Science Inventory

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Randolph, E., G. Ankley, J. Berninger, J. Cavallin, E. Eid, M. Hughes, M. Kahl, K. Jensen, J. Mayasich, A. Parrella, A. Schroeder, K. Stevens, AND Dan Villeneuve. Evaluating impacts of pulp and paper mill process changes on bioactive contaminant loading to St. Louis Bay. Midwest SETAC, Madison, WI, March 14 - 16, 2016.

Ankley, G., C. LaLone, E. Gray, Dan Villeneuve, AND M. Hornung. Evaluation of the scientific underpinnings for identifying estrogenic chemicals in non-mammalian taxa using mammalian test systems. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(11):2806-2816, (2016).

Cavallin, J., A. Schroeder, B. Blackwell, K. Carlson, K. Jensen, M. Kahl, E. Randolph, Dan Villeneuve, AND G. Ankley. Evaluation of whole mount in situ hybridization as a tool for pathway-based toxicological research in early-life stage fathead minnows (poster). Midwest SETAC, Madison, WI, March 14 - 16, 2016.

Wang, R., A. Biales, N. Garcia-Reyero, E. Perkins, Dan Villeneuve, G. Ankley, AND D. Bencic. Fish Connectivity Mapping: Linking Chemical Stressors by Their MOA-Driven Transcriptomic Profiles. BMC Genomics. BioMed Central Ltd, London, Uk, 17:84, (2016). https://doi.org/10.1186/s12864-016-2406-y

Xia, P., X. Zhang, Y. Xie, M. Guan, Dan Villeneuve, AND H. Yu. Functional toxicogenomic assessment of triclosan in human HepG2 cells using genome-wide CRISPR-Cas9 screen. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 50(19):10682-10692, (2016).

Nelson, K., A. Schroeder, G. Ankley, B. Blackwell, C. Blanksma, S. Degitz, K. Jensen, R. Johnson, M. Kahl, D. Knapen, Pat Kosian, R. Milsk, E. Randolph, T. Saari, E. Stinckens, L. Vergauwen, AND Dan Villeneuve. Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-Mercaptobenzothiazole Part I: Fathead minnow. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 173:192-203, (2016).

Stinckens, E., L. Vergauwen, A. Schroeder, W. Maho, B. Blackwell, H. Witters, R. Blust, G. Ankley, A. Covaci, Dan Villeneuve, AND D. Knapen. Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole - Part II: zebrafish. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 173:204-217, (2016).

Cavallin, J., G. Ankley, B. Blackwell, C. Blanksma, K. Fay, K. Jensen, M. Kahl, D. Knapen, Pat Kosian, S. Poole, E. Randolph, A. Schroeder, L. Vergauwen, AND Dan Villeneuve. Impaired swim bladder inflation in early-life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid. SETAC North America, Orlando, FL, November 06 - 10, 2016.

Arini, A., J. Cavallin, J. Berninger, R. Marfil-Vega, M. Mills, Dan Villeneuve, AND N. Basu. In vivo and in vitro neurochemical-based assessments of wastewater effluents from the Maumee River area of concern. SOCIETY OF ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY JOURNAL. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 211:9-19, (2016).

Pittman, M., C. LaLone, Dan Villeneuve, AND S. Edwards. Informatics approaches in the Biological Characterization of Adverse Outcome Pathways. GEMS Fall Meeting, RTP, NC, November 09, 2016.

Davis, J., D. Ekman, Q. Teng, G. Ankley, J. Berninger, J. Cavallin, K. Jensen, M. Kahl, A. Schroeder, Dan Villeneuve, Z. Jorgenson, K. Lee, AND Tim Collette. Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(10):2493–2502, (2016).

Nguyen, H., H. Zhen, D. Ekman, Dan Villeneuve, J. Cavallin, G. Ankley, Tim Collette, P. Bradley, AND Q. Teng. Monitoring Ecological Impacts of Environmental Surface Waters using Cell-based Metabolomics. SETAC North America 37th Annual Meeting, Orlando, FL, November 06 - 10, 2016.

Cavallin, J., K. Jensen, M. