Grantee Research Project Results
Publications Details for Grant Number R834798C003
Identifying the Cognitive and Vascular Effects of Air Pollution Sources and Mixtures in the Framingham Offspring and Third Generation Cohorts
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Reference Type | Citation | Progress Report Year | Document Sources |
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Journal Article | Dorans KS, Wilker EH, Li W, et al. Residential proximity to major roads, exposure to fine particulate matter and aortic calcium:The Framingham Heart Study, a cohort study. BMJ open. 2017;7:e013455. |
R834798C003 (Final) |
not available |
Journal Article | Gold DR, Mittleman MA. New insights into pollution and the cardiovascular system: 2010 to 2012. Circulation 2013;127(18):1903-1913. |
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Journal Article | Ljungman PL, Wilker EH, Rice MB, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Mittleman MA, Hamburg NM. Short-term exposure to air pollution and digital vascular function. American Journal of Epidemiology 2014;180(5):482-489. |
R834798 (Final) R834798C003 (2014) R834798C004 (2014) |
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Journal Article | Ljungman PL, Mittleman MA. Ambient air pollution and stroke. Stroke. 2014b;45:3734-3741. |
R834798C003 (Final) |
not available |
Journal Article | Lue S-H, Wellenius GA, Wilker EH, Mostofsky E, Mittleman MA. Residential proximity to major roadways and renal function. Journal of Epidemiology & Community Health 2013;67(8):629-634. |
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Journal Article | Mittleman MA, Mostofsky E. Exchangeability in the case-crossover design. International Journal of Epidemiology 2014;43(5):1645-1655. |
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Journal Article | Mostofsky E, Wilker EH, Schwartz J, Zanobetti A, Gold DR, Wellenius GA, Mittleman MA. Short-term changes in ambient temperature and risk of ischemic stroke. Cerebrovascular Diseases Extra 2014;4(1):9-18. |
R834798 (2014) R834798 (Final) R834798C003 (2014) R834798C003 (Final) R834798C004 (2014) |
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Journal Article | Mostofsky, E., Schwartz, J., Coull, B., Koutrakis, P., Wellenius, G.A., Suh, H.H., Gold, D.R., and Mittleman, M.A. (2012). Modeling the Association between Particle Constituents of Air Pollution and Health Outcomes. American Journal of Epidemiology 176, 317 – 326. |
R834798C002 (Final) R834798C003 (Final) |
not available |
Journal Article | Rice MB, Ljungman PL, Wilker EH, Gold DR, Schwartz JD, Koutrakis P, Washko GR, O'Connor GT, Mittleman MA. Short-term exposure to air pollution and lung function in the Framingham Heart Study. American Journal of Respiratory and Critical Care Medicine 2013;188(11):1351-1357. |
R832416 (Final) R834798 (Final) R834798C003 (2014) R834798C003 (Final) |
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Journal Article | Rice MB, Thurston GD, Balmes JR, Pinkerton KE. Climate change. A global threat to cardiopulmonary health. American Journal of Respiratory and Critical Care Medicine 2014;189(5):512-519. |
R834798 (Final) R834798C003 (2014) |
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Journal Article | Rosenbloom JI, Wilker EH, Mukamal KJ, Schwartz J, Mittleman MA. Residential proximity to major roadway and 10-year all-cause mortality after myocardial infarction. Circulation 2012;125(18):2197-2203. |
R834798 (2012) R834798 (2013) R834798 (2014) R834798 (Final) R834798C003 (2012) R834798C003 (2013) R834798C003 (2014) R834798C003 (Final) |
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Journal Article | Wang Y, Eliot MN, Koutrakis P, Gryparis A, Schwartz JD, Coull BA, Mittleman MA, Milberg WP, Lipsitz LA, Wellenius GA. Ambient air pollution and depressive symptoms in older adults: results from the MOBILIZE Boston Study. Environmental Health Perspectives 2014;122(6):553-558. |
