(2):87-91. |
R833292 (2007) R833292 (Final) R829388 (Final) |
Exit Exit |
|
Goines P, Van de Water J. The immune system's role in the biology of autism. Current Opinion in Neurology 2010;23(2):111-117. |
R833292 (2009) R833292 (Final) |
Exit |
|
Goines P, Haapanen L, Boyce R, Duncanson P, Braunschweig D, Delwiche L, Hansen R, Hertz-Picciotto I, Ashwood P, Van de Water J. Autoantibodies to cerebellum in children with autism associate with behavior. Brain, Behavior, and Immunity 2011;25(3):514-523. |
R833292 (2011) R833292 (Final) |
Exit Exit Exit |
|
Goth SR, Chu RA, Pessah IN. Oxygen tension regulates the in vitro maturation of GM-CSF expanded murine bone marrow dendritic cells by modulating class II MHC expression. Journal of Immunological Methods 2006;308(1-2):179-191. |
R833292 (2007) R833292 (2009) R833292 (Final) R829388 (2006) R829388 (Final) R829388C006 (2005) |
Exit Exit |
|
Goth SR, Chu RA, Gregg JP, Cherednichenko G, Pessah IN. Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal. Environmental Health Perspectives 2006;114(7):1083-1091. |
R833292 (2007) R833292 (Final) R829388 (2006) R829388 (Final) R829388C006 (2005) |
|
|
Greco CM, Navarro CS, Hunsaker MR, Maezawa I, Shuler JF, Tassone F, Delany M, Au JW, Berman RF, Jin L-W, Schumann C, Hagerman PJ, Hagerman RJ. Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome. Molecular Autism 2011;2(1):2 (13 pp.). |
R833292 (2012) |
Exit Exit Exit |
|
Gregg JP, Lit L, Baron CA, Hertz-Picciotto I, Walker W, Davis RA, Croen LA, Ozonoff S, Hansen R, Pessah IN, Sharp FR. Gene expression changes in children with autism. Genomics 2008;91(1):22-29. |
R833292 (2008) R833292 (2009) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Hall LM, Kimlin MG, Aronov PA, Hammock BD, Slusser JR, Woodhouse LR, Stephensen CB. Vitamin D intake needed to maintain target serum 25-hydroxyvitamin D concentrations in participants with low sun exposure and dark skin pigmentation is substantially higher than current recommendations. Journal of Nutrition 2010;140(3):542-550. |
R833292 (Final) |
Exit Exit Exit |
|
Halladay AK, Amaral D, Aschner M, Bolivar VJ, Bowman A, DiCicco-Bloom E, Hyman SL, Keller F, Lein P, Pessah I, Restifo L, Threadgill DW. Animal models of autism spectrum disorders: information for neurotoxicologists. NeuroToxicology 2009;30(5):811-821. |
R833292 (Final) |
Exit Exit Exit |
|
Hansen RL, Ozonoff S, Krakowiak P, Angkustsiri K, Jones C, Deprey LJ, Le D-N, Croen LA, Hertz-Picciotto I. Regression in autism: prevalence and associated factors in the CHARGE Study. Ambulatory Pediatrics 2008;8(1):25-31. |
R833292 (2008) R833292 (2009) R833292 (Final) R829388 (2007) R829388 (Final) |
Exit Exit |
|
Hart L, Thigpen A, Willits N, Lyons L, Hertz-Picciotto I, Hart B. Affectionate Interactions of Cats with Children Having Autism Spectrum Disorder. FRONTIERS IN VETERINARY SCIENCE 2018;5(39). |
R833292 (Final) R829388 (Final) R835432 (Final) |
Exit |
|
Herr CE, Dostal M, Ghosh R, Ashwood P, Lipsett M, Pinkerton KE, Sram R, Hertz-Picciotto I. Air pollution exposure during critical time periods in gestation and alterations in cord blood lymphocyte distribution: a cohort of livebirths. Environmental Health 2010;9:46. |
R833292 (2010) R833292 (Final) |
Exit Exit |
|
Herr CEW, Ghosh R, Dostal M, Skokanova V, Ashwood P, Lipsett M, Joad JP, Pinkerton KE, Yap P-S, Frost JD, Sram R, Hertz-Picciotto I. Exposure to air pollution in critical prenatal time windows and IgE levels in newborns. Pediatric Allergy and Immunology 2011;22(1 Pt 1):75-84. |
R833292 (2011) R833292 (2012) R833292 (Final) |
Exit |
|
Hertz-Picciotto I, Charles MJ, James RA, Keller JA, Willman E, Teplin S. In utero polychlorinated biphenyl exposures in relation to fetal and early childhood growth. Epidemiology 2005;16(5):648-656. |
R833292 (2007) R833292 (Final) R829388 (2006) R829388 (2007) R829388 (Final) |
Exit |
|
Hertz-Picciotto I, Croen LA, Hansen R, Jones CR, van de Water J, Pessah IN. The CHARGE Study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environmental Health Perspectives 2006;114(7):1119-1125. |
R833292 (2007) R833292 (Final) R829388 (2006) R829388 (Final) R829388C004 (2005) |
|
|
Hertz-Picciotto I, Baker RJ, Yap PS, Dostal M, Joad JP, Lipsett M, Greenfield T, Herr CE, Benes I, Shumway RH, Pinkerton KE, Sram R. Early childhood lower respiratory illness and air pollution. Environmental Health Perspectives 2007;115(10):1510-1518. |
R833292 (2007) R833292 (Final) R829388 (2007) R829388 (Final) R831540 (Final) |
|
|
Hertz-Picciotto I, Park HY, Dostal M, Kocan A, Trnovec T, Sram R. Prenatal exposures to persistent and non-persistent organic compounds and effects on immune system development. Basic and Clinical Pharmacology and Toxicology 2008;102(2):146-154. |
R833292 (2008) R833292 (2009) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Hertz-Picciotto I, Jusko TA, Willman EJ, Baker RJ, Keller JA, Teplin SW, Charles MJ. A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio. Environmental Health 2008;7:37. |
R833292 (2009) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Hertz-Picciotto I, Delwiche L. The rise in autism and the role of age at diagnosis. Epidemiology 2009;20(1):84-90. |
R833292 (2009) R833292 (Final) |
Exit Exit |
|
Hertz-Picciotto I, Cassady D, Lee K, Bennett DH, Ritz B, Vogt R. Study of Use of Products and Exposure-Related Behaviors (SUPERB):study design, methods, and demographic characteristics of cohorts. Environmental Health 2010;9:54 (14 pp.). |
R833292 (2010) R833292 (Final) R831540 (Final) |
Exit Exit Exit |
|
Hertz-Picciotto I, Green PG, Delwiche L, Hansen R, Walker C, Pessah IN. Blood mercury concentrations in CHARGE Study children with and without autism. Environmental Health Perspectives 2010;118(1):161-166. |
R833292 (2009) R833292 (Final) |
|
|
Hertz-Picciotto I, Bergman A, Fangstrom B, Rose M, Krakowiak P, Pessah I, Hansen R, Bennett DH. Polybrominated diphenyl ethers in relation to autism and developmental delay: a case-control study. Environmental Health 2011;10(1):1. |
R833292 (2011) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Heuer LS, Rose M, Ashwood P, Van de Water J. Decreased levels of total immunoglobulin in children with autism are not a result of B cell dysfunction. Journal of Neuroimmunology 2012;251(1-2):94-102. |
R833292 (2012) R833292 (Final) |
Exit |
|
Heuer L, Ashwood P, Schauer J, Goines P, Krakowiak P, Hertz-Picciotto I, Hansen R, Croen LA, Pessah IN, Van de Water J. Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms. Autism Research 2008;1(5):275-283. |
R833292 (2009) R833292 (Final) |
Exit |
|
Heuer L, Braunschweig D, Ashwood P, Van de Water J, Campbell DB. Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression. Translational Psychiatry 2011;1:e48. |
R833292 (2011) R833292 (Final) |
Exit Exit Exit |
|
Hillyard SL, German JB. Non-essential dietary factors: from test tube to lifespan. Journal of the Science of Food and Agriculture 2007;87(10):1802-1805. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Hillyard SL, German JB. Quantitative lipid analysis and life span of the fat-3 mutant of Caenorhabditis elegans. Journal of Agricultural and Food Chemistry 2009;57(8):3389-3396. |
R833292 (Final) |
Exit |
|
