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Records 1 to 25 of 122 records from [ORD-NHEERL] from author Chris Corton

2021
Cho, E., A. Rowan-Carroll, A. Williams, C. Corton, H. Li, A. Fornace, C. Hobbs, AND C. Yauk. Development and Validation of the TGx-HDACi Transcriptomic Biomarker to Detect Histone Deacetylase Inhibitors in Human TK6 Cells. Archives of Toxicology. Springer, New York, NY, 95(5):1631-1645, (2021). https://doi.org/10.1007/s00204-021-03014-2
2020
Corton, Jon, T. Hill, J. Sutherland, J. Stevens, AND J. Rooney. A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-Term Assays. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 177(1):11-26, (2020). https://doi.org/10.1093/toxsci/kfaa101
Li, H., S. Zhang, W. Zhang, S. Chen, A. Rabearivony, Y. Shi, J. Liu, Jon Corton, AND C. Liu. Endogenous circadian time genes expressions in the liver of mice under constant darkness. BMC Genomics. BioMed Central Ltd, London, Uk, 21:224, (2020). https://doi.org/10.1186/s12864-020-6639-4
Hill, T., J. Rooney, J. Abedini, H. El-Masri, C. Wood, AND Jon Corton. Gene Expression Thresholds Derived From Short-term Exposures Identify Rat Liver Tumorigens. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 177(1):41-59, (2020). https://doi.org/10.1093/toxsci/kfaa102
Jackson, A., J. Liu, B. Vallanat, C. Jones, M. Nelms, G. Patlewicz, AND Jon Corton. Identification of Novel Activators of the Metal Responsive Transcription Factor (MTF-1) Using a Gene Expression Biomarker in a Microarray Compendium. Metallomics. Royal Society of Chemistry, London, Uk, 12(9):1400-1415, (2020). https://doi.org/10.1039/d0mt00071j
Rooney, J., B. Chorley, S. Hiemstra, S. Wink, X. Wang, D. Bell, B. van de Water, AND Jon Corton. Mining a human transcriptome database for chemical modulators of Nrf2 (PLOS ONE). PLOS ONE . Public Library of Science, San Francisco, CA, 15(9):e0239367, (2020). https://doi.org/10.1371/journal.pone.0239367
Corton, Jon, K. Korunes, J. Abedini, H. El-Masri, J. Brown, K. Friedman, Y. Liu, C. Martini, S. He, AND J. Rooney. Thresholds Derived from Common Measures in Rat Studies are Predictive of Liver Tumorigenic Chemicals. TOXICOLOGIC PATHOLOGY. Society of Toxicology, RESTON, VA, 48(7):857-874, (2020). https://doi.org/10.1177/0192623320960412
Liu, J., J. Cui, S. Gunewardena, C. Klaasseen, B. Chorley, AND Jon Corton. Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 435:152409, (2020). https://doi.org/10.1016/j.tox.2020.152409
2019
Rooney, J., B. Chorley, AND C. Corton. A gene expression biomarker identifies factors that modulate sterol regulatory element binding protein. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 10:63-77, (2019). https://doi.org/10.1016/j.comtox.2018.12.007
Cho, E., J. Buick, A. Williams, R. Chen, H. Li, C. Corton, A. Fornace, J. Aubrecht, AND C. Yauk. Assessment of the performance of the TGx-DDI biomarker to detect DNA damage-inducing agents using quantitative RT- PCR in TK6 cells. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. John Wiley & Sons, Inc, Hoboken, NJ, 60(2):122-133, (2019). https://doi.org/10.1002/em.22257
Wen, X., A. Baker, C. Klaassen, C. Corton, J. Richardson, AND L. Aleksunes. Hepatic carboxylesterases are differentially regulated in PPARα-null mice treated with perfluorooctanoic acid. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 416:15-22, (2019). https://doi.org/10.1016/j.tox.2019.01.014
Corton, Jon, K. Witt, AND C. Yauk. Identification of p53 Activators in a Human Microarray Compendium. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 32(9):1748-1759, (2019). https://doi.org/10.1021/acs.chemrestox.9b00052
2018
Rooney, J., K. Oshida, N. Vasani, B. Vallanat, N. Ryan, B. Chorley, X. Wang, D. Bell, K. Wu, L. Aleksunes, C. Klaassen, T. Kensler, AND C. Corton. Activation of Nrf2 in the Liver is Associated with Suppression of the Growth Hormone-Regulated STAT5b Transcription Factor. PLOS ONE . Public Library of Science, San Francisco, CA, 13(8):1-30, (2018). https://doi.org/10.1371/journal.pone.0200004
Rooney, J., T. Hill, C. Qin, F. Sistare, AND C. Corton. Adverse outcome pathway-driven identification of rat liver tumorigens in short-term assays. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 356:99-113, (2018). https://doi.org/10.1016/j.taap.2018.07.023
Cho, E., J. Buick, A. Williams, R. Chen, H. Li, C. Corton, A. Fornace, J. Aubrecht, AND C. Yauk. Application of the TGx-DDI Biomarker to Identify DNA Damage-Inducing Agents using Real-Time Quantitative PCR arrays. EMGS, san antonio, Texas, September 22 - 26, 2018.
Rooney, J., K. Oshida, R. Kumar, W. Baldwin, AND C. Corton. Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(1):172-189, (2019). https://doi.org/10.1093/toxsci/kfy231
Rooney, J., B. Chorley, N. Kleinstreuer, AND C. Corton. Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 166(1):146-162, (2018). https://doi.org/10.1093/toxsci/kfy187
Corton, C., J. Peters, AND J. Klaunig. The PPARα-dependent rodent liver tumor response is not relevant to humans: Addressing misconceptions. Archives of Toxicology. Springer, New York, NY, 92(1):83-119, (2017).