IRIS

Ethylbenzene

CASRN 100-41-4

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (21 pp, 148 K) last updated: 01/31/1987

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Hepatic, Urinary 1 x 10-1 Liver and kidney toxicity NOEL : 9.71 x 101
mg/kg-day
1000 Low

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (21 pp, 148 K) last updated: 03/01/1991

System RfC (mg/m3) Basis PoD Composite UF Confidence
Developmental 1 Developmental toxicity NOAEL (HEC): 4.34 x 102
mg/m3
300 Low

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (21 pp, 148 K) last updated: 09/17/1988

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Nonclassifiable due to lack of animal bioassays and human studies.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (21 pp, 148 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (21 pp, 148 K)

Not assessed under the IRIS Program.


Note: The ethylbenzene (re)assessment was suspended in Dec 2018, but may be restarted as Agency priorities change.

Assessment Manager(s): James Avery (avery.james@epa.gov)

Step Assessment Materials Released to the Public Release Date Public Meeting Date
1 Problem Formulation Materials 09/2017 TBD
  Suspended 12/2018  

You will need Adobe Reader to view some of the files on this page. See EPA’s PDF page to learn more.