Hinde K, German JB. Food in an evolutionary context: insights from mother's milk. Journal of the Science of Food and Agriculture 2012;92(11):2219-2223. |
R833292 (2012) |
Exit |
|
Horvathova M, Jahnova E, Palkovicova L, Trnovec T, Hertz-Picciotto I. Dynamics of lymphocyte subsets in children living in an area polluted by polychlorinated biphenyls. Journal of Immunotoxicology 2011;8(4):333-345. |
R833292 (2012) |
Exit |
|
Horvathova M, Jahnova E, Palkovicova L, Trnovec T, Hertz-Picciotto I. The kinetics of cell surface receptor expression in children perinatally exposed to polychlorinated biphenyls. Journal of Immunotoxicology 2011;8(4):367-380. |
R833292 (2012) |
Exit |
|
Howards PP, Hertz-Picciotto I. Invited commentary: disinfection by-products and pregnancy loss—lessons. American Journal of Epidemiology 2006;164(11):1052-1055. |
R833292 (2007) R833292 (Final) R829388 (2007) R829388 (Final) R831540 (Final) |
Exit Exit Exit |
|
Hua S, Nwosu CC, Strum JS, Seipert RR, An HJ, Zivkovic AM, German JB, Lebrilla CB. Site-specific protein glycosylation analysis with glycan isomer differentiation. Analytical and Bioanalytical Chemistry 2012;403(5):1291-1302. |
R833292 (2012) R833292 (Final) |
Exit Exit |
|
Huang H, Nishi K, Gee SJ, Hammock BD. Evaluation of chiral α-cyanoesters as general fluorescent substrates for screening enantioselective esterases. Journal of Agricultural and Food Chemistry 2006;54(3):694-699. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit |
|
Hwang H-M, Park E-K, Young TM, Hammock BD. Occurrence of endocrine-disrupting chemicals in indoor dust. Science of the Total Environment 2008;404(1):26-35. |
R833292 (Final) |
Exit Exit Exit |
|
Inceoglu B, Schmelzer KR, Morisseau C, Jinks SL, Hammock BD. Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs). Prostaglandins & Other Lipid Mediators 2007;82(1-4):42-49. |
R833292 (Final) R829388 (Final) |
Exit |
|
Jaubert PJ, Golub MS, Lo YY, Germann SL, Dehoff MH, Worley PF, Kang SH, Schwarz MK, Seeburg PH, Berman RF. Complex, multimodal behavioral profile of the Homer1 knockout mouse. Genes, Brain and Behavior 2007;6(2):141-154. |
R833292 (2007) R833292 (Final) R829388 (2006) R829388 (Final) R829388C005 (2005) |
Exit Exit Exit |
|
Jusko TA, Koepsell TD, Baker RJ, Greenfield TA, Willman EJ, Charles MJ, Teplin SW, Checkoway H, Hertz-Picciotto I. Maternal DDT exposures in relation to fetal and 5-year growth. Epidemiology 2006;17(6):692-700. |
R833292 (2007) R833292 (Final) R829388 (2007) R829388 (Final) |
Exit |
|
Jusko TA, De Roos AJ, Schwartz SM, Lawrence BP, Palkovicova L, Nemessanyi T, Drobna B, Fabisikova A, Kocan A, Sonneborn D, Jahnova E, Kavanagh TJ, Trnovec T, Hertz-Picciotto I. A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age. Environmental Research 2010;110(4):388-395. |
R833292 (2010) R833292 (Final) |
Exit Exit |
|
Kania-Korwel I, Barnhart CD, Stamou M, Truong KM, El-Komy MHME, Lein PJ, Veng-Pedersen P, Lehmler H-J. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) and its hydroxylated metabolites are enantiomerically enriched in female mice. Environmental Science & Technology 2012;46(20):11393-11401. |
R833292 (2012) |
Exit |
|
Kenet T, Froemke RC, Schreiner CE, Pessah IN, Merzenich MM. Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex. Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7646-7651. |
R833292 (2007) R833292 (2008) R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Kim H-J, Ahn KC, Ma SJ, Gee SJ, Hammock BD. Development of sensitive immunoassays for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroid exposure. Journal of Agricultural and Food Chemistry 2007;55(10):3750-3757. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Kim H-J, McCoy M, Gee SJ, Gonzalez-Sapienza GG, Hammock BD. Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules. Analytical Chemistry 2011;83(1):246-253. |
R833292 (2012) R833292 (Final) |
Exit |
|
Kim H-J, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Analytical Chemistry 2012;84(2):1165-1171. |
R833292 (2012) R833292 (Final) |
Exit |
|
Kim H-J, Rossotti MA, Ahn KC, Gonzalez-Sapienza GG, Gee SJ, Musker R, Hammock BD. Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47. Analytical Biochemistry 2010;401(1):38-46. |
R833292 (Final) |
Exit Exit Exit |
|
Kim KH, Inan SY, Berman RF, Pessah IN. Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substituted polychlorinated biphenyls in the hippocampal slice preparation. Toxicology and Applied Pharmacology 2009;237(2):168-177. |
R833292 (Final) R829388 (Final) R829388C006 (2005) |
Exit Exit Exit |
|
Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN. Para-and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity. Environmental Health Perspectives 2011;119(4):519-526. |
R833292 (2012) R833292 (Final) R829388 (2006) R829388 (Final) |
|
|
Kim KH, Pessah IN. Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxicity ex vivo. NeuroToxicology 2011;32(6):981-985. |
R833292 (2011) R833292 (Final) |
Exit Exit Exit |
|
Koenig CM, Walker CK, Qi L, Pessah IN, Berman RF. Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice. PLoS ONE 2012;7(6):e38911 (7 pp.). |
R833292 (2012) R833292 (Final) |
Exit Exit |
|
Koenig CM, Lango J, Pessah IN, Berman RF. Maternal transfer of BDE-47 to offspring and neurobehavioral development in C57BL/6J mice. Neurotoxicology and Teratology 2012;34(6):571-580. |
R833292 (2012) R835432 (2013) |
Exit Exit Exit |
|
Krakowiak P, Goodlin-Jones B, Hertz-Picciotto I, Croen LA, Hansen RL. Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based study. Journal of Sleep Research 2008;17(2):197-206. |
R833292 (2007) R833292 (2008) R833292 (2009) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Krakowiak P, Walker CK, Bremer AA, Baker AS, Ozonoff S, Hansen RL, Hertz-Picciotto I. Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics 2012;129(5):e1121-e1128. |
R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Lange MC, Lemay DG, German JB. A multi-ontology framework to guide agriculture and food towards diet and health. Journal of the Science of Food and Agriculture 2007;87(8):1427-1434. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Lee H, Lerno Jr. LA, Choe Y, Chu CS, Gillies LA, Grimm R, Lebrilla CB, German JB. Multiple precursor ion scanning of gangliosides and sulfatides with a reversed-phase microfluidic chip and quadrupole time-of-flight mass spectrometry. Analytical Chemistry 2012;84(14):5905-5912. |
R833292 (2012) |
Exit |
|
Lein PJ, Barnhart CD, Pessah IN. Acute hippocampal slice preparation and hippocampal slice cultures. Methods in Molecular Biology 2011;758:115-134. |
R833292 (Final) |
Exit |
|
Lemay DG, Neville MC, Rudolph MC, Pollard KS, German JB. Gene regulatory networks in lactation: identification of global principles using bioinformatics. BMC Systems Biology 2007;1:56 (24 pp.). |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Lemay DG, Zivkovic AM, German JB. Building the bridges to bioinformatics in nutrition research. American Journal of Clinical Nutrition 2007;86(5):1261-1269. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Lemay DG, Lynn DJ, Martin WF, Neville MC, Casey TM, Rincon G, Kriventseva EV, Barris WC, Hinrichs AS, Molenaar AJ, Pollard KS, Maqbool NJ, Singh K, Murney R, Zdobnov EM, Tellam RL, Medrano JF, German JB, Rijnkels M. The bovine lactation genome: insights into the evolution of mammalian milk. Genome Biology 2009;10(4):R43 (18 pp.). |
R833292 (Final) |
Exit Exit Exit |
|
Li L. Survival prediction of diffuse large-B-cell lymphoma based on both clinical and gene expression information. Bioinformatics 2006;22(4):466-471. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Li N, Liu J-Y, Timofeyev V, Qiu H, Hwang SH, Tuteja D, Lu L, Yang J, Mochida H, Low R, Hammock BD, Chiamvimonvat N. Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: insight gained using metabolomic approaches. Journal of Molecular and Cellular Cardiology 2009;47(6):835-845. |
R833292 (Final) |
Exit |
|
Li N, Liu J-Y, Qiu H, Harris TR, Sirish P, Hammock BD, Chiamvimonvat N. Use of metabolomic profiling in the study of arachidonic acid metabolism in cardiovascular disease. Congestive Heart Failure 2011;17(1):42-46. |
R833292 (Final) |
Exit Exit Exit |
|
Liu J, Koscielska KA, Cao Z, Hulsizer S, Grace N, Mitchell G, Nacey C, Githinji J, McGee J, Garcia-Arocena D, Hagerman RJ, Nolta J, Pessah IN, Hagerman PJ. Signaling defects in iPSC-derived fragile X premutation neurons. Human Molecular Genetics 2012;21(17):3795-3805. |
R833292 (2012) R835432 (2013) |
Exit Exit Exit |
|
Lyall K, Song L, Botteron K, Croen L, Dager S, Fallin M, Hazlett H, Kauffman E, Landar R, Ladd-Acosta C. The Association Between Parental Age and Autism-Related Outcomes in Children at High Familial Risk for Autism. AUTISM RESEARCH 2020;. |
R833292 (Final) |
Exit |
|
Magby JP, Neal AP, Atchison WD, Pessah IP, Shafer TJ. Channelopathies: summary of the hot topic keynotes session. NeuroToxicology 2011;32(5):661-665. |
R833292 (2011) R833292 (Final) |
Exit Exit Exit |
|
Martin LA, Ashwood P, Braunschweig D, Cabanlit M, Van de Water J, Amaral DG. Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism. Brain, Behavior, and Immunity 2008;22(6):806-816. |
R833292 (2008) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Masuno MN, Pessah IN, Olmstead MM, Molinski TF. Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex. Journal of Medicinal Chemistry 2006;49(15):4497-4511. |
R833292 (2007) R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
McCanlies EC, Fekedulegn D, Mnatsakanova A, Burchfiel CM, Sanderson WT, Charles LE, Hertz-Picciotto I. Parental occupational exposures and autism spectrum disorder. Journal of Autism and Developmental Disorders 2012;42(11):2323-2334. |
R833292 (2012) R833292 (Final) R836159 (2019) |
Exit |
|
Merin N, Young GS, Ozonoff S, Rogers SJ. Visual fixation patterns during reciprocal social interaction distinguish a subgroup of 6-month-old infants at-risk for autism from comparison infants. Journal of Autism and Developmental Disorders 2007;37(1):108-121. |
R833292 (2007) R833292 (Final) R829388 (2007) R829388 (Final) |
Exit |
|
Mitchell MM, Woods R, Chi L-H, Schmidt RJ, Pessah IN, Kostyniak PJ, LaSalle JM. Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder. Environmental and Molecular Mutagenesis 2012;53(8):589-598. |
R833292 (2012) R833292 (Final) R835432 (2013) |
Exit Exit Exit |
|
Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environmental Health Perspectives 2009;117(12):1867-1872. |
R833292 (2009) R833292 (Final) |
|
|
Nadig AS, Ozonoff S, Young GS, Rozga A, Sigman M, Rogers SJ. A prospective study of response to name in infants at risk for autism. Archives of Pediatrics & Adolescent Medicine 2007;161(4):378-383. |
R833292 (2007) R833292 (Final) R829388 (2007) R829388 (Final) |
Exit Exit |
|
Nagarajan RP, Patzel KA, Martin M, Yasui DH, Swanberg SE, Hertz-Picciotto I, Hansen RL, Van de Water J, Pessah IN, Jiang R, Robinson WP, LaSalle JM. MECP2 promoter methylation and X chromosome inactivation in autism. Autism Research 2008;1(3):169-178. |
R833292 (2008) R833292 (2009) R833292 (Final) |
Exit |
|
Newman JW, Kaysen GA, Hammock BD, Shearer GC. Proteinuria increases oxylipid concentrations in VLDL and HDL, but not LDL particles in the rat. Journal of Lipid Research 2007;48(8):1792-1800. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Newschaffer CJ, Croen LA, Fallin MD, Hertz-Picciotto I, Nguyen DV, Lee NL, Berry CA, Farzadegan H, Hess HN, Landa RJ, Levy SE, Massolo ML, Meyerer SC, Mohammed SM, Oliver MC, Ozonoff S, Pandey J, Schroeder A, Shedd-Wise KM. Infant siblings and the investigation of autism risk factors. Journal of Neurodevelopmental Disorders 2012;4(1):7 (16 pp.). |
R833292 (2012) |
Full Text PDF Exit Abstract & Full Text HTML Exit |
|
Nguyen DV, Senturk D. Distortion diagnostics for covariate-adjusted regression: graphical techniques based on local linear modeling. Journal of Data Science 2007;5(4):471-490. |
R833292 (Final) R829388 (Final) |
Exit Exit |
|
Nguyen DV, Senturk D, Carroll RJ. Covariate-adjusted linear mixed effects model with an application to longitudinal data. Journal of Nonparametric Statistics 20(6):459-481. |
R833292 (Final) |
Exit |
|
Ninonuevo MR, Park Y, Yin H, Zhang J, Ward RE, Clowers BH, German JB, Freeman SL, Killeen K, Grimm R, Lebrilla CB. A strategy for annotating the human milk glycome. Journal of Agricultural and Food Chemistry 2006;54(20):7471-7480. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Ninonuevo MR, Ward RE, LoCascio RG, German JB, Freeman SL, Barboza M, Mills DA, Lebrilla CB. Methods for the quantitation of human milk oligosaccharides in bacterial fermentation by mass spectometry. Analytical Biochemistry 2007;361(1):15-23. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Oberbauer AM, German JB, Murray JD. Growth hormone enhances arachidonic acid metabolites in a growth hormone transgenic mouse. Lipids 2011;46(6):495-504. |
R833292 (2012) R833292 (Final) |
Exit |
|
Oh J, Bennett D, Calafat A, Tancredi D, Roa D, Schmidt R, Hertz-Picciotto I, Shin H. Prenatal exposure to per-and polyfluoroalkyl substances in association with autism spectrum disorder in the MARBLES study. Enviornmenal International 2020;(106328). |
R833292 (Final) R829388 (Final) R829389 (Final) R835432 (Final) |
Exit Exit |
|
Oh J, Bennett D, Tancredi D, Calafat A, Schmidt R, Hertz-Picciotto I, Shin H. Longitudinal Changes in Maternal Serum Concentrations of Per-and Polyfluoroalkyl Substances from Pregnancy to Two Years Postpartum. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2022;56(16):11449-11459. |
R833292 (Final) |
Exit Exit |
|
Onore CE, Nordahl CW, Young GS, Van de Water JA, Rogers SJ, P Ashwood P. Levels of soluble adhesion molecules PECAM-1 and P-selectin are decreased in children with autism spectrum disorder. Biological Psychiatry 2012;72(12):1020-1025. |
R833292 (2012) |
Exit |
|
Onore C, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen R, Van de Water J, Ashwood P. Decreased cellular IL-23 but not IL-17 production in children with autism spectrum disorders. Journal of Neuroimmunology 2009;216(1-2):126-129. |
R833292 (2009) R833292 (2010) R833292 (Final) |
Exit |
|
Onore C, Careaga M, Ashwood P. The role of immune dysfunction in the pathophysiology of autism. Brain, Behavior, and Immunity 2012;26(3):383-392. |
R833292 (2011) R833292 (Final) |
Exit Exit |
|