R834798 (Final) R834798C002 (2014) R834798C002 (Final) R834798C003 (2014) |
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Journal Article | Wang Y, Eliot MN, Kuchel GA, Schwartz J, Coull BA, Mittleman MA, Lipsitz LA, Wellenius GA. Long-term exposure to ambient air pollution and serum leptin in older adults: results from the MOBILIZE Boston Study. Journal of Occupational and Environmental Medicine 2014;56(9):e73-e77. |
R834797 (2016) R834798 (Final) R834798C002 (2014) R834798C002 (Final) R834798C003 (Final) |
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Journal Article | Wang, Y., Eliot, M.N., Koutrakis, P., Gryparis, A., Schwartz, J.D., Coull, B.A., Mittleman, M.A., Milberg, W.P., Lipsitz, L.A., and Wellenius, G.A. (2014). Ambient Air Pollution and Depressive Symptoms in Older Adults:Results from the MOBILIZE Boston Study. Environmental Health Perspectives 122, 553 – 558. |
R834798C003 (Final) |
not available |
Journal Article | Wellenius GA, Burger MR, Coull BA, Schwartz J, Suh HH, Koutrakis P, Schlaug G, Gold DR, Mittleman MA. Ambient air pollution and the risk of acute ischemic stroke. Archives of Internal Medicine 2012;172(3):229-234. |
R832416 (Final) R834798 (2012) R834798 (2013) R834798 (2014) R834798 (Final) R834798C003 (2012) R834798C003 (2013) R834798C003 (2014) R834798C003 (Final) |
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Journal Article | Wellenius GA, Boyle LD, Coull BA, Milberg WP, Gryparis A, Schwartz J, Mittleman MA, Lipsitz LA. Residential proximity to nearest major roadway and cognitive function in community-dwelling seniors: results from the MOBILIZE Boston Study. Journal of the American Geriatric Society 2012;60(11):2075-2080. |
R834798 (2012) R834798 (2013) R834798 (2014) R834798 (Final) R834798C003 (2013) R834798C003 (2014) |
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Journal Article | Wellenius GA, Boyle LD, Wilker EH, Sorond FA, Coull BA, Koutrakis P, Mittleman MA, Lipsitz LA. Ambient fine particulate matter alters cerebral hemodynamics in the elderly. Stroke 2013;44(6):1532-1536. |
R834797 (2016) R834797 (Final) R834797C001 (Final) R834797C002 (2016) R834797C003 (Final) R834798 (2013) R834798 (2014) R834798 (Final) R834798C002 (Final) R834798C003 (2013) R834798C003 (2014) R834798C003 (Final) |
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Journal Article | Wellenius, G.A., Boyle, L.D., Coull, B.A., Milberg, W.P., Gryparis, A., Schwartz, J., Mittleman, M.A., and Lipsitz, L.A. (2012a). Residential Proximity to Nearest Major Roadway and Cognitive Function in Community-Dwelling Seniors:Results from the MOBILIZE Boston Study. Journal of the American Geriatric Society 60, 2075–2080. |
R834798C003 (Final) |
not available |
Journal Article | Wilker EH, Yeh G, Wellenius GA, Davis RB, Phillips RS, Mittleman MA. Ambient temperature and biomarkers of heart failure: a repeated measures analysis. Environmental Health Perspectives 2012;120(8):1083-1087. |
R834798 (2012) R834798 (2013) R834798 (2014) R834798 (Final) R834798C003 (2012) R834798C003 (2013) R834798C003 (2014) |
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Journal Article | Wilker EH, Mostofsky E, Lue S-H, Gold D, Schwartz J, Wellenius GA, Mittleman MA. Residential proximity to high-traffic roadways and poststroke mortality. Journal of Stroke & Cerebrovascular Diseases 2013;22(8):e366-e372. |
R834798 (2013) R834798 (2014) R834798 (Final) R834798C003 (2013) R834798C003 (2014) R834798C003 (Final) |
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Journal Article | Wilker EH, Wu C-D, McNeely E, Mostofsky E, Spengler J, Wellenius GA, Mittleman MA. Green space and mortality following ischemic stroke. Environmental Research 2014;133:42-48. |
R834798 (2014) R834798 (Final) R834798C003 (2014) R834798C003 (Final) |
