Grantee Research Project Results
Selected Publications Details for Grant Number R832416C001
Cardiovascular Responses in the Normative Aging Study: Exploring the Pathways of Particle Toxicity
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Journal Article | Alexeeff SE, Litonjua AA, Suh H, Sparrow D, Vokonas PS, Schwartz J. Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA Normative Aging Study. Chest 2007;132(6):1890-1897. |
R827353 (Final) R832416 (2006) R832416 (2009) R832416 (Final) R832416C001 (2008) R832416C001 (2009) R832416C001 (Final) |
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| Journal Article | Alexeeff SE, Litonjua AA, Sparrow D, Vokonas PS, Schwartz J. Statin use reduces decline in lung function: VA Normative Aging Study. American Journal of Respiratory and Critical Care Medicine 2007;176(8):742-747. |
R827353 (Final) R832416 (2006) R832416 (Final) R832416C001 (2008) R832416C001 (Final) |
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| Journal Article | Alexeeff SE, Litonjua AA, Wright RO, Baccarelli A, Suh H, Sparrow D, Vokonas PS, Schwartz J. Ozone exposure, antioxidant genes, and lung function in an elderly cohort:VA Normative Aging Study. Occupational and Environmental Medicine 2008;65(11):736-742. |
R827353 (Final) R832416 (Final) R832416C001 (2008) R832416C001 (Final) |
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| Journal Article | Alexeeff SE, Coull BA, Gyparis A, Suh H, Sparrow D, Vokonas PS, Schwartz J. Medium-term exposure to traffic-related air pollution and markers of inflammation and endothelial function. Environmental Health Perspectives 2011;119(4):481-486. |
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| Journal Article | Baccarelli A, Cassano PA, Litonjua A, Park SK, Suh H, Sparrow D, Vokonas P, Schwartz J. Cardiac autonomic dysfunction: effects from particulate air pollution and protection by dietary methyl nutrients and metabolic polymorphisms. Circulation 2008;117(14):1802-1809. |
R827353 (Final) R832416 (2006) R832416 (Final) R832416C001 (2008) R832416C001 (Final) |
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| Journal Article | Baccarelli A, Martinelli I, Zanobetti A, Grillo P, Hou L-F, Bertazzi PA, Mannucci PM, Schwartz J. Exposure to particulate air pollution and risk of deep vein thrombosis. Archives of Internal Medicine 2008;168(9):920-927. |
R827353 (Final) R832416 (2006) R832416 (Final) R832416C001 (2008) R832416C001 (Final) |
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| Journal Article | Baccarelli A, Wright RO, Bollati V, Tarantini L, Litonjua AA, Suh HH, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J. Rapid DNA methylation changes after exposure to traffic particles. American Journal of Respiratory and Critical Care Medicine 2009;179(7):572-578. |
R827353 (Final) R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Baccarelli A, Martinelli I, Pegoraro V, Melly S, Grillo P, Zanobetti A, Hou L, Bertazzi PA, Mannucci PM, Schwartz J. Living near major traffic roads and risk of deep vein thrombosis. Circulation 2009;119(24):3118-3124. |
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| Journal Article | Baccarelli A, Tarantini L, Wright RO, Bollati V, Litonjua AA, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J. Repetitive element DNA methylation and circulating endothelial and inflammation markers in the VA Normative Aging Study. Epigenetics 2010;5(3):222-228. |
R827353 (Final) R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Baccarelli A, Wright R, Bollati V, Litonjua A, Zanobetti A, Tarantini L, Sparrow D, Vokonas P, Schwartz J. Ischemic heart disease and stroke in relation to blood DNA methylation. Epidemiology 2010;21(6):819-828. |
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| Journal Article | Baja ES, Schwartz JD, Wellenius GA, Coull BA, Zanobetti A, Vokonas PS, Suh HH. Traffic-related air pollution and QT interval: modification by diabetes, obesity, and oxidative stress gene polymorphisms in the Normative Aging Study. Environmental Health Perspectives 2010;118(6):840-846. |
R827353 (Final) R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Bind MA, Baccarelli A, Zanobetti A, Tarantini L, Suh H, Vokonas P, Schwartz J. Air pollution and markers of coagulation, inflammation, and endothelial function:associations of epigene-environment Interactions in an elderly cohort. Epidemiology 2012;23(2):332-340. |
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| Journal Article | Bollati V, Schwartz J, Wright R, Litonjua A, Tarantini L, Suh H, Sparrow D, Vokonas P, Baccarelli A. Decline in genomic DNA methylation through aging in a cohort of elderly subjects. Mechanisms of Ageing and Development 2009;130(4):234-239. |