Ostrovskaya O, Goyal R, Osman N, McAllister CE, Pessah IN, Hume JR, Wilson SM. Inhibition of ryanodine receptors by 4-(2-aminopropyl)-3,5-dichloro-N,N-dimethylaniline (FLA 365) in canine pulmonary arterial smooth muscle cells. Journal of Pharmacology and Experimental Therapeutics 2007;323(1):381-390. |
R833292 (2007) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Ozonoff S, Young GS, Goldring S, Greiss-Hess L, Herrera AM, Steele J, Macari S, Hepburn S, Rogers SJ. Gross motor development, movement abnormalities, and early identification of autism. Journal of Autism and Developmental Disorders 2008;38(4):644-656. |
R833292 (2007) R833292 (Final) R829388 (2007) R829388 (Final) |
Exit |
|
Ozonoff S, Heung K, Byrd R, Hansen R, Hertz-Picciotto I. The onset of autism: patterns of symptom emergence in the first years of life. Autism Research 2008;1(6):320-328. |
R833292 (2009) R833292 (Final) |
Exit |
|
Ozonoff S, Iosif A-M, Young GS, Hepburn S, Thompson M, Colombi C, Cook IC, Werner E, Goldring S, Baguio F, Rogers SJ. Onset patterns in autism: correspondence between home video and parent report. Journal of the American Academy of Child & Adolescent Psychiatry 2011;50(8):796-806.e1. |
R833292 (2012) |
Exit |
|
Ozonoff S. The first cut is the deepest: why do the reported effects of treatments decline over trials? Journal of Child Psychology and Psychiatry 2011;52(7):729-730 (editorial). |
R833292 (2012) |
Exit Exit Exit |
|
Palkovicova L, Ursinyova M, Masanova V, Yu Z, Hertz-Picciotto I. Maternal amalgam dental fillings as the source of mercury exposure in developing fetus and newborn. Journal of Exposure Science & Environmental Epidemiology 2008;18(3):326-331. |
R833292 (2007) R833292 (2008) R833292 (2009) R833292 (Final) R829388 (2007) R829388 (Final) |
Exit Exit |
|
Parenti M, Schmidt R, Ozonoff S, Shin H, Tancredi D, Daniel J, Krakowiak P, Hertz-Picciotto I, Walker C, SLupsky C. Maternal Serum and Placental Metabolomes in Association with Prenatal Phthalate Exposure and Neurodevelopmental Outcomes in the MARBLES Cohort. METABOLITES 2022;12(9):829. |
R833292 (Final) R829388 (Final) |
Exit Exit |
|
Park HY, Hertz-Picciotto I, Sovcikova E, Kocan A, Drobna B, Trnovec T. Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study. Environmental Health 2010;9:51. |
R833292 (2010) R833292 (Final) |
Exit Exit Exit |
|
Park H-Y, Hertz-Picciotto I, Petrik J, Palkovicova L, Kocan A, Trnovec T. Prenatal PCB exposure and thymus size at birth in neonates in Eastern Slovakia. Environmental Health Perspectives 2008;116(1):104-109. |
R833292 (Final) R829388 (Final) |
|
|
Park H-Y, Park J-S, Sovcikova E, Kocan A, Linderholm L, Bergman A, Trnovec T, Hertz-Picciotto I. Exposure to hydroxylated polychlorinated biphenyls (OH-PCBs) in the prenatal period and subsequent neurodevelopment in Eastern Slovakia. Environmental Health Perspectives 2009;117(10):1600-1606. |
R833292 (Final) |
|
|
Park J-S, Bergman A, Linderholm L, Athanasiadou M, Kocan A, Petrik J, Drobna B, Trnovec T, Charles MJ, Hertz-Picciotto I. Placental transfer of polychlorinated biphenyls, their hydroxylated metabolites and pentachlorophenol in pregnant women from eastern Slovakia. Chemosphere 2008;70(9):1676-1684. |
R833292 (Final) |
Exit Exit Exit |
|
Paul R, Pessah IN, Gane L, Ono M, Hagerman PJ, Brunberg JA, Tassone F, Bourgeois JA, Adams PE, Nguyen DV, Hagerman R. Early onset of neurological symptoms in fragile X premutation carriers exposed to neurotoxins. Neurotoxicology 2010;31(4):399-402. |
R833292 (2009) R833292 (Final) |
Exit Exit Exit |
|
Pessah IN, Hansen LG, Albertson TE, Garner CE, Ta TA, Do Z, Kim KH, Wong PW. Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). Chemical Research in Toxicology 2006;19(1):92-101. |
R833292 (2007) R833292 (2009) R833292 (Final) R829388 (2006) R829388 (Final) R829388C006 (2005) |
Exit Exit Exit |
|
Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van de Water J, Berman RF. Immunologic and neurodevelopmental susceptibilities of autism. NeuroToxicology 2008;29(3):532-545. |
R833292 (2008) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W. Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chemical Research in Toxicology 2009;22(1):201-207. |
R833292 (Final) |
Exit |
|
Pessah IN, Cherednichenko G, Lein PJ. Minding the calcium store: ryanodine receptor activation as a convergent mechanism of PCB toxicity. Pharmacology & Therapeutics 2010;125(2):260-285. |
R833292 (2009) R833292 (Final) R829388 (Final) |
Exit Exit |
|
Pessah IN, Truong K. Additional Safety Assessments Needed for Diamide Insecticides.STOXICOLOGICAL SCIENCES 2019:170(2):509-524 |
R833292 (Final) |
Exit Exit |
|
Philippat C, Bennett DH, Krakowiak P, Rose M, Hwang HM, Hertz-Picciotto I. Phthalate concentrations in house dust in relation to autism spectrum disorder and developmental delay in the CHildhood Autism Risks from Genetics and the Environment (CHARGE) study. Environmental Health 2015;14:56 (10 pp.). |
R833292 (Final) R829388 (Final) R835432 (2014) |
Exit Exit Exit |
|
Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD, Pessah IN. Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. Journal of Biological Chemistry 2007;282(12):8667-8677. |
R833292 (2007) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Qi L, Wang Y-F, He Y. A comparison of multiple imputation and fully augmented weighted estimators for Cox regression with missing covariates. Statistics in Medicine 2010;29(25):2592-2604. |
R833292 (Final) |
Exit |
|
Qiu H, Li N, Liu J-Y, Harris TR, Hammock BD, Chiamvimonvat N. Soluble epoxide hydrolase inhibitors and heart failure. Cardiovascular Therapeutics 2011;29(2):99-111. |
R833292 (Final) |
Exit Exit Exit |
|
Rose D, Ashwood P. Rapid Communication:Plasma Interleukin-35 in Children with Autism . Brain Sciences2019;9(7):152;. |
R833292 (Final) |
Exit Exit |
|
Rose M, Bennett DH, Bergman A, Fangstrom B, Pessah IN, Hertz-Picciotto I. PBDEs in 2-5 year-old children from California and associations with diet and indoor environment. Environmental Science & Technology 2010;44(7):2648-2653. |
R833292 (2009) R833292 (2010) R833292 (Final) |
Exit |
|
Rossi CC, Van de Water J, Rogers SJ, Amaral DG. Detection of plasma autoantibodies to brain tissue in young children with and without autism spectrum disorders. Brain, Behavior, and Immunity 2011;25(6):1123-1135. |
R833292 (2011) R833292 (2012) R833292 (Final) |
Exit Exit |
|
Samso M, Feng W, Pessah IN, Allen PD. Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. PLoS Biology 2009;7(4):e85 (16 pp.). |
R833292 (2009) R833292 (Final) |
Exit Exit |
|
Schmelzer KR, Inceoglu B, Kubala L, Kim IH, Jinks SL, Eiserich JP, Hammock BD. Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors. Proceedings of the National Academy of Sciences of the United States of America 2006;103(37):13646-13651. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Schmelzer KR, Wheelock AM, Dettmer K, Morin D, Hammock BD. The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways. Environmental Health Perspectives 2006;114(9):1354-1360. |
R833292 (Final) R829388 (Final) |
|
|
Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tancredi DJ, Tassone F, Hertz-Picciotto I. Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism. Epidemiology 2011;22(4):476-485. |
