Science Inventory

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Knudsen, T. Computational Systems Models for Neurovascular Development. 5th International Conference on Developmental Neurotoxicity Testing (DNT5), Konstanz, GERMANY, April 07 - 10, 2024. https://doi.org/10.23645/epacomptox.25602390

Barham, K., R. Spencer, Nancy C. Baker, AND T. Knudsen. Engineering a Computable Epiblast for in silico Modeling of Developmental Toxicity (SOT 24). Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake CIty, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25488040

Kaplan, B., A. Hoberman, W. Slikker, M. Smith, E. Corsini, T. Knudsen, S. Marty, S. Sobrian, S. Fitzpatrick, M. Ratner, AND D. Mendrick. Protecting Human and Animal Health: The Road From Animal Models to New Approach Methods. PHARMACOLOGICAL REVIEWS. American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD, 76(2):251-266, (2024). https://doi.org/10.1124/pharmrev.123.000967

DeWoskin, R., T. Knudsen, AND I. Shah. Virtual Models (aka: in silico or computational models) (Encyclopedia of Toxicology 4th Edition). Philip Wexler (ed.), 4th edition of the Encyclopedia of Toxicology. Academic Press Incorporated, Orlando, FL, 9:779-793, (2024). https://doi.org/10.1016/B978-0-12-824315-2.00094-4

Knudsen, T. Blood-Brain-Barrier Morphogenesis: A Case Example of Rapid Review Approaches Informing Predictive Toxicity Models. Society for Birth Defects Research and Prevention 63rd Annual Conference, Charleston, SC, June 24 - 28, 2023. https://doi.org/10.23645/epacomptox.24250357

Knudsen, T. Computational (in silico) Cellular Dynamics In Developmental Toxicity (GRC 2023). Gordon Research Conference (GRC), Andover, NH, August 13 - 18, 2023. https://doi.org/10.23645/epacomptox.24058668

Knudsen, T. Computational Embryology and Predictive Toxicology - Decoding the Toxicological Blueprint of Embryo Development. Presentation to Symposium in honor of Aldert Piersma¿s Retirement RIVM Nov 2023, Virtual, NC, November 29, 2023. https://doi.org/10.23645/epacomptox.24680157

Knudsen, T. Computational Embryology and Predictive Toxicology ACT Nov 2023). American College of Toxicology (ACT) 44th Annual Conference, Orlando, FL, November 12 - 15, 2023. https://doi.org/10.23645/epacomptox.24592035

Berkhout, J., A. Piersma, J. Legler, A. Gamba, L. Ladeira, B. Staumont, R. Lesage, L. Geris, T. Knudsen, R. Spencer, AND H. Heusinkveld. Computational modeling of neural tube closure defects. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22658674

Knudsen, T. Computational morphodynamics: advanced modeling of human stem cell-derived data. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22704604

Glazier, J., J. Vanin, C. Mahony, AND T. Knudsen. Developing an in silico Virtual Cornea for Predictive Toxicology. 12th World Congress on Alternatives and Animal Use in the Life Sciences (WC12), Niagra, Ontario, CANADA, August 27 - 31, 2023. https://doi.org/10.23645/epacomptox.25678230

Sakamuru, S., D. Ma, J. Pierro, N. Baker, N. Kleinstreuer, J. Cali, T. Knudsen, AND M. Xia. Development and Validation of Enzyme-based CYP26A1 Inhibition Assay in a High-Throughput Screening Platform. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22700743

Knudsen, T. Engineering Complex Systems for Predictive Toxicology in the Animal-free Zone: Modeling Cellular Dynamics in silico. Society of Toxicology, Risk Assessment Specialty Section, NA, NC, April 12, 2023. https://doi.org/10.23645/epacomptox.22670287

Knudsen, T., K. Barham, Nancy C. Baker, K. Carstens, AND R. Spencer. Engineering a Computable Epiblast for in silico Modeling of Developmental Toxicity. 12th World Congress on Alternatives and Animal Use in the Life Sciences, Niagra, Ontario, CANADA, August 27 - 31, 2023. https://doi.org/10.23645/epacomptox.24291223

Barham, K., R. Spencer, Nancy C. Baker, K. Carstens, AND T. Knudsen. Engineering a Computable Model for Microglial-dependent Neurodevelopment. International Neurotoxicology Association, Durham, NC, May 21 - 25, 2023. https://doi.org/10.23645/epacomptox.23271890

Baker, N., J. Pierro, L. Taylor, AND T. Knudsen. Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 40(2):217-236, (2023). https://doi.org/10.14573/altex.2202231

Knudsen, T. Knowledge, Education, and Computational Intelligence. Society for Birth Defects Research and Prevention, 63rd annual meeting, Charleston, SC, June 25 - 28, 2023. https://doi.org/10.23645/epacomptox.23646735

Naphade, O., K. Barham, R. Spencer, Nancy C. Baker, T. Zurlinden, K. Saili, K. Carstens, A. Silvin, F. Ginhoux, AND T. Knudsen. Microglial Dynamics, Blood-Brain Barrier Morphogenesis, and Developmental Toxicity: a brief review and computational model. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 36:100419, (2023). https://doi.org/10.1016/j.cotox.2023.100419

Knudsen, T. Ontologies as the basis for in silico reconstruction of tissue dynamics. Eurotox 2023, Ljubljana, SLOVENIA, September 10 - 13, 2023. https://doi.org/10.23645/epacomptox.24201369

Knudsen, T. Opportunities for Collaboration and Action beyond the Award Period. Presentation to the NAMs STAR Grant Meeting: Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Assessment September 2023Presentation to the NAMs STAR Grant Meeting: Advancing Actionable Alternatives to Vertebrate Animal Testing for Chemical Safety Assessment September 2023, Virtual, NC, September 28, 2023. https://doi.org/10.23645/epacomptox.24235972

Basu, M., K. Howdeshell, S. Rasmussen, K. Rychlik, T. Knudsen, D. Shuey, AND W. Slikker. Society of Birth Defects Research and Prevention’s Multidisciplinary Research Needs Workshop 2022: A Call to Action. Birth Defects Research. John Wiley & Sons, Inc., Hoboken, NJ, 115(10):959-966, (2023). https://doi.org/10.1002/bdr2.2186

Vanin, J., J. Glazier, T. Knudsen, AND C. Mahony. Towards a virtual cornea - an agent-based model to study interactions between the cells and layers of the cornea under homeostasis and following chemical exposure. Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22814429

Knudsen, T., W. Murphy, R. Ashton, J. Fu, F. Ginhoux, H. Heusinkveld, S. Hunter, AND K. Carstens. Computational Biology and Predictive Toxicology of Neurovascular Morphogenesis. EPA Comptox Community of Practice webinar July 2022, NA, NC, July 28, 2022. https://doi.org/10.23645/epacomptox.21375741

Knudsen, T. AND K. Barham. Computational Embryology and Predictive Toxicology. Interagency Modeling and Analysis Group (IMAG) Multiscale Modeling (MSM) Consortium, NA, NC, July 14, 2022. https://doi.org/10.23645/epacomptox.21375654

Pierro, J., B. Ahir, Nancy C. Baker, N. Kleinsteuer, M. Xia, AND T. Knudsen. Computational model for fetal skeletal defects potentially linked to disruption of retinoic acid signaling. Frontiers in Pharmacology. Frontiers, Lausanne, Switzerland, 13:971296, (2022). https://doi.org/10.3389/fphar.2022.971296