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| Journal Article | Chahine T, Baccarelli A, Litonjua A, Wright RO, Suh H, Gold DR, Sparrow D, Vokonas P, Schwartz J. Particulate air pollution, oxidative stress genes, and heart rate variability in an elderly cohort. Environmental Health Perspectives 2007;115(11):1617-1622. |
R827353 (Final) R832416 (2006) R832416 (2008) R832416 (2009) R832416 (Final) R832416C001 (2008) R832416C001 (2009) R832416C001 (Final) |
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| Journal Article | Chen J-C, Schwartz J. Metabolic syndrome and inflammatory responses to long-term particulate air pollutants. Environmental Health Perspectives 2008;116(5):612-617. |
R827353 (Final) R832416 (2006) R832416 (Final) R832416C001 (Final) |
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| Journal Article | Chen J-C, Schwartz J. Neurobehavioral effects of ambient air pollution on cognitive performance in US adults. NeuroToxicology 2009;30(2):231-239. |
R827353 (Final) R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Dioni L, Hoxha M, Nordio F, Bonzini M, Tarantini L, Albetti B, Savarese A, Schwartz J, Bertazzi PA, Apostoli P, Hou L, Baccarelli A. Effects of short-term exposure to inhalable particulate matter on telomere length, telomerase expression, and telomerase methylation in steel workers. Environmental Health Perspectives 2011;119(5):622-627. |
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| Journal Article | Franklin M, Schwartz J. The impact of secondary particles on the association between ambient ozone and mortality. Environmental Health Perspectives 2008;116(4):453-458. |
R832416 (2006) R832416 (2008) R832416 (Final) R832416C001 (2008) |
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| Journal Article | Franklin M, Koutrakis P, Schwartz J. The role of particle composition on the association between PM2.5 and mortality. Epidemiology 2008;19(5):680-689. |
R832416 (2006) R832416 (2008) R832416 (Final) R832416C001 (2008) |
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| Journal Article | Gryparis A, Coull BA, Schwartz J. Controlling for confounding in the presence of measurement error in hierarchical models: a Bayesian approach. Journal of Exposure Science & Environmental Epidemiology 2007;17(Suppl 2):S20-S28. |
R832416 (2008) R832416 (Final) R832416C001 (2008) |
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| Journal Article | Gryparis A, Paciorek CJ, Zeka A, Schwartz J, Coull BA. Measurement error caused by spatial misalignment in environmental epidemiology. Biostatistics 2009;10(2):258-274. |
R832416 (2008) R832416 (Final) R832416C001 (2010) |
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| Journal Article | Halonen JI, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J. Associations between outdoor temperature and markers of inflammation:a cohort study. Environmental Health 2010;9:42 (9 pp.). |
R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Halonen JI, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J. Relationship between outdoor temperature and blood pressure. Occupational and Environmental Medicine 2011;68(4):296-301. |
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| Journal Article | Hoffmann B, Luttmann-Gibson H, Cohen A, Zanobetti A, de Souza C, Foley C, Suh HH, Coull BA, Schwartz J, Mittleman M, Stone P, Horton E, Gold DR. Opposing effects of particle pollution, ozone, and ambient temperature on arterial blood pressure. Environmental Health Perspectives 2012;120(2):241-246. |
R832416 (Final) R832416C001 (Final) R834798 (2012) R834798 (2013) R834798 (2014) R834798 (2015) R834798 (Final) R834798C001 (2014) R834798C002 (Final) R834798C004 (2012) R834798C004 (2014) R834798C004 (Final) |
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| Journal Article | Hoxha M, Dioni L, Bonzini M, Pesatori AC, Fustinoni S, Cavallo D, Carugno M, Albetti B, Marinelli B, Schwartz J, Bertazzi PA, Baccarelli A. Association between leukocyte telomere shortening and exposure to traffic pollution:a cross-sectional study on traffic officers and indoor office workers. Environmental Health 2009;8:41. |
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| Journal Article | Levy JI, Diez D, Dou Y, Barr CD, Dominici F. A meta-analysis and multisite time-series analysis of the differential toxicity of major fine particulate matter constituents. American Journal of Epidemiology 2012;175(11):1091-1099. |
R832416C001 (Final) R832417 (Final) R834798 (2012) R834798 (2013) R834798 (2014) R834798 (2015) R834798 (Final) R834798C001 (2014) R834798C005 (2012) R834798C005 (Final) R834894 (2012) R834894 (2013) |