R833292 (2011) R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Schmidt RJ, Tancredi DJ, Ozonoff S, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tassone F, Hertz-Picciotto I. Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. American Journal of Clinical Nutrition 2012;96(1):80-89. |
R833292 (2009) R833292 (2012) R833292 (Final) R829388 (Final) |
Exit Exit |
|
Schmidt RJ, Tancredi DJ, Krakowiak P, Hansen RL, Ozonoff S. Maternal intake of supplemental iron and risk of autism spectrum disorder. American Journal of Epidemiology 2014;180(9):890-900. |
R833292 (Final) R829388 (Final) R835432 (2014) |
Exit Exit Exit |
|
Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Sconberg JL, Schmidt LC, Volk HE, Tassone F. Selected vitamin D metabolic gene variants and risk for autism spectrum disorder in the CHARGE Study. Early Human Development 2015;91(8):483-489. |
R833292 (Final) R829388 (Final) R835432 (2014) |
Exit Exit Exit |
|
Schmidt RJ, Kogan V, Shelton JF, Delwiche L, Hansen RL, Ozonoff S, Ma CC, McCanlies EC, Bennett DH, Hertz-Picciotto I, Tancredi DJ, Volk HE. Combined prenatal pesticide exposure and folic acid intake in relation to autism spectrum disorder. Environmental Health Perspectives 2017;125(9):097007 (12 pp.). |
R833292 (Final) R829388 (Final) R835432 (2017) |
|
|
Schmidt RJ, Niu Q, Eyles DW, Hansen RL, Iosif, A. Neonatal vitamin D status in relation to autism spectrum disorder and developmental delay in the CHARGE case–control study. Autism Research 2019;12(6):976-988. |
R833292 (Final) |
Exit |
|
Senturk D, Nguyen DV. Partial covariate adjusted regression. Journal of Statistical Planning and Inference 2009;139(2):454-468. |
R833292 (Final) |
Exit Exit Exit |
|
Shearer GC, Newman JW, Hammock BD, Kaysen GA. Graded effects of proteinuria on HDL structure in nephrotic rats. Journal of the American Society of Nephrology 2005;16(5):1309-1319. |
R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Shelton JF, Tancredi DJ, Hertz-Picciotto I. Independent and dependent contributions of advanced maternal and paternal ages to autism risk. Autism Research 2010;3(1):30-39. |
R833292 (2009) R833292 (Final) |
Exit Exit Exit |
|
Shelton JF, Hertz-Picciotto I, Pessah IN. Tipping the balance of autism risk: potential mechanisms linking pesticides and autism. Environmental Health Perspectives 2012;120(7):944-951. |
R833292 (2012) R833292 (Final) R835432 (2013) |
|
|
Smilowitz JT, Dillard CJ, German JB. Milk beyond essential nutrients: the metabolic food. Australian Journal of Dairy Technology 2005;60(2):77-83. |
R833292 (Final) R829388 (Final) |
Exit Exit |
|
Sonneborn D, Park HY, Petrik J, Kocan A, Palkovicova L, Trnovec T, Nguyen D, Hertz-Picciotto I. Prenatal polychlorinated biphenyl exposures in eastern Slovakia modify effects of social factors on birthweight. Paediatric and Perinatal Epidemiology 2008;22(3):202-213. |
R833292 (Final) R829388 (Final) R831540 (Final) |
Exit Exit |
|
Sonneborn D, Park HY, Babinska K, Palkovicova L, Trnovec T, Kocan A, Nguyen DV, Hertz-Picciotto I. Serum PCB concentrations in relation to locally produced food items in eastern Slovakia. Journal of Exposure Science & Environmental Epidemiology 2008;18(6):581-587. |
R833292 (2009) R833292 (Final) R829388 (Final) R831540 (Final) |
Exit Exit |
|
Sotelo-Orizco J, Schmidt J, Slupsky C, Hertz-Picciotto I. Investigating the Urinary Metabolome in the First Year of Life and Its Association with Later Diagnosis of Autism Spectrum Disorder or Non-Typical Neurodevelopment in the MARBLES Study. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCE 2023;24(11):9454. |
R833292 (Final) |
Exit |
|
Stamova BS, Apperson M, Walker WL, Tian Y, Xu H, Adamczy P, Zhan X, Liu D-Z, Ander BP, Liao IH, Gregg JP, Turner RJ, Jickling GC, Lit L, Sharp FR. Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood. BMC Medical Genomics 2009;2:49. |
R833292 (Final) |
Exit Exit Exit |
|
Stamova BS, Tian Y, Nordahl CW, Shen MD, Rogers S, Amaral DG, Sharp FR. Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders. Molecular Autism 2013;4:30 (16 pp.). |
R833292 (2012) |
Exit Exit |
|
Stamova B, Green PG, Tian Y, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Teng J, Gregg JP, Ashwood P, Van de Water J, Sharp FR. Correlations between gene expression and mercury levels in blood of boys with and without autism. Neurotoxicity Research 2011;19(1):31-48. |
R833292 (2009) R833292 (2010) R833292 (Final) |
Exit Exit Exit |
|
Sundekilde UK, Barile D, Meyrand M, Poulsen NA, Larsen LB, Lebrilla CB, German JB, Bertram HC. Natural variability in bovine milk oligosaccharides from Danish Jersey and Holstein-Friesian breeds. Journal of Agricultural and Food Chemistry 2012;60(24):6188-6196. |
R833292 (2012) |
Exit |
|
Ta TA, Feng W, Molinski TF, Pessah IN. Hydroxylated xestospongins block inositol-1,4,5-trisphosphate-induced Ca2+ release and sensitive Ca2+-induced Ca2+ release mediated by ryanodine receptors. Molecular Pharmacology 2006;69(2):532-538. |
R833292 (Final) R829388 (2006) R829388 (Final) R829388C006 (2005) |
Exit Exit Exit |
|
Ta TA, Pessah IN. Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95). NeuroToxicology 2007;28(4):770-779. |
R833292 (2007) R833292 (2008) R833292 (2009) R833292 (Final) R829388 (2006) R829388 (Final) |
Exit Exit Exit |
|
Ta TA, Koenig CM, Golub MS, Pessah IN, Qi L, Aronov PA, Berman RF. Bioaccumulation and behavioral effects of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) in perinatally exposed mice. Neurotoxicology and Teratology 2011;33(3):393-404. |
R833292 (2011) R833292 (Final) |
Exit Exit Exit |
|
Tabares-da Rosa S, Rossotti M, Carleiza C, Carrion F, Pritsch O, Ahn KC, Last JA, Hammock BD, Gonzalez-Sapienza G. Competitive selection from single domain antibody libraries allows isolation of high-affinity antihapten antibodies that are not favored in the llama immune response. Analytical Chemistry 2011;83(18):7213-7220. |
R833292 (2012) |
Exit |
|
Tassone F, Qi L, Zhang W, Hansen RL, Pessah IN, Hertz-Picciotto I. MAOA, DΒH and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders. Autism Research 2011;4(4):250-261. |
R833292 (2011) R833292 (Final) |
Exit |
|
Tian Y, Green PG, Stamova B, Hertz-Picciotto I, Pessah IN, Hansen R, Yang X, Gregg JP, Ashwood P, Jickling G, Van de Water J, Sharp FR. Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls. Neurotoxicity Research 2011;19(1):1-13. |
R833292 (2009) R833292 (Final) |
Exit Exit Exit |
|
Trnovec T, Dedík L, Jusko TA, Lancz K, Palkovicova L, Kocan A, Sovcikova E, Wimmerova S, Tihanyi J, Patayova H, Hertz-Picciotto I. Assessment of exposure to PCB 153 from breast feeding and normal food intake in individual children using a system approach model. Chemosphere 2011;85(11):1687-1693. |
R833292 (2012) |
Exit Exit Exit |
|
Ulu A, Davis BB, Tsai H-J, Kim I-H, Morisseau C, Inceoglu B, Fiehn O, Hammock BD, Weiss RH. Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein E-knockout mouse model. Journal of Cardiovascular Pharmacology 2008;52(4):314-323. |
R833292 (Final) |
Exit Exit Exit |
|
Van Meter KC, Christiansen LE, Hertz-Picciotto I, Azari R, Carpenter TE. A procedure to characterize geographic distributions of rare disorders in cohorts. International Journal of Health Geographics 2008;7:26. |
R833292 (Final) |
Exit Exit Exit |
|
