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See all EPA publications for Chris Corton Include records from any date Include records from any EPA source

Records 1 to 25 of 32 records from [ORD-NHEERL] published between 05/22/2013 and 05/22/2018 from author Chris Corton

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2018

Corton, C. Identification of Potential Chemical Carcinogens in Compendia of Gene Expression Profiles. sot, san antonio, Tx, March 12 - 15, 2018.

Corton, C. Identification of potential chemical carcinogens in compendia of gene expression profiles. SOT, San Antonio, Texas, March 12 - 15, 2018.

Corton, C., J. Peters, AND J. Klaunig. The PPARα-dependent rodent liver tumor response is not relevant to humans: Addressing misconceptions. Archives of Toxicology. Springer, New York, NY, 92(1):83-119, (2017).

Corton, C., N. Kleinstreuer, AND J. Rooney. Using Gene Expression Biomarkers to Identify Chemicals that Induce Key Events in Cancer and Endocrine Disruption AOPs: Androgen Receptor as an Example. SETAC, Durham, NC, April 17 - 19, 2018.

Corton, C., N. Kleinstreuer, AND J. Rooney. Using Gene Expression Biomarkers to Identify Chemicals that Induce Key Events in Cancer and Endocrine Disruption Adverse Outcome Pathways: Androgen Receptor as an Example. SETAC, DURHAM, NC, April 16 - 18, 2018.

Corton, C. Using gene expression biomarkers to prioritize chemicals in high throughput transcriptomic screening programs. Invited speaker Bayer, Durham, NC, March 20, 2018.

2017

Hill, T., C. Corton, AND C. Wood. AOP-driven Predictive Models for Carcinogenicity: an exercise in interoperable data application. OpenTox Euro 2017, Basel, Switzerland, SWITZERLAND, November 21 - 23, 2017.

Kumar, R., L. Mota, E. Litoff, J. Rooney, T. Boswell, E. Courter, C. Henderson, J. Hernandez, C. Corton, D. Moore, AND W. Baldwin. Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice. PLOS ONE . Public Library of Science, San Francisco, CA, 12(3):e174355, (2017).

Mesnage, R., A. Phedonos, M. Biserni, M. Arno, S. Balu, C. Corton, R. Ugarte, AND M. Antoniou. Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 108:30-42, (2017).

Mesnage, R., A. Phedonos, M. Arno, S. Balu, C. Corton, R. Ugarte, AND M. Antoniou. Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide ingredients. SOT, Baltimore, Maryland, March 13 - 16, 2017.

Rooney, J., N. Ryan, B. Chorley, S. Hester, E. Kenyon, Judy Schmid, BJ George, M. Hughes, Y. Sey, A. Tennant, D. MacMillan, J. Simmons, C. McQueen, A. Pandiri, C. Wood, AND C. Corton. Genomic effects of androstenedione and sex-specific liver cancer susceptibility in mice. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 160(1):15–29, (2017).

Rooney, J., N. Ryan, R. Houtman, R. van Beuningen, J. Hsieh, S. Chen, AND C. Corton. Identification of Novel Chemical Modulators of the Estrogen Receptor α (ERα) in a Gene Expression Compendium. Society of Toxicology, Baltimore, Maryland, March 13 - 16, 2017.

Corton, C. AND J. Rooney. Integrating toxicogenomics data into cancer adverse outcome pathways. Society of Toxicology, Baltimore, Maryland, March 13 - 16, 2017.

Corton, C. Leveraging toxicogenomics data to build predictive biomarkers supporting AOP assessment. HESI Genomics Meeting, Montreal, Canada, CANADA, May 25 - 26, 2017.

Rooney, J., S. Hiemstra, B. Chorley, B. van de Water, AND C. Corton. Mining a human transcriptome database for chemical modulators of Nrf2. World Congress on alternatives and animal use in the life sciences, Seattle, Washington, August 20 - 24, 2017.

Das, K., C. Wood, M. Lin, A. Starkov, C. Lau, K. Wallace, C. Corton, AND B. Abbott. Perfluoroalky acids-induced liver steatosis: Effects on genes controlling lipid homeostasis. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 378:32-52, (2017).

Mesnage, R., A. Phedonos, M. Arno, S. Balu, C. Corton, AND M. Antoniou. Transcriptome profiling reveals bisphenol A alternatives activate estrogen receptor alpha in human breast cancer cells. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 158(2):431-443, (2017).

2016

Corton, C. A biomarker-based screen of a gene expression compendium reveals regulation of Nrf2 by CAR and STAT5b. SOT 2016, New Orleans, LA, March 13 - 17, 2016.

Vanduyn, N., B. Chorley, R. Tice, R. Judson, AND C. Corton. A gene expression biomarker accurately predicts estrogen receptor α modulation in a human gene expression compendium. SOT, New Orleans, LA, March 13 - 17, 2016.

Oshida, K., D. Waxman, AND C. Corton. Chemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver Transcriptome. PLOS ONE . Public Library of Science, San Francisco, CA, 11(3):NA, (2016).

Oshida, K., N. Vasani, D. Waxman, AND C. Corton. Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event. PLOS ONE . Public Library of Science, San Francisco, CA, 11(3):NA, (2016).

Lake, A., C. Wood, V. Bhat, B. Chorley, G. Carswell, Y. Sey, E. Kenyon, B. Padnos, T. Moore, A. Tennant, Judy Schmid, BJ George, D. Ross, M. Hughes, C. Corton, J. Simmons, C. McQueen, AND S. Hester. Dose and Effect Thresholds for Early Key Events in a Mode of PPARa-Mediated Action. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 149(2):312-325, (2016).

Rooney, J. AND C. Corton. Mining a human transcriptome database for Nrf2 modulators. SOT, New Orleans, LA, March 13 - 17, 2016.

Vanduyn, N., B. Chorley, R. Tice, R. Judson, AND C. Corton. Moving Toward Integrating Gene Expression Profiling into High-throughput Testing:A Gene Expression Biomarker Accurately Predicts Estrogen Receptor α Modulation in a Microarray Compendium. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 151(1):88-103, (2016).

2015

Oshida, K., N. Vasani, W. Ward, R. Thomas, D. Applegate, Mitch Rosen, B. Abbott, C. Lau, G. Guo, L. Aleksunes, C. Klaassen, AND C. Corton. Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium. PLOS ONE . Public Library of Science, San Francisco, CA, 10(2):e0112655, (2015).