Grantee Research Project Results
Publications Details for Grant Number R832414C005
Project 5 -- Architecture Development and Particle Deposition
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Journal Article | Bein KJ, Zhao Y, Wexler AS. Conditional sampling for source-oriented toxicological studies using a single particle mass spectrometer. Environmental Science & Technology 2009;43(24):9445-9452. |
R832414 (Final) R832414C005 (Final) |
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| Journal Article | Lee DY, Wexler AS, Fanucchi MV, Plopper CG. Expiration rate drives human airway design. Journal of Theoretical Biology 2008;253(2):381-387. |
R832414 (2009) R832414C005 (2008) R832414C005 (Final) |
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| Journal Article | Lee DY, Wallis C, Wexler AS, Schelegle ES, Van Winkle LS, Plopper CG, Fanucchi MV, Kumfer B, Kennedy IM, Chan JKW. Small particles disrupt postnatal airway development. Journal of Applied Physiology 2010;109(4):1115-1124. |
R832414 (Final) R832414C001 (2010) R832414C005 (2010) R832414C005 (Final) |
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| Journal Article | Lee DY, Wallis CD, Van Winkle LS, Wexler AS. Disruption of tracheobronchial airway growth following postnatal exposure to ozone and ultrafine particles. Inhalation Toxicology 2011;23(9):520-531. |
R832414 (Final) R832414C005 (Final) |
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| Journal Article | Lee DY, Wexler AS. Simulated annealing implementation with shorter Markov chain length to reduce computational burden and its application to the analysis of pulmonary airway architecture. Computers in Biology and Medicine 2011;41(8):707-715. |
R832414 (Final) R832414C005 (Final) |
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| Journal Article | Lee DY, Willits N, Wexler AS. Detecting alterations in pulmonary airway development with airway-by-airway comparison. Annals of Biomedical Engineering 2011;39(6):1805-1814. |
R832414 (Final) R832414C005 (Final) |
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| Journal Article | Lee DY, Srirama PK, Wallis C, Wexler AS. Postnatal growth of tracheobronchial airways of Sprague-Dawley rats. Journal of Anatomy 2011;218(6):717-725. |
R832414 (Final) R832414C005 (Final) |
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| Journal Article | Lee DY, Wexler AS. Particle deposition in juvenile rat lungs: a model study. Journal of Aerosol Science 2011;42(9):567-579. |
R832414 (Final) R832414C005 (Final) |
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| Journal Article | Lee D, Park SS, Ban-Weiss GA, Fanucchi MV, Plopper CG, Wexler AS. Bifurcation model for characterization of pulmonary architecture. Anatomical Record 2008;291(4):379-389. |
R832414 (2009) R832414C005 (2007) R832414C005 (2008) R832414C005 (Final) |
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| Journal Article | Lee D, Fanucchi MV, Plopper CG, Fung J, Wexler AS. Pulmonary architecture in the conducting regions of six rats. Anatomical Record 2008;291(8):916-926. |
R832414 (2009) R832414C005 (2008) R832414C005 (Final) |
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| Journal Article | Srirama PK, Wallis CD, Lee DY, Wexler AS. Imaging extra-thoracic airways and deposited particles in laboratory animals. Journal of Aerosol Science 2012;45:40-49. |
R832414 (Final) R832414C005 (Final) |
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| Journal Article | Tebockhorst S, Lee D, Wexler AS, Oldham MJ. Interaction of epithelium with mesenchyme affects global features of lung architecture: a computer model of development. Journal of Applied Physiology 2007;102(1):294-305. |
R832414 (2009) R832414C005 (2007) R832414C005 (2008) R832414C005 (Final) |
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| Journal Article | Wexler AS, Johnston MV. What have we learned from highly time-resolved measurements during EPA's Supersites Program and related studies? Journal of the Air & Waste Management Association 2008;58(2):303-319. |
R832414 (Final) R832414C005 (Final) |
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| Presentation | Lee DY, Wexler AS, Plopper C, Yang K, Miller DF, Boone JM. Characterization of lung airway architecture using a flexible bifurcation model and simulated annealing. Presented at the International Conference of the American Thoracic Society, San Diego, CA, May 19-24, 2006. |
R832414C005 (2006) R832414C005 (Final) |
not available |
| Presentation | Lee D, Schelegle E, Wallis C, Fanucchi MV, Van Winkle L, Plopper CG, Wexler AS. Effects of post-natal ozone or particle exposure on the structural and functional differences in rat lungs. Presented at the International Conference of the American Thoracic Society, San Diego, CA, May 15-20, 2009. |
R832414C005 (2009) R832414C005 (Final) |
not available |
| Presentation | Lee D, Schelegle E, Wallis C, Fanucchi MV, Van Winkle L, Plopper CG, Wexler AS. Structural and functional differences in rat lungs due to post-natal ozone or particle exposure. Presented at the Society of Toxicology 48th Annual Meeting & ToxExpo, Baltimore, MD, March 15-19, 2009. |
R832414C005 (2009) R832414C005 (Final) |
not available |
| Presentation | Lee D, Schelegle E, Wallis C, Fanucchi MV, Van Winkle L, Plopper CG, Wexler AS. Structural and functional changes in rat lungs due to post-natal exposure to ozone with and without particles. Presented at the 2010 American Association for Aerosol Research (AAAR) Air Pollution and Health Specialty Conference, Bridging the Gap From Sources to Health Outcomes, San Diego, CA, March 22-26, 2010. |
R832414 (2010) R832414 (Final) R832414C001 (2010) R832414C001 (Final) R832414C005 (2010) R832414C005 (Final) |
not available |
| Presentation | Lee D, Srirama PK, Wallis CD, Wexler AS. Airway-by-airway identification of aerosol deposition in the laboratory animal lung. Presented at the American Association for Aerosol Research (AAAR) 30th Annual Conference, Orlando, FL, October 3-7, 2011. |
R832414C005 (Final) |
not available |
| Presentation | Lee D, Wallis C, Wexler AS. Detecting disruption in airway development due to PM exposure by comparing pulmonary airway trees. Presented at the International Conference of the American Thoracic Society, Denver, CO, May 13-18, 2011. |
R832414C005 (Final) |
not available |
| Presentation | Lee D, Wexler AS, Fanucchi MV, Plopper CG. Optimal structure of human airway architecture. Presented at the Biomedical Engineering Society Annual Fall Meeting, Los Angeles, CA, September 26-29, 2007. |
R832414C005 (Final) |
not available |
| Presentation | Srirama PK, Wallis CD, Lee D, Wexler AS. Imaging particle and drug deposition in airways of laboratory animals. Poster presented at Respiratory Drug Delivery (RDD) Europe, Berlin, Germany, May 3-6, 2011. |
R832414C005 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.