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Journal Article | Wilker EH, Ljungman PL, Rice MB, Kloog I, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Hamburg NM, Mittleman MA. Relation of long-term exposure to air pollution to brachial artery flow-mediated dilation and reactive hyperemia. American Journal of Cardiology 2014;113(12):2057-2063. |
R834798 (2014) R834798 (Final) R834798C003 (2014) R834798C003 (Final) R834798C004 (2014) R834798C004 (Final) |
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Journal Article | Wilker EH, Preis SR, Beiser AS, Wolf PA, Au R, Kloog I, Li W, Schwartz J, Koutrakis P, DeCarli C, Seshadri S, Mittleman MA. Long-term exposure to fine particulate matter, residential proximity to major roads and measures of brain structure. Stroke 2015;46(5):1161-1166. |
R834798 (2015) R834798C003 (Final) |
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Journal Article | Wilker EH, Martinez-Ramirez S, Kloog I, Schwartz J, Mostofsky E, Koutrakis P, Mittleman MA, Viswanathan A. Fine particulate matter, residential proximity to major roads, and markers of small vessel disease in a memory study population. Journal of Alzheimer's Disease 2016;53(4):1315-1323. |
R834798 (Final) R834798C003 (Final) |
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Journal Article | Ljungman PL, Wilker EH, Rice MB, et al. Short-term exposure to air pollution and digital vascular function. Am J Epidemiol. 2014a;180:482-489. |
R834798C003 (Final) R834798C004 (Final) |
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Journal Article | Dorans KS, Wilker EH, Li W, et al. Residential proximity to major roads, exposure to fine particulate matter, and coronary artery calcium:The Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2016. |
R834798C003 (Final) |
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Journal Article | Li W, Dorans KS, Wilker EH, et al. Residential proximity to major roadways, fine particulate matter, and hepatic steatosis:The Framingham Heart Study. Am J Epidemiol. 2017. |
R834798C003 (Final) |
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Journal Article | Wang, Y., Eliot, M.N., Kuchel, G.A., Schwartz, J., Coull, B.A., Mittleman, M.A., Lipsitz, L.A., and Wellenius, G.A. (2014). Long-Term Exposure to Ambient Air Pollution and. |
R834798C003 (Final) |
not available |
Journal Article | Wellenius, G.A., Wilhelm-Benartzi, C.S., Wilker, E.H., Coull, B.A., Suh, H.H., Koutrakis, P., and Lipsitz, L.A. (2012c). Ambient Particulate Matter and the Response to Orthostatic Challenge in the Elderly:The Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly (MOBILIZE) of Boston Study. Hypertension 59, 558-563. |
R834798C003 (Final) |
not available |
Journal Article | Cole, T.B., J.C. Fisher, T.M. Burbacher, L.G. Costa, and C.E. Furlong, Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon. Neurotoxicol Teratol, 2012. 34(3):p. 311-322. |
R834514C004 (Final) R834798C003 (Final) |
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Journal Article | Wilker, E.H., Yeh, G., Wellenius, G.A., Davis, R.B., Phillips, R.S., and Mittleman, M.A. (2012). Ambient Temperature and Biomarkers of Heart Failure:A Repeated Measures Analysis. Environmental Health Perspectives 120, 1083 – 1087. |
R834798C003 (Final) |
not available |
Journal Article | Serum Leptin in Older Adults:Results from the MOBILIZE Boston Study. Journal of Occupational and Environmental Medicine 56, e73-e77. |
R834798C003 (Final) |
not available |
Journal Article | Rice MB, Ljungman PL, Wilker EH, et al. Long-term exposure to traffic emissions and fine particulate matter and lung function decline in the Framingham Heart Study. Am J Respir Crit Care Med. 2015;191:656-664. |
R834798C003 (Final) R834798C004 (Final) |
not available |
Journal Article | Li W, Dorans KS, Wilker EH, et al. Residential proximity to major roadways, fine particulate matter, and adiposity:The Framingham Heart Study. Obesity. 2016a;24:2593-2599. |