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| Journal Article | Madrigano J, Baccarelli A, Wright RO, Suh H, Sparrow D, Vokonas PS, Schwartz J. Air pollution, obesity, genes and cellular adhesion molecules. Occupational and Environmental Medicine 2010;67(5):312-317. |
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| Journal Article | Madrigano J, Baccarelli A, Mittleman MA, Wright RO, Sparrow D, Vokonas PS, Tarantini L, Schwartz J. Prolonged exposure to particulate pollution, genes associated with glutathione pathways, and DNA methylation in a cohort of older men. Environmental Health Perspectives 2011;119(7):977-982. |
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| Journal Article | Maynard D, Coull BA, Gryparis A, Schwartz J. Mortality risk associated with short-term exposure to traffic particles and sulfates. Environmental Health Perspectives 2007;115(5):751-755. |
R827353 (Final) R827355 (Final) R832416 (2008) R832416 (2009) R832416C001 (2009) |
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| Journal Article | McCracken JP, Smith KR, Diaz A, Mittleman MA, Schwartz J. Chimney stove intervention to reduce long-term wood smoke exposure lowers blood pressure among Guatemalan women. Environmental Health Perspectives 2007;115(7):996-1001. |
R827353 (Final) R832416C001 (2008) |
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| Journal Article | McCracken J, Baccarelli A, Hoxha M, Dioni L, Melly S, Coull B, Suh H, Vokonas P, Schwartz J. Annual ambient black carbon associated with shorter telomeres in elderly men: Veterans Affairs Normative Aging Study. Environmental Health Perspectives 2010;118(11):1564-1570. |
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| Journal Article | McCracken J, Smith KR, Stone P, Diaz A, Arana B, Schwartz J. Intervention to lower household wood smoke exposure in Guatemala reduces ST-segment depression on electrocardiograms. Environmental Health Perspectives 2011;119(11):1562-1568. |
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| Journal Article | Medina-Ramon M, Schwartz J. Temperature, temperature extremes, and mortality:a study of acclimatisation and effect modification in 50 US cities. Occupational and Environmental Medicine 2007;64(12):827-833. |
R827353 (Final) R832416C001 (2008) |
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| Journal Article | Medina-Ramon M, Goldberg R, Melly S, Mittleman MA, Schwartz J. Residential exposure to traffic-related air pollution and survival after heart failure. Environmental Health Perspectives 2008;116(4):481-485. |
R832416 (2006) R832416 (2008) R832416 (Final) R832416C001 (2008) R832416C001 (Final) |
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| Journal Article | Medina-Ramon M, Schwartz J. Who is more vulnerable to die from ozone air pollution? Epidemiology 2008;19(5):672-679. |
R827353 (Final) R832416C001 (2008) |
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| Journal Article | Mordukhovich I, Wilker E, Suh H, Wright R, Sparrow D, Vokonas PS, Schwartz J. Black carbon exposure, oxidative stress genes, and blood pressure in a repeated-measures study. Environmental Health Perspectives 2009;117(11):1767-1772. |
R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Park SK, O'Neill MS, Vokonas PS, Sparrow D, Schwartz J. Effects of air pollution on heart rate variability: the VA Normative Aging Study. Environmental Health Perspectives 2005;113(3):304-309. |
R827353 (Final) R827353C010 (Final) R831076 (Final) R832416 (2009) R832416C001 (2009) |
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| Journal Article | Park SK, O'Neill MS, Wright RO, Hu H, Vokonas PS, Sparrow D, Suh H, Schwartz J. HFE genotype, particulate air pollution, and heart rate variability: a gene-environment interaction. Circulation 2006;114(25):2798-2805. |
R827353 (Final) R827353C010 (Final) R831076 (Final) R832416 (2009) R832416C001 (2009) |
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| Journal Article | Park SK, O'Neill MS, Stunder BJ, Vokonas PS, Sparrow D, Koutrakis P, Schwartz J. Source location of air pollution and cardiac autonomic function: trajectory cluster analysis for exposure assessment. Journal of Exposure Science & Environmental Epidemiology 2007;17(5):488-497. |
R827353 (Final) R827353C010 (Final) R831076 (Final) R832416 (2008) R832416 (2009) R832416C001 (2009) |
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| Journal Article | Park SK, O’Neill MS, Vokonas PS, Sparrow D, Spiro III A, Tucker KL, Suh H, Hu H, Schwartz J. Traffic-related particles are associated with elevated homocysteine: the VA Normative Aging Study. American Journal of Respiratory and Critical Care Medicine 2008;178(3):283-289. |
R827353 (Final) R832416 (2006) R832416 (2009) R832416 (Final) R832416C001 (2008) R832416C001 (2009) R832416C001 (Final) |
