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Records 26 to 50 of 72 records from [ORD-NCCT] published between 07/19/2013 and 07/19/2018 from author Keith Houck

2017
Houck, K. Toxicity Testing in the 21st Century EPA’s CompTox Approach (TAMU CVM lecture)EPA’s CompTox Approach (TAMU CVM). Presented at TA&MU CVM lecture, College Station, Texas, April 28, 2017.
Thomas, R., D. Zink, L. Loo, K. Houck, H. Yu, I. Shah, F. Ginhoux, AND T. Knudsen. US EPA - A*Star Partnership - Accelerating the Acceptance of Next-Generation Sciences and Their Application to Regulatory Risk Assessment (A*Star Symposium, Singapore). Presented at A*STAR Symposium, Singapore, Singapore, SINGAPORE, February 04 - 08, 2017.
2016
Judson, R., K. Houck, M. Martin, A. Richard, T. Knudsen, I. Shah, S. Little, J. Wambaugh, Woodrow Setzer, P. Kothiya, J. Phuong, D. Filer, D. Smith, D. Reif, D. Rotroff, N. Kleinstreuer, N. Sipes, M. Xia, R. Huang, K. Crofton, AND R. Thomas. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 152(2):323-339, (2016).
Bone, A., G. Patlewicz, AND K. Houck. Evaluation and comparison of bisphenol A analog activity using ToxCast data (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5176606
Karmaus, A., D. Filer, M. Martin, AND K. Houck. Evaluation of food-relevant chemicals in the ToxCast high-throughput screening program. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 92:188-196, (2016).
Houck, K., A. Karmaus, A. Richard, AND J. Franzosa. Heavy Metals in ToxCast: Relevance to Food Safety (SOT). Presented at SOT, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5084224
Palmer, J., T. Knudsen, L. Egnash, P. Kothiya, K. Houck, AND B. Donley. Human Pluripotent Stem Cell-Based Assay Predicts Developmental Toxicity Potential of ToxCast Chemicals (ACT meeting). Presented at American College of Toxicology, Baltimore, MD, November 06 - 09, 2016. https://doi.org/10.23645/epacomptox.5181325
Simmons, Steve, Eric Watt, K. Paul-Friedman, K. Houck, R. Judson, M. Hornung, AND K. Crofton. Identification of Chemical Features Linked to Thyroperoxidase Inhibition (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155789
Franzosa, J., J. Liu, R. Thomas, J. Wambaugh, K. Houck, AND I. Shah. Prediction of in vivo hepatotoxicity effects using in vitro transcriptomics data (SOT). Presented at SOT annual meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5176498
Richard, A., R. Judson, K. Houck, C. Grulke, P. Volarath, I. Thillainadarajah, C. Yang, J. Rathman, M. Martin, J. Wambaugh, T. Knudsen, K. Mansouri, J. Kancherla, G. Tier, A. Williams, S. Little, K. Crofton, AND R. Thomas. The ToxCast Chemical Landscape - Paving the Road to 21st Century Toxicology. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 29(8):1225-1251, (2016).
Paul-Friedman, K., Eric D. Watt, Michael W. Hornung, Joan M. Hedge, Richard S. Judson, Kevin M. Crofton, Keith A. Houck, AND Steven O. Simmons. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors within the ToxCast Phase I and II Chemical Libraries. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 151(1):160-180, (2016).
Knudsen, T., P. Kothiya, AND K. Houck. Toxcast Profiling in a Human Stem Cell Assay for Developmental Toxicity (SOT). Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016. https://doi.org/10.23645/epacomptox.5155729
Shah, I., Woodrow Setzer, J. Jack, K. Houck, R. Judson, T. Knudsen, J. Liu, M. Martin, D. Reif, Ann M. Richard, Russell S. Thomas, K. Crofton, David J. Dix, AND Robert J. Kavlock. Using ToxCast data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 124(7):910-919, (2016).