Van Meter KC, Christiansen LE, Delwiche, LD, Azari R, Carpenter TE, Hertz-Picciotto I. Geographic distribution of autism in California: a retrospective birth cohort analysis. Autism Research 2010;3(1):19-29. |
R833292 (2009) R833292 (Final) |
Exit |
|
Verner MA, Sonneborn D, Lancz K, Muckle G, Ayotte P, Dewailly E, Kocan A, Palkovicova L, Trnovec T, Haddad S, Hertz-Picciotto I, Eggesbo M. Toxicokinetic modeling of persistent organic pollutant levels in blood from birth to 45 months of age in longitudinal birth cohort studies. Environmental Health Perspectives 2013;121(1):131-137. |
R833292 (2012) |
|
|
Vogel CFA, Goth SR, Dong B, Pessah IN, Matsumura F. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochemical and Biophysical Research Communications 2008;375(3):331-335. |
R833292 (Final) |
Exit Exit Exit |
|
Volk HE, Hertz-Picciotto I, Delwiche L, Lurmann F, McConnell R. Residential proximity to freeways and autism in the CHARGE Study. Environmental Health Perspectives 2011;119(6):873-877. |
R833292 (2011) R833292 (Final) |
|
|
Ward RE, Ninonuevo M, Mills DA, Lebrilla CB, German JB. In vitro fermentation of breast milk oligosaccharides by Bifidobacterium infantis and Lactobacillus gasseri. Applied and Environmental Microbiology 2006;72(6):4497-4499. |
R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Ward RE, Ninonuevo M, Mills DA, Lebrilla CB, German JB. In vitro fermentability of human milk oligosaccharides by several strains of bifidobacteria. Molecular Nutrition & Food Research 2007;51(11):1398-1405. |
R833292 (Final) R829388 (Final) |
Exit |
|
Wayman GA, Bose DD, Yang D, Lesiak A, Bruun D, Impey S, Ledoux V, Pessah IN, Lein PJ. PCB 95 modulates calcium-dependent signaling pathway responsible for activity-dependent dendritic growth. Environmental Health Perspectives 2012;120(7):1003-1009. |
R833292 (2012) R833292 (Final) |
|
|
Wayman GA, Yang D, Bose DD, Lesiak A, Ledoux V, Bruun D, Pessah IN, Lein PJ. PCB-95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. Environmental Health Perspectives 2012;120(7):997-1002. |
R833292 (2012) R833292 (Final) R835432 (2013) |
|
|
Wiest MM, German JB, Harvey DJ, Watkins SM, Hertz-Picciotto I. Plasma fatty acid profiles in autism: a case-control study. Prostaglandins, Leukotrienes, and Essential Fatty Acids 2009;80(4):221-227. |
R833292 (2009) R833292 (Final) |
Exit Exit |
|
Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral D, Van de Water J. Autoantibodies in autism spectrum disorders (ASD). Annals of the New York Academy of Sciences 2007;1107:79-91. |
R833292 (2007) R833292 (Final) R829388 (Final) |
Exit Exit |
|
Wills S, Cabanlit M, Bennett J, Ashwood P, Amaral DG, Van de Water J. Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders. Brain, Behavior, and Immunity 2009;23(1):64-74. |
R833292 (2008) R833292 (Final) |
Exit Exit Exit |
|
Wills S, Rossi CC, Bennett J, Martinez-Cerdeno V, Ashwood P, Amaral DG, Van de Water J. Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism. Molecular Autism 2011;2:5. |
R833292 (2011) R833292 (Final) |
Exit Exit Exit |
|
Woods R, Vallero RO, Golub MS, Suarez JK, Ta TA, Yasui DH, Chi LH, Kostyniak PJ, Pessah IN, Berman RF, LaSalle JM. Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation. Human Molecular Genetics 2012;21(11):2399-2411. |
R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Wu XM, Bennett DH, Ritz B, Frost J, Cassady D, Lee K, Hertz-Picciotto I. Residential insecticide usage in northern California homes with young children. Journal of Exposure Science & Environmental Epidemiology 2011;21(4):427-436. |
R833292 (2012) R831540 (Final) |
Exit Exit |
|
Wu XM, Bennett DH, Lee K, Cassady DL, Ritz B, Hertz-Picciotto I. Feasibility of using web surveys to collect time-activity data. Journal of Exposure Science & Environmental Epidemiology 2012;22(2):116-125. |
R833292 (2012) R831540 (Final) |
Exit Exit |
|
Wu X, Apte MG, Maddalena R, Bennett DH. Volatile organic compounds in small- and medium-sized commercial buildings in California. Environmental Science & Technology 2011;45(20):9075-9083. |
R833292 (2012) |
Exit |
|
Wu X, Bennett DH, Lee K, Cassady DL, Ritz B, Hertz-Picciotto I. Longitudinal variability of time-location/activity patterns of population at different ages:a longitudinal study in California. Environmental Health 2011;10:80 (15 pp.). |
R833292 (2012) R831540 (Final) |
Exit Exit Exit |
|
Yakes EA, Arsenault JE, Islam MM, Hossain MB, Ahmed T, German JB, Gillies LA, Rahman AS, Drake C, Jamil KM, Lewis BL, Brown KH. Intakes and breast-milk concentrations of essential fatty acids are low among Bangladeshi women with 24-48-month-old children. British Journal of Nutrition 2011;105(11):1660-1670. |
R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Yakes EA, Arsenault JE, Islam MM, Ahmed T, German JB, Drake C, Hossain MB, Lewis BL, Rahman AS, Jamil KM, Brown KH. Dietary intake of polyunsaturated fatty acids among breast-feeding and non-breast-feeding 24- to 48-month-old children in Bangladesh. Journal of Pediatric Gastroenterology and Nutrition 2011;52(3):351-359. |
R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Yang D, Kim KH, Phimister AV, Bachstetter AD, Ward TR, Stackman RW, Mervis RF, Wisniewski AB, Klein SL, Kodavanti PRS, Anderson KA, Wayman G, Pessah IN, Lein PJ. Developmental exposure to polychlorinated biphenyls interferes with experience-dependent dendritic plasticity and ryanodine receptor expression in weanling rats. Environmental Health Perspectives 2009;117(3):426-435. |
R833292 (Final) |
|
|
Yang J, Dong H, Hammock BD. Profiling the regulatory lipids: another systemic way to unveil the biological mystery. Current Opinion in Lipidology 2011;22(3):197-203. |
R833292 (2012) |
Exit |
|
Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR. Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology 2006;105(6):1164-1175. |
R833292 (2007) R833292 (Final) R829388 (Final) |
Exit Exit |
|
Yang T, Allen PD, Pessah IN, Lopez JR. Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations. Journal of Biological Chemistry 2007;282(52):37471-37478. |
R833292 (2007) R833292 (Final) R829388 (Final) |
Exit Exit Exit |
|
Zerbo O, Iosif AM, Delwiche L, Walker C, Hertz-Picciotto I. Month of conception and risk of autism. Epidemiology 2011;22(4):469-475. |
R833292 (2011) R833292 (Final) R829388 (Final) |
Exit Exit |
|
Zhang X, Lv CC, Tian J, Miao RJ, Xi W, Hertz-Picciotto I, Qi L. Prenatal and perinatal risk factors for autism in China. Journal of Autism and Developmental Disorders 2010;40(11):1311-1321. |
R833292 (2009) R833292 (Final) |
Exit Exit Exit |
|
Zivkovic AM, German JB, Esfandiari F, Halsted CH. Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease. Alcoholism: Clinical & Experimental Research 2009;33(4):751-758. |
R833292 (Final) |
Exit |
|
Zivkovic AM, Wiest MM, Nguyen U, Nording ML, Watkins SM, German JB. Assessing individual metabolic responsiveness to a lipid challenge using a targeted metabolomic approach. Metabolomics 2009;5(2):209-218. |
R833292 (Final) |
Exit |
|
Zivkovic AM, German JB. Metabolomics for assessment of nutritional status. Current Opinion in Clinical Nutrition and Metabolic Care 2009;12(5):501-507. |
R833292 (Final) |
Exit |
|