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| Journal Article | Park SK, O’Neill MS, Vokonas PS, Sparrow D, Wright RO, Coull B, Nie H, Hu H, Schwartz J. Air pollution and heart rate variability: effect modification by chronic lead exposure. Epidemiology 2008;19(1):111-120. |
R827353 (Final) R832416 (2006) R832416 (2009) R832416 (Final) R832416C001 (2008) R832416C001 (2009) R832416C001 (Final) |
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| Journal Article | Park SK, Tucker KL, O'Neill MS, Sparrow D, Vokonas PS, Hu H, Schwartz J. Fruit, vegetable, and fish consumption and heart rate variability: the Veterans Administration Normative Aging Study. American Journal of Clinical Nutrition 2009;89(3):778-786. |
R827353 (Final) R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Peters JL, Kubzansky LD, Ikeda A, Spiro III A, Wright RO, Weisskopf MG, Kim D, Sparrow D, Nie LH, Hu H, Schwartz J. Childhood and adult socioeconomic position, cumulative lead levels, and pessimism in later life: the VA Normative Aging Study. American Journal of Epidemiology 2011;174(12):1345-1353. |
R832416 (Final) R832416C001 (Final) R834798 (2010) R834798 (2011) R834798 (2014) R834798 (2015) R834798 (Final) R834798C001 (2014) R834798C001 (Final) R834798C002 (2010) R834798C002 (2011) R834798C002 (2014) R834798C002 (Final) |
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| Journal Article | Peters JL, Kubzansky LD, Ikeda A, Fang SC, Sparrow D, Weisskopf MG, Wright RO, Vokonas P, Hu H, Schwartz J. Lead concentrations in relation to multiple biomarkers of cardiovascular disease: the Normative Aging Study. Environmental Health Perspectives 2012;120(3):361-366. |
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| Journal Article | Ren C, Vokonas PS, Suh H, Fang S, Christiani DC, Schwartz J. Effect modification of air pollution on urinary 8-hydroxy-2'-deoxyguanosine by genotypes: an application of the multiple testing procedure to identify significant SNP interactions. Environmental Health 2010;9:78 (9 pp.). |
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| Journal Article | Ren C, Melly S, Schwartz J. Modifiers of short-term effects of ozone on mortality in eastern Massachusetts—a case-crossover analysis at individual level. Environmental Health 2010;9:3 (10 pp.). |
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| Journal Article | Ren C, Baccarelli A, Wilker E, Suh H, Sparrow D, Vokonas P, Wright R, Schwartz J. Lipid and endothelium-related genes, ambient particulate matter, and heart rate variability—the VA Normative Aging Study. Journal of Epidemiology and Community Health 2010;64(1):49-56. |
R827353 (Final) R832416 (2009) R832416 (Final) R832416C001 (2009) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Ren C, Park SK, Vokonas PS, Sparrow D, Wilker E, Baccarelli A, Suh HH, Tucker KL, Wright RO, Schwartz J. Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution. Epidemiology 2010;21(2):198-206. |
R827353 (Final) R832416 (2009) R832416 (Final) R832416C001 (2009) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Ren C, Fang S, Wright RO, Suh H, Schwartz J. Urinary 8-hydroxy-2'-deoxyguanosine as a biomarker of oxidative DNA damage induced by ambient pollution in the Normative Aging Study. Occupational and Environmental Medicine 2011;68(8):562-569. |
R832416 (2009) R832416C001 (2009) |
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| Journal Article | Ren C, O'Neill MS, Park SK, Sparrow D, Vokonas P, Schwartz J. Ambient temperature, air pollution, and heart rate variability in an aging population. American Journal of Epidemiology 2011;173(9):1013-1021. |
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| Journal Article | Schwartz J, Sarnat JA, Coull BA, Wilson WE. Effects of exposure measurement error on particle matter epidemiology:a simulation using data from a panel study in Baltimore, MD. Journal of Exposure Science and Environmental Epidemiology 2007;17(Suppl 2):S2-S10. |
R832416 (2008) R832416 (Final) R832416C001 (2008) R832416C001 (Final) |
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| Journal Article | Schwartz J, Coull B, Laden F, Ryan L. The effect of dose and timing of dose on the association between airborne particles and survival. Environmental Health Perspectives 2008;116(1):64-69. |
R832416 (2006) R832416 (2008) R832416 (Final) R832416C001 (2008) |
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| Journal Article | Stafoggia M, Schwartz J, Forastiere F, Perucci CA, the SISTI Group. Does temperature modify the association between air pollution and mortality? A multicity case-crossover analysis in Italy. American Journal of Epidemiology 2008;167(12):1476-1485. |
R832416C001 (2008) |