R834798C003 (Final) |
not available |
Journal Article | Li W, Wilker EH, Dorans K, Rice MB, Schwartz J, Coull B, Koutrakis P, Gold DR, Keaney JFJ, Lin H, Vasan R, Benjamin EJ, Mittleman MA. Short-Term Exposure to Air Pollution and Biomarkers of Oxidative Stress:The Framingham Heart Study. JournAL Of the American Heart Association 2016; DOI:10.1161/JAHA.115.002742:1-8. |
R834798 (2016) R834798C003 (Final) |
not available |
Journal Article | Ljungman PL, Wilker EH, Rice MB, Austin E, Schwartz J, Gold DR, Koutrakis P, Benjamin EJ, Vita JA, Mitchell GF, Vasan RS, Hamburg NM, Mittleman MA. The Impact of Multipollutant Clusters on the Association Between Fine Particulate Air Pollution and Microvascular Function. Epidemiology 2016; 27:194-201. |
R834798 (2016) R834798C003 (Final) |
not available |
Presentation | Doran KS, Ljungman P, Schwartz J, Coull B, Buring JE, D'Agostino R, Massaro J, Hoffmann U, O'Donnell C, Mittleman MA. Association of traffic-related air pollution and coronary artery calcium in the Framingham Heart Study. Presented at the 48th Annual Meeting of the Society for Epidemiologic Research, Denver, CO, June 16-19, 2015. |
R834798 (2015) R834798 (Final) R834798C003 (Final) |
not available |
Presentation | Li W, Wilker EH, Dorans KS, Rice MB, Schwartz J, Coull B, Koutrakis P, Vasan RS, Benjamin EJ, Mittleman MA. Short-term exposure to air pollution and biomarkers of oxidative stress: the Framingham Heart Study. Presented at the 48th Annual Meeting of the Society for Epidemiologic Research, Denver, CO, June 16-19, 2015. |
R834798 (2015) R834798 (Final) R834798C003 (Final) |
not available |
Presentation | Ljungman PL. Short-term exposure to air pollution and arterial stiffness in the Framingham Heart Study. Presented at the 26th Annual Conference of the International Society of Environmental Epidemiology, Seattle, WA, August 24-28, 2014. |
R834798 (Final) R834798C003 (2014) R834798C003 (Final) |
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Presentation | Ljungman PL, Wilker EH, Rice MB, Austin E, Schwartz J, Gold DR, Koutrakis P, Vita JA, Mitchell GF, Vasan RS, Benjamin EJ, Mittleman MA, Hamburg NM. Multi-pollutant mixtures and digital vascular function in the Framingham Heart Study. Poster presented at the American Heart Association 2014 Scientific Sessions:Cardiovascular Disease, Epidemiology and Prevention--Nutrition, Physical Activity and Metabolism, San Francisco, CA, March 18-21, 2014 (Abstract P247). |
R834798 (Final) R834798C003 (2014) |
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Presentation | Lue S-H, Wellenius GA, Wilker EH, Mittleman MA. Chronic exposure to traffic pollution is associated with reduced glomerular filtration rate. Presented at the 23rd Annual Conference of the International Society for Environmental Epidemiology, Barcelona, Spain, September 13-16, 2011 (Abstract O-0001). |
R834798 (2010) R834798 (2011) R834798 (2014) R834798 (Final) R834798C003 (2010) R834798C003 (2011) R834798C003 (2014) R834798C003 (Final) |
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Presentation | Rice MB. Residential exposure to air pollution and lung function in the Framingham Heart Study. Presented at the 26th Annual Conference of the International Society of Environmental Epidemiology, Seattle, WA, August 24-28, 2014. |
R834798 (Final) R834798C003 (2014) R834798C003 (Final) |
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Presentation | Rosenbloom JI, Wilker EH, Mitchell GF, Coull BA, Schwartz J, Hamburg NA, Benjamin EJ, Gold DR, Ramachandran VS, Vita JA, Koutrakis P, Mittleman MA, Levy DE. Short-term exposure to ambient air pollution and blood pressure in the Framingham Heart Study. Presented at the 23rd Annual Conference of the International Society of Environmental Epidemiology, Barcelona, Spain, September 13-16, 2011 (Abstract P-0031). |