Zivkovic AM, Telis N, German JB, Hammock BD. Dietary omega-3 fatty acids in the modulation of inflammation and metabolic health. California Agriculture 2011;65(3):106-111. |
R833292 (Final) |
Exit Exit Exit |
|
Zivkovic AM, German JB, Lebrilla CB, Mills DA. Human milk glycobiome and its impact on the infant gastrointestinal microbiota. Proceedings of the National Academy of Sciences of the United States of America 2011;108(Suppl 1):4653-4658. |
R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Zivkovic AM, Barile D. Bovine milk as a source of functional oligosaccharides for improving human health. Advances in Nutrition 2011;2(3):284-289. |
R833292 (2012) R833292 (Final) |
Exit Exit Exit |
|
Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR. Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak. Proceedings of the National Academy of Sciences of the United States of America2011;108(17):7046-7051. |
R833292 (2012) |
Exit Exit Exit |
|
Nordahl CW, Lange N, Li DD, Barnett LA, Lee A, Buonocore MH, Simon TJ, Rogers S, Ozonoff S, Amaral DG. Brain enlargement is associated with regression in preschool-age boys with autism spectrum disorders. Proceedings of the National Academy of Sciences of the United States of America 2011;108(50):20195-20200. |
R833292 (2012) |
Exit Exit Exit |
|
Shumway S, Thurm A, Swedo SE, Deprey L, Barnett LA, Amaral DG, Rogers SJ, Ozonoff S. Brief report: symptom onset patterns and functional outcomes in young children with autism spectrum disorders. Journal of Autism and Developmental Disorders 2011;41(12):1727-1732. |
R833292 (2012) |
Exit |
|
Cunningham CL, Martinez Cerdeno V, Navarro Porras E, Prakash AN, Angelastro JM, Willemsen R, Hagerman PJ, Pessah IN, Berman RF, Noctor SC. Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development. Human Molecular Genetics 2011;20(1):64-79. |
R833292 (2012) |
Exit Exit Exit |
|
Jusko TA, De Roos AJ, Schwartz SM, Lawrence BP, Palkovicova L, Nemessanyi T, Drobna B, Fabisikova A, Kocan A, Jahnova E, Kavanagh TJ, Trnovec T, Hertz-Picciotto I. Maternal and early postnatal polychlorinated biphenyl exposure in relation to total serum immunoglobulin concentrations in 6-month-old infants. Journal of Immunotoxicology 2011;8(1):95-100. |
R833292 (2012) |
Exit |
|
Ghosh R, Amirian E, Dostal M, Sram RJ, Hertz-Picciotto I. Indoor coal use and early childhood growth. Archives of Pediatrics & Adolescent Medicine 2011;165(6):492-497. |
R833292 (2012) |
Exit Exit |
|
Hunsaker MR, Greco CM, Tassone F, Berman RF, Willemsen R, Hagerman RJ, Hagerman PJ. Rare intranuclear inclusions in the brains of 3 older adult males with fragile X syndrome: implications for the spectrum of fragile X-associated disorders. Journal of Neuropathology & Experimental Neurology 2011;70(6):462-469. |
R833292 (2012) |
Exit |
|
Rozga A, Hutman T, Young GS, Rogers SJ, Ozonoff S, Dapretto M, Sigman M. Behavioral profiles of affected and unaffected siblings of children with autism: contribution of measures of mother-infant interaction and nonverbal communication. Journal of Autism and Developmental Disorders 2011;41(3):287-301. |
R833292 (2012) |
Exit Exit Exit |
|
Bent S, Bertoglio K, Ashwood P, Bostrom A, Hendren RL. A pilot randomized controlled trial of omega-3 fatty acids for autism spectrum disorder. Journal of Autism Developmental Disorders 2011;41(5):545-554. |
R833292 (2012) |
Exit Exit Exit |
|
Bookman EB, McAllister K, Gillanders E, Wanke K, Balshaw D, Rutter J, Reedy J, Shaughnessy D, Agurs-Collins T, Paltoo D, Atienza A, Bierut L, Kraft P, Fallin MD, Perera F, Turkheimer E, Boardman J, Marazita ML, Rappaport SM, Boerwinkle E, Suomi SJ, Caporaso NE, Hertz-Picciotto I, Jacobson KC, Lowe WL, Goldman LR, Duggal P, Gunnar MR, Manolio TA, Green ED, Olster DH, Birnbaum LS for the NIH G × E Interplay Workshop participants. Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop. Genetic Epidemiology 2011;35(4):217-225. |
R833292 (2012) |
Exit |
|
Vivanti G, McCormick C, Young GS, Abucayan F, Hatt N, Nadig A, Ozonoff S, Rogers SJ. Intact and impaired mechanisms of action understanding in autism. Developmental Psychology 2011;47(3):841-856. |
R833292 (2012) |
Exit |
|
Hallmayer J, Cleveland S, Torres A, Phillips J, Cohen B, Torigoe T, Miller J, Fedele A, Collins J, Smith K, Lotspeich L, Croen LA, Ozonoff S, Lajonchere C, Grether JK, Risch N. Genetic heritability and shared environmental factors among twin pairs with autism. JAMA Psychiatry (formerly Archives of General Psychiatry). 2011;68(11):1095-1102. |
R833292 (2012) |
Exit Exit |
|
Young GS, Rogers SJ, Hutman T, Rozga A, Sigman M, Ozonoff S. Imitation from 12 to 24 months in autism and typical development: a longitudinal Rasch analysis. Developmental Psychology 2011;47(6):1565-1578. |
R833292 (2012) |
Exit |
|
Critchfield JW, van Hemert S, Ash M, Mulder L, Ashwood P. The potential role of probiotics in the management of childhood autism spectrum disorders. Gastroenterology Research and Practice 2011;2011:161358 (8 pp.). |
R833292 (2012) |
Exit Exit |
|
Hunsaker MR, Greco CM, Spath MA, Smits AP, Navarro CS, Tassone F, Kros JM, Severijnen LA, Berry-Kravis EM, Berman RF, Hagerman PJ, Willemsen R, Hagerman RJ, Hukema RK. Widespread non-central nervous system organ pathology in fragile X premutation carriers with fragile X-associated tremor/ataxia syndrome and CGG knock-in mice. Acta Neuropathologica 2011;122(4):467-479. |
R833292 (2012) |
Exit |
|
Hunsaker MR, von Leden RE, Ta BT, Goodrich-Hunsaker NJ, Arque G, Kim K, Willemsen R, Berman RF. Motor deficits on a ladder rung task in male and female adolescent and adult CGG knock-in mice. Behavioural Brain Research 2011;222(1):117-121. |
R833292 (2012) |
Exit Exit Exit |
|
Ozonoff S, Young GS, Carter A, Messinger D, Yirmiya N, Zwaigenbaum L, Bryson S, Carver LJ, Constantino JN, Dobkins K, Hutman T, Iverson JM, Landa R, Rogers SJ, Sigman M, Stone WL. Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium study. Pediatrics 2011;128(3):e488-e495. |
R833292 (2012) |
Exit Exit Exit |
|
Dutta SK, Mitra PS, Ghosh S, Zang S, Sonneborn D, Hertz-Picciotto I, Trnovec T, Palkovicova L, Sovcikova E, Ghimbovschi S, Hoffman EP. Differential gene expression and a functional analysis of PCB-exposed children: understanding disease and disorder development. Environment International 2012;40:143-154. |
R833292 (2012) |
Exit Exit Exit |
|
Jusko TA, Sonneborn D, Palkovicova L, Kocan A, Drobna B, Trnovec T, Hertz-Picciotto I. Pre- and postnatal polychlorinated biphenyl concentrations and longitudinal measures of thymus volume in infants. Environmental Health Prespectives 2012;120(4):595-600. |
R833292 (2012) |
|
|
van Thriel C, Westerink RH, Beste C, Bale AS, Lein PJ, Leist M. Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts. Neurotoxicology 2012;33(4):911-924. |
R833292 (2012) |
Exit Exit Exit |
|
Ghosh R, Joad J, Benes I, Dostal M, Sram RJ, Hertz-Picciotto I. Ambient nitrogen oxides exposure and early childhood respiratory illnesses. Environment International 2012;39(1):96-102. |
R833292 (2012) |
Exit Exit Exit |
|
Mitra PS, Ghosh S, Zang S, Sonneborn D, Hertz-Picciotto I, Trnovec T, Palkovicova L, Sovcikova E, Ghimbovschi S, Hoffman EP, Dutta SK. Analysis of the toxicogenomic effects of exposure to persistent organic pollutants (POPs) in Slovakian girls: correlations between gene expression and disease risk. Environment International 2012;39(1):188-199. |
