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See all EPA publications for Thomas Knudsen Include records from any EPA source

Records 1 to 25 of 294 records from [ORD-NCCT] from author Thomas Knudsen

2021

Baker, N. AND T. Knudsen. Literature Mining Tool for Detailed Review Paper on the Retinoid System. In Proceedings, OECD Retinoid Project workshop, Brussels, BELGIUM, February 14 - 15, 2017. OECD Press, Paris, France, 1-240, (2021). https://doi.org/10.23645/epacomptox.5588635

2020

Saili, K., T. Antonijevic, T. Zurlinden, I. Shah, C. Deisenroth, AND T. Knudsen. Molecular characterization of a toxicological tipping point during human stem cell differentiation. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 91(January 2020):1-13, (2020). https://doi.org/10.1016/j.reprotox.2019.10.001

Zurlinden, T., N. Kleinstreuer, A. Lumen, M. Xia, N. Baker, AND T. Knudsen. Predicting Developmental Toxicity Potential using Pluripotent Embryonic Stem Cell Assays and the ToxCast Library (SOT 2020). Society of Toxicology (SOT) 2020 Annual Meeting, Anaheim, California, March 15 - 19, 2020.

Zurlinden, T., K. Saili, N. Rush, P. Kothiya, R. Judson, K. Houck, E. Hunter, N. Baker, J. Palmer, R. Thomas, AND T. Knudsen. Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 174(2):189-209, (2020). https://doi.org/10.1093/toxsci/kfaa014

2019

Piersma, A., N. Baker, L. Burgoon, G. Daston, T. Knudsen, AND Y. Staal. An AOP-based Ontology for Spina Bifida Caused by Disturbance in Retinoic Acid Signaling. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019.

Staal, Y., N. Baker, J. Pennings, G. Daston, T. Knudsen, AND A. Piersma. 20190908 - Towards a Mechanistic Approach in Toxicology: Retinoic Acid Balance Disturbance Leading to Neural Tube Closure Defects - EuroTox 2019. European Societies of Toxicology (EUROTOX) annual conference, Helsinki, N/A, FINLAND, September 08 - 11, 2019.

Knudsen, T. 20190917 - Status and Prospect of the Virtual Embryo Program (ETS). European Teratology Society 47th annual meeting, Cologne, N/A, GERMANY, September 17 - 20, 2019. https://doi.org/10.23645/epacomptox.9922475

Baker, N. AND T. Knudsen. Abstract Sifter: A literature informatics tool for computational toxicology (ASCCT). ASCCT Annual Meeting, Gaithersburg, MD, September 25 - 26, 2019.

Knudsen, T. Application of AOPs to Developmental Outcomes. Teratology Society's 59th Annual Meeting, San Diego, CA, June 22 - 26, 2019. https://doi.org/10.23645/epacomptox.8179184

Zurlinden, T., K. Saili, S. Hunter, N. Baker, AND T. Knudsen. Characterizing Developmental Toxicity Through Pluripotent Embryonic Stem Cell Assays and the ToxCast Library. Presented at SOT Annual Meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7844885

Baker, N., N. Sipes, J. Franzosa, D. Belair, B. Abbott, R. Judson, AND T. Knudsen. Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature. Birth Defects Research. John Wiley & Sons, Inc., Hoboken, NJ, , 1-21, (2019). https://doi.org/10.1002/bdr2.1581

Knudsen, T. Computational Approaches to Developmental and Reproductive Toxicology. Presented at UNC Advanced Toxicology course: reproductive toxicology section, Chapel Hill, NC, April 24, 2019. https://doi.org/10.23645/epacomptox.8038712

Knudsen, T. Computational systems biology: translational tools for data integration and modeling. Presented at International Congress of Toxicology (ICT) triennial conference, Honolulu, Hawaii, July 15 - 18, 2019. https://doi.org/10.23645/epacomptox.8983775

Knudsen, T. Data Management, Publication/Authorship, and Peer Review. Presented at Teratology Society's 59th Annual Meeting, San Diego, CA, June 22 - 26, 2019. https://doi.org/10.23645/epacomptox.8860466

Saili, K., T. Zurlinden, T. Antonijevic, I. Shah, C. Deisenroth, AND T. Knudsen. Endodermal Differentiation Trajectories Diverge with Increasing All-Trans Retinoic Acid Exposure. Presented at Society of Toxicology, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7845026

Knudsen, T. Future of Reproductive and Developmental Toxicity Testing: computational and organoids. Presented at Practical Reproductive and Developmental Toxicology course, Gaithersburg, MD, May 13 - 17, 2019. https://doi.org/10.23645/epacomptox.8104838

Wei, Z., S. Sakamuru, L. Zhang, J. Zhao, R. Huang, N. Kleinstreuer, Y. Chen, Y. Shu, T. Knudsen, AND M. Xia. Identification and profiling of environmental chemicals that inhibit the TGFβ/SMAD signaling pathway. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 32(12):2433-2444, (2019). https://doi.org/10.1021/acs.chemrestox.9b00228

Baker, N., A. Williams, AND T. Knudsen. Literature-based cheminformatics for research in chemical toxicity (ACS Spring 2019). Presented at ACS National Spring Meeting, Orlando, FL, March 31 - April 04, 2019. https://doi.org/10.23645/epacomptox.7971533

Knudsen, T. Mining and Modeling ToxCast/Tox21 data for developmental toxicity. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7836980

Saili, K., J. Franzosa, N. Baker, R. Ellis-Hutchings, R. Settivari, E. Carney, R. Spencer, T. Zurlinden, N. Kleinstreuer, S. Li, M. Xia, AND T. Knudsen. Systems Modeling of Developmental Vascular Toxicity. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 15(1):55-63, (2019). https://doi.org/10.1016/j.cotox.2019.04.004

Knudsen, T., T. Zurlinden, K. Saili, AND N. Baker. ToxCast Embryonic Stem Cell (H9) Profiling for Predicting Developmental Toxicity. Presented at Teratology Society's 59th Annual Meeting, San Diego, CA, June 22 - 26, 2019. https://doi.org/10.23645/epacomptox.8862287

2018

Knudsen, T. 20181114 - In Silico Dynamic Models for Developmental Toxicity (FutureTox). FutureTox IV conference, Crystal City, VA, November 14 - 16, 2018.

Knudsen, T. AND G. Daston. 5.22 - Systems Toxicology and Virtual Tissue Models. Chapter 5, Comprehensive Toxicology, 3rd Edition. Elsevier Online, New York, NY, 5:351-362, (2018). https://doi.org/10.1016/B978-0-12-801238-3.95684-8

Knudsen, T. AOP-based ontologies for developmental toxicity. Presented at European Societies of Toxicology (Eurotox) 2018, Brussels, N/A, BELGIUM, September 02 - 05, 2018. https://doi.org/10.23645/epacomptox.7078409

Baker, N. AND T. Knudsen. Abstract Sifter: A literature informatics tool for chemical safety assessments. Presented at Workshop on Strategies and Tools for Conducting Systematic Reviews of Mechanistic Data, Washington, DC, December 10 - 11, 2018. https://doi.org/10.23645/epacomptox.7752308