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Records 1 to 25 of 28 records from [ORD-NHEERL] published between 11/20/2012 and 11/20/2017 from author Chris Corton

2017
Kumar, R., L. Mota, E. Litoff, J. Rooney, T. Boswell, E. Courter, C. Henderson, J. Hernandez, C. Corton, D. Moore, AND W. Baldwin. Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice. PLOS ONE . Public Library of Science, San Francisco, CA, 12(3):e174355, (2017).
Mesnage, R., A. Phedonos, M. Biserni, M. Arno, S. Balu, C. Corton, R. Ugarte, AND M. Antoniou. Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 108:30-42, (2017).
Mesnage, R., A. Phedonos, M. Arno, S. Balu, C. Corton, R. Ugarte, AND M. Antoniou. Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide ingredients. SOT, Baltimore, Maryland, March 13 - 16, 2017.
Rooney, J., N. Ryan, B. Chorley, S. Hester, E. Kenyon, Judy Schmid, BJ George, M. Hughes, Y. Sey, A. Tennant, D. MacMillan, J. Simmons, C. McQueen, A. Pandiri, C. Wood, AND C. Corton. Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 160(1):15–29, (2017).
Rooney, J., N. Ryan, R. Houtman, R. van Beuningen, J. Hsieh, S. Chen, AND C. Corton. Identification of Novel Chemical Modulators of the Estrogen Receptor α (ERα) in a Gene Expression Compendium. Society of Toxicology, Baltimore, Maryland, March 13 - 16, 2017.
Corton, C. AND J. Rooney. Integrating toxicogenomics data into cancer adverse outcome pathways. Society of Toxicology, Baltimore, Maryland, March 13 - 16, 2017.
Corton, C. Leveraging toxicogenomics data to build predictive biomarkers supporting AOP assessment. HESI Genomics Meeting, Montreal, Canada, CANADA, May 25 - 26, 2017.
Rooney, J., S. Hiemstra, B. Chorley, B. van de Water, AND C. Corton. Mining a human transcriptome database for chemical modulators of Nrf2. World Congress on alternatives and animal use in the life sciences, Seattle, Washington, August 20 - 24, 2017.
Das, K., C. Wood, M. Lin, A. Starkov, C. Lau, K. Wallace, C. Corton, AND B. Abbott. Perfluoroalky acids-induced liver steatosis: Effects on genes controlling lipid homeostasis. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 378:32-52, (2017).
Mesnage, R., A. Phedonos, M. Arno, S. Balu, C. Corton, AND M. Antoniou. Transcriptome profiling reveals bisphenol A alternatives activate estrogen receptor alpha in human breast cancer cells. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 158(2):431-443, (2017).
2016
Vanduyn, N., B. Chorley, R. Tice, R. Judson, AND C. Corton. A gene expression biomarker accurately predicts estrogen receptor α modulation in a human gene expression compendium. SOT, New Orleans, LA, March 13 - 17, 2016.
Oshida, K., D. Waxman, AND C. Corton. Chemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver Transcriptome. PLOS ONE . Public Library of Science, San Francisco, CA, 11(3):NA, (2016).
Oshida, K., N. Vasani, D. Waxman, AND C. Corton. Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event. PLOS ONE . Public Library of Science, San Francisco, CA, 11(3):NA, (2016).
Lake, A., C. Wood, V. Bhat, B. Chorley, G. Carswell, Y. Sey, E. Kenyon, B. Padnos, T. Moore, A. Tennant, Judy Schmid, BJ George, D. Ross, M. Hughes, C. Corton, J. Simmons, C. McQueen, AND S. Hester. Dose and Effect Thresholds for Early Key Events in a Mode of PPARa-Mediated Action. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 149(2):312-325, (2016).
Rooney, J. AND C. Corton. Mining a human transcriptome database for Nrf2 modulators. SOT, New Orleans, LA, March 13 - 17, 2016.
Vanduyn, N., B. Chorley, R. Tice, R. Judson, AND C. Corton. Moving Toward Integrating Gene Expression Profiling into High-throughput Testing:A Gene Expression Biomarker Accurately Predicts Estrogen Receptor α Modulation in a Microarray Compendium. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 151(1):88-103, (2016).
2015
Oshida, K., N. Vasani, W. Ward, R. Thomas, D. Applegate, Mitch Rosen, B. Abbott, C. Lau, G. Guo, L. Aleksunes, C. Klaassen, AND C. Corton. Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium. PLOS ONE . Public Library of Science, San Francisco, CA, 10(2):e0112655, (2015).
Oshida, K., N. Vasani, W. Ward, R. Thomas, D. Applegate, F. Gonzalez, L. Aleksunes, C. Klaassen, AND C. Corton. Screening a mouse liver gene expression Compendium Identifies Effectors of the Aryl Hydrocarbon receptor (AhR). TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 336:99-112, (2015).
Gandhy, S., P. Imanirad, U. Jin, V. Nair, E. Hedrick, Y. Cheng, C. Corton, K. Kim, AND S. Safe. Specificity Protein (Sp) Transcription Factors and Metformin Regulate Expression of the Long Non-coding RNA HULC. ONCOGENE. MacMillan Magazines LIMITED, London, Uk, 6(28):26359-26372, (2015).
Cheng, Y., I. Jutooru, G. Chadalapaka, C. Corton, AND S. Safe. The Long Non-coding RNA HOTTIP Enhances Pancreatic Cancer Cell Proliferation, Survival and Migration. Oncotarget. Impact Journals, LLC, Orchard Park, NY, 6(13):10840-10852, (2015).
2014
VanDyun, N., J. Franzosa, K. Houck, W. Ward, B. Chorley, AND C. Corton. Building gene expression signatures indicative of transcription factor activation to predict AOP modulation. Presented at GEMS, RTP, NC, October 22, 2014.
VanDuyn, N., J. Franzosa, K. Houck, W. Ward, B. Chorley, AND C. Corton. Building predictive gene signatures through simultaneous assessment of transcription factor activation and gene expression. Presented at ToxCast Data Summit, RTP, NC, September 29 - 30, 2014.
Wood, C., M. Jokinen, C. Johnson, G. Olson, S. Hester, M. George, B. Chorley, G. Carswell, J. Carter, C. Wood, V. Bhat, C. Corton, AND A. Deangelo. Comparative Time Course Profiles of Phthalate Stereoisomers in Mice. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 139(1):21-34, (2014).
Corton, C., M. Cunningham, B. Hummer, C. Lau, B. Meek, J. Peters, J. Popp, L. Rhomberg, J. Seed, AND J. Klaunig. Mode of action framework analysis for receptor-mediated toxicity: the Peroxisome Proliferator-Activated Receptor alpha (PPARα) as a case study. CRITICAL REVIEWS IN TOXICOLOGY. CRC Press LLC, Boca Raton, FL, 44(1):1-49, (2014).