R833292 (2012) |
Exit Exit Exit |
|
Barrientos GC, Feng W, Truong K, Matthaei KI, Yang T, Allen PD, Lopez JR, Pessah IN. Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826I-RYR1 malignant hyperthermia-susceptible muscle. The Journal of Biological Chemistry 2012;287(4):2863-2876. |
R833292 (2012) |
Exit Exit Exit |
|
Cao Z, Hulsizer S, Tassone F, Tang HT, Hagerman RJ, Rogawski MA, Hagerman PJ, Pessah IN. Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. Human Molecular Genetics 2012;21(13):2923-2935. |
R833292 (2012) |
Exit Exit Exit |
|
Borthwell RM, Hunsaker MR, Willemsen R, Berman RF. Spatiotemporal processing deficits in female CGG KI mice modeling the fragile X premutation. Behavioural Brain Research 2012;233(1):29-34. |
R833292 (2012) |
Exit Exit Exit |
|
Bent S, Bertoglio K, Ashwood P, Nemeth E, Hendren RL. Brief report: hyperbaric oxygen therapy (HBOT) in children with autism spectrum disorder: a clinical trial. Journal of Autism Developmental Disorders 2012;42(6):1127-1132. |
R833292 (2012) |
Exit |
|
Lein PJ. Emerging concepts in neurotoxicology: models, mechanisms and modifying factors. NeuroToxicology 2012;33(3):516-517. |
R833292 (2012) |
Exit Exit Exit |
|
Yuen B, Boncompagni S, Feng W, Yang T, Lopez JR, Matthaei KI, Goth SR, Protasi F, Franzini-Armstrong C, Allen PD, Pessah IN. Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage. FASEB Journal 2012;26(3):1311-1322. |
R833292 (2012) |
Exit Exit Exit |
|
Schebb NH, Ahn KC, Dong H, Gee SJ, Hammock BD. Whole blood is the sample matrix of choice for monitoring systemic triclocarban levels. Chemosphere 2012;87(7):825-827. |
R833292 (2012) |
Exit Exit Exit |
|
Braunschweig D, Golub MS, Koenig CM, Qi L, Pessah IN, Van de Water J, Berman RF. Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model. Journal of Neuroimmunology 2012;15;252(1-2):56-65. |
R833292 (2012) |
Exit |
|
Kaplan ES, Cao Z, Hulsizer S, Tassone F, Berman RF, Hagerman PJ, Pessah IN. Early mitochondrial abnormalities in hippocampal neurons cultured from Fmr1 pre-mutation mouse model. Journal of Neurochemistry 2012;123(4):613-621. |
R833292 (2012) |
Exit Exit Exit |
|
Ozonoff S. Editorial perspective: autism spectrum disorders in DSM-5--an historical perspective and the need for change. Journal of Child Psychology and Psychiatry 2012;53(10):1092-1094. |
R833292 (2012) |
Exit Exit Exit |
|
Winarni TI, Chonchaiya W, Sumekar TA, Ashwood P, Morales GM, Tassone F, Nguyen DV, Faradz SM, Van de Water J, Cook K, Hamlin A, Mu Y, Hagerman PJ, Hagerman RJ. Immune-mediated disorders among women carriers of fragile X premutation alleles. American Journal of Medical Genetics Part A 2012;158A(10):2473-2481. |
R833292 (2012) |
Exit |
|
Kim IH, Nishi K, Kasagami T, Morisseau C, Liu JY, Tsai HJ, Hammock BD. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry Letters 2012;22(18):5889-5892. |
R833292 (2012) |
Exit |
|
Fatemi SH, Aldinger KA, Ashwood P, Bauman ML, Blaha CD, Blatt GJ, Chauhan A, Chauhan V, Dager SR, Dickson PE, Estes AM, Goldowitz D, Heck DH, Kemper TL, King BH, Martin LA, Millen KJ, Mittleman G, Mosconi MW, Persico AM, Sweeney JA, Webb SJ, Welsh JP. Consensus paper: pathological role of the cerebellum in autism. Cerebellum 2012;11(3):777-807. |
R833292 (2012) |
Exit |
|
Ozonoff S. DSM-5 and autism spectrum disorders--two decades of perspectives from the JCPP. Journal of Child Psychology and Psychiatry 2012;53(9):e4-e6 (editorial). |
R833292 (2012) |
Exit Exit Exit |
|
Onore C, Van de Water J, Ashwood P. Decreased levels of EGF in plasma of children with autism spectrum disorder. Autism Research and Treatment 2012;2012:205362 (4 pp.). |
R833292 (2012) |
Exit Exit Exit |
|
Clifton MS, Wargo JP, Weathers WS, Colon M, Bennett DH, Tulve NS. Quantitative analysis of organophosphate and pyrethroid insecticides, pyrethroid transformation products, polybrominated diphenyl ethers and bisphenol A in residential surface wipe samples. Journal of Chromatography A 2013;1273:1-11. |
R833292 (2012) |
Exit Exit Exit |
|
Volk HE, Lurmann F, Penfold B, Hertz-Picciotto I, McConnell R. Traffic related air pollution, particulate matter, and autism. JAMA Psychiatry 2013;70(1):71-77. |
R833292 (2012) R835441 (2017) |
Exit Exit Exit |
|
Zerbo O, Iosif A-M, Walker C, Ozonoff S, Hansen RL, Hertz-Picciotto I. Is maternal influenza or fever during pregnancy associated with autism or developmental delays? Results from the CHARGE (CHildhood Autism Risks from Genetics and Environment) Study. Journal of Autism and Developmental Disorders 2013;43(1):25-33. |
R833292 (2012) R833292 (Final) |
Exit |
|
Breece E, Paciotti B, Nordahl CW, Ozonoff S, Van de Water JA, Rogers SJ, Amaral D, Ashwood P. Myeloid dendritic cells frequencies are increased in children with autism spectrum disorder and associated with amygdala volume and repetitive behaviors. Brain, Behavior, and Immunity 2013;31:69-75. |
R833292 (2012) |
Exit Exit Exit |
|
Tassone F, Choudhary NS, Tassone F, Durbin-Johnson B, Hansen R, Hertz-Picciotto I, Pessah I. Identification of expanded alleles of the FMR1 gene in the CHildhood Autism Risks from Genes and Environment (CHARGE) study. Journal of Autism and Developmental Disorders 2013;43(3):530-539. |
R833292 (2012) |
Exit |
|
Goines PE, Ashwood P. Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment. Neurotoxicology and Teratology 2013;36:67-81. |
R833292 (2012) |
Exit Exit Exit |
|
Schwartzer JJ, Koenig CM, Berman RF. Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions. Neurotoxicology and Teratology 2013;36:17-35. |
R833292 (2012) |
Exit Exit Exit |
|
Hertz-Picciotto I, Schmidt RJ, Walker CK, Bennett DH, Oliver M, Shedd-Wise KM, LaSalle JM, Giulivi C, Puschner B, Thomas J, Roa DL. A prospective study of environmental exposures and early biomarkers in autism spectrum disorder:design, protocols, and preliminary data from the MARBLES study. Environmental Health Perspectives 2018;126(11):117004. doi:10.1289/EHP535. |
R833292 (Final) R829388 (Final) |
|
|
Zheng J, Yu Y, Feng W, Li J, Liu J, Zhang C, Dong Y, Pessah IN, Cao Z. Influence of nanomolar deltamethrin on the hallmarks of primary cultured cortical neuronal network and the role of ryanodine receptors. Environmental Health Perspectives 2019;127(6):67003 |
R833292 (Final) R829388 (Final) |
|
Supplemental Keywords:
autism, genes, environment, mercury, PCBs, PBDEs, immune, autoimmune, neurodevelopment, developmental neurotoxicity, persistent organic pollutants, CHARGE, MARBLES,, Health, Scientific Discipline, Genetics, Health Risk Assessment, Risk Assessments, Biochemistry, children's health, developmental neurotoxicology, ecotoxicogenomics, developmental effects, genetic analysisProgress and Final Reports:
Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R833292C001 PROJECT 1: Environmental Epidemiology of Autism
R833292C002 PROJECT 2: Immunological Susceptibility in Autism
R833292C003 PROJECT 3: Models of Neurosusceptibility
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.
Project Research Results
- Final Report
- 2012 Progress Report
- 2011 Progress Report
- 2010 Progress Report
- 2009 Progress Report
- 2008 Progress Report
- 2007 Progress Report
293 journal articles for this center