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| Journal Article | Wellenius GA, Yeh GY, Coull BA, Suh HH, Phillips RS, Mittleman MA. Effects of ambient air pollution on functional status in patients with chronic congestive heart failure: a repeated-measures study. Environmental Health 2007;6:26. |
R827353 (Final) R832416 (2006) R832416 (Final) R832416C001 (Final) |
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| Journal Article | Wilker EH, Alexeeff SE, Poon A, Litonjua AA, Sparrow D, Vokonas PS, Mittleman MA, Schwartz J. Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men. Atherosclerosis 2009;206(2):480-485. |
R832416 (2009) R832416 (Final) R832416C001 (2009) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Wilker EH, Baccarelli A, Suh H, Vokonas P, Wright RO, Schwartz J. Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in microRNA processing genes. Environmental Health Perspectives 2010;118(7):943-948. |
R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Wilker EH, Alexeeff SE, Suh H, Vokonas PS, Baccarelli A, Schwartz J. Ambient pollutants, polymorphisms associated with microRNA processing and adhesion molecules:the Normative Aging Study. Environmental Health 2011;10:45. |
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| Journal Article | Wilker E, Mittleman MA, Litonjua AA, Poon A, Baccarelli A, Suh H, Wright RO, Sparrow D, Vokonas P, Schwartz J. Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter. Environmental Health Perspectives 2009;117(6):935-940. |
R827353 (Final) R832416 (Final) R832416C001 (2010) R832416C001 (Final) |
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| Journal Article | Zanobetti A, Schwartz J. Is there adaptation in the ozone mortality relationship:a multi-city case-crossover analysis. Environmental Health 2008;7:22 (6 pp.). |
R832416 (2006) R832416 (2008) R832416 (Final) R832416C001 (2008) |
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| Journal Article | Zanobetti A, Franklin M, Koutrakis P, Schwartz J. Fine particulate air pollution and its components in association with cause-specific emergency admissions. Environmental Health 2009;8:58 (12 pp.). |
R832416 (Final) R832416C001 (2010) |
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| Journal Article | Zanobetti A, Schwartz J. The effect of fine and coarse particulate air pollution on mortality: a national analysis. Environmental Health Perspectives 2009;117(6):898-903. |
R832416 (Final) R832416C001 (2010) |
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| Journal Article | Zanobetti A, Stone PH, Speizer FE, Schwartz JD, Coull BA, Suh HH, Nearing BD, Mittleman MA, Verrier RL, Gold DR. T-wave alternans, air pollution and traffic in high-risk subjects. American Journal of Cardiology 2009;104(5):665-670. |
R832416 (Final) R832416C001 (2010) |
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| Journal Article | Zanobetti A, Baccarelli A, Schwartz J. Gene-air pollution interaction and cardiovascular disease: a review. Progress in Cardiovascular Diseases 2011;53(5):344-352. |
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| Journal Article | Zanobetti A, Schwartz J. Ozone and survival in four cohorts with potentially predisposing diseases. American Journal of Respiratory and Critical Care Medicine 2011;184(7):836-841. |
R832416 (Final) R832416C001 (Final) R834798 (2010) R834798 (2011) R834798 (2013) R834798 (2014) R834798 (2015) R834798 (Final) R834798C001 (2014) R834798C001 (Final) R834798C002 (2010) R834798C002 (2011) R834798C002 (2014) R834798C002 (Final) R834798C005 (Final) |
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| Journal Article | Zeka A, Sullivan JR, Vokonas PS, Sparrow D, Schwartz J. Inflammatory markers and particulate air pollution:characterizing the pathway to disease. International Journal of Epidemiology 2006;35(5):1347-1354. |
R827353 (Final) R827353C004 (Final) R827353C010 (Final) R832416 (2008) R832416 (2009) R832416C001 (2009) |
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| Journal Article | Zhu ZZ, Sparrow D, Hou L, Tarantini L, Bollati V, Litonjua AA, Zanobetti A, Vokonas P, Wright RO, Baccarelli A, Schwartz J. Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study. Cancer Causes & Control 2011;22(3):437-447. |
R827353 (Final) R832416 (Final) R832416C001 (Final) |
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| Journal Article | Zhu ZZ, Hou L, Bollati V, Tarantini L, Marinelli B, Cantone L, Yang AS, Vokonas P, Lissowska J, Fustinoni S, Pesatori AC, Bonzini M, Apostoli P, Costa G, Bertazzi PA, Chow WH, Schwartz J, Baccarelli A. Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis. International Journal of Epidemiology 2012;41(1):126-139. |
R827353 (Final) R832416 (Final) R832416C001 (Final) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.