2015
Richter, A., J. Brown, B. Bharti, A. Wang, S. Gangwal, K. Houck, E. Hubal, V. Paunov, S. Stoyanov, AND O. Velev. An environmentally benign antimicrobial nanoparticle based on a silver-infused lignin core. Nature Nanotechnology. Nature Publishing Group, London, Uk, 10(9):817-823, (2015).
Houck, K. Analysis of Chemical Bioactivity through In Vitro Profiling using ToxCast and Tox21 High-Throughput Screening (China tox. conf. TATT). Presented at Annual Conference on Toxicological Alternatives and Translational Toxicology, Xi'An, CHINA, July 26 - 29, 2015. https://doi.org/10.23645/epacomptox.5080027
Knudsen, T. B., A. M. Richard, P. G. Kothiya, R. S. Judson, K. A. Houck, K. C. Crofton, R. S. Thomas, S. Little, E. S. Hunter, N. C. Baker, C. K. M. Leung, J. Palmer, A. Smith, M. Colwell, P. West, R. Burrier, AND L. Egnash. Evaluation of 1066 ToxCast Chemicals in a human stem cell assay for developmental toxicity (SOT). Presented at Society of Toxicology, San Diego, CA, March 21 - 26, 2015. https://doi.org/10.23645/epacomptox.5178703
Franzosa, J., J. Jack, P. Kothiya, D. Filer, J. Liu, J. Bonzo, S. Ferguson, I. Shah, A. Richard, R. Thomas, J. Wambaugh, AND K. Houck. Evaluation of In Vitro Biotransformation Using HepaRG Cells to Improve High-Throughput Chemical Hazard Prediction: A Toxicogenomics Analysis (SOT). Presented at 2015 Annual SOT Meeting, San Diego, CA, March 22 - 26, 2015. https://doi.org/10.23645/epacomptox.5178868
Patlewicz, G., K. Houck, R. Judson, A. Richard, I. Shah, AND A. Williams. Exploiting enhanced non-testing approaches to meet the needs for sustainable chemistry. Presented at ACS Meeting, Boston, MA, August 16 - 20, 2015. https://doi.org/10.23645/epacomptox.5077792
Connors, K., D. Filer, N. Sipes, R. Judson, K. Houck, AND M. Martin. High content screening of ToxCast compounds using Vala Sciences’ complex cell culturing systems (SOT). Presented at SOT Annual Meeting, San Deigo, CA, March 22 - 26, 2015. https://doi.org/10.23645/epacomptox.5178847
Wetmore, B., John F. Wambaugh, B. Allen, S. Ferguson, M. Sochaski, R. Woodrow Setzer, Keith A. Houck, C. Strope, K. Cantwell, Richard S. Judson, E. LeCluyse, H. Clewell III, Russell S. Thomas, AND M. Andersen. Incorporating High-Throughput Exposure Predictions with Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, , 1-57, (2015).
Judson, Richard S., F. Magpantay, V. Chickarmane, C. Haskell, N. Tania, J. Taylor, M. Xia, R. Huang, D. Rotroff, D. Filer, K. Houck, M. Martin, N. Sipes, A. Richard, K. Mansouri, Woodrow Setzer, T. Knudsen, K. Crofton, AND R. Thomas. Integrated Model of Chemical Perturbations of a Biological PathwayUsing 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, :1-42, (2015).
Houck, K. Phenotypic Screening of Primary Human Cell Culture Systems to Identify Potential for Compound Toxicity (CHI Phenotypic Screening). Presented at Cambridge Healthtech Institute’s Phenotypic Screening, San Diego, CA, January 26 - 27, 2015. https://doi.org/10.23645/epacomptox.5080015
Franzosa, J., D. Mahapatra, K. Connors, R. Huang, M. Xia, R. Thomas, S. Kullman, AND K. Houck. Quantitative High-Throughput Screening and Orthogonal Assays to Identify Modulators of the Vitamin D Receptor (SETAC). Presented at SETAC, Salt Lake City, UT, November 01 - 05, 2015. https://doi.org/10.23645/epacomptox.5189329