R834798 (2010) R834798 (2011) R834798 (2014) R834798C003 (2010) R834798C003 (2011) R834798C003 (2014) R834798C003 (Final) |
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Presentation | Wilker EH, Schwartz J, Gold DR, Koutrakis P, Coull BA, Vita JA, Benjamin EJ, Mittleman MA, Hamburg NM. Exposure to ambient air pollution and flow mediated dilation: susceptibility of individuals with diabetes in the Framingham Offspring Study. Presented at the American Heart Association Council on Cardiovascular Disease Epidemiology and Prevention Scientific Sessions 2011, Atlanta, GA, March 23-25, 2011 (Abstract MP68). |
R834798 (2010) R834798 (2011) R834798 (2014) R834798 (Final) R834798C003 (2010) R834798C003 (2011) R834798C003 (2014) R834798C003 (Final) |
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Presentation | Wilker EH. Green space and mortality following ischemic stroke. Presented at the American Heart Association 2014 Scientific Sessions:Cardiovascular Disease, Epidemiology and Prevention--Nutrition, Physical Activity and Metabolism, San Francisco, CA, March 18-21, 2014. |
R834798 (Final) R834798C003 (2014) R834798C003 (Final) |
not available |
Presentation | Wilker EH. Long-term exposure to particulate matter and proximity to roads and measures of brain structure. Presented at the 26th Annual Conference of the International Society of Environmental Epidemiology, Seattle, WA, August 24-28, 2014. |
R834798 (Final) R834798C003 (2014) R834798C003 (Final) |
not available |
Presentation | Rice MB, Dorans KS, Li W, Wilker EH, Ljungman PL, Gold DR, Koutrakis P, O'Connor GT, Mittleman MA, Washko GR. Exposure to Traffic and Fine Particulate Matter and CT Measures of Lung Volume, Mass, Density, and Airway Size in the Framingham Heart Study. International Society for Environmental Epidemiology (ISEE), Rome, Italy. September 2016. |
R834798C003 (Final) |
not available |
Presentation | Dorans KS, Li W, Wilker EH, O’Donnell CJ, Schwartz J, Coull BA, Mittleman MA. Applying quantile regression in the setting of zero-inflated or skewed data. Society for Epidemiologic Research, Seattle, WA. June 2017. |
R834798C003 (Final) |
not available |
Presentation | Mittleman MA. Exposure to Traffic and Fine Particulate Matter and Aortic Calcium in the Framingham Offspring and Third Generation Cohorts. AHA EPI/Lifestyle 2016 Scientific Sessions. Phoenix, AZ. March 2016. |
R834798C003 (Final) |
not available |
Presentation | Li W, Wilker EH, Dorans KS, Rice MB, Ljungman PL, Schwartz J, Coull BA, Koutrakis P, Gold DR, Vasan RS, Benjamin EJ, Mittleman MA. Short-term exposure to ambient air pollution and circulating biomarkers of systemic inflammation: the Framingham Heart Study. Presented at EPI/Lifestyle 2017 Scientific Sessions, Portland, OR, March 7-10, 2017. |
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Presentation | Rice MB, Li W, Wilker EH, Gold DR, Schwartz J, Koutrakis P, Washko GR, O’Connor GT, Mittleman MA. Extreme Temperatures and Lung Function in the Framingham Heart Study. American Thoracic Society. Washington, DC. May 2017. |
R834798C003 (Final) |
not available |
Presentation | Rice MB, Ljungman PL, Wilker EH, Dorans KS, Kloog I, Gold DR, Schwartz J, Koutrakis P, Washko GR, O'Connor GT, Mittleman MA. Long-Term Air Pollution Exposure and Longitudinal Change in Lung Function and the Diffusion Capacity of Carbon Monoxide in the Framingham Heart Study. Presented at the American Thoracic Society Annual Meeting, Denver, CO. May 2015. Am J Respir Crit Care Med 191;2015:A5237. |
R834798C003 (Final) |
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Presentation | Dorans KS, Wilker EH, Li W, Rice MB, Ljungman PL, Schwartz J, Coull BA, Buring JE, Kloog I, Koutrakis P, D’Agostino RB, Massaro JM, Hoffmann U, O’Donnell CJ,. |
R834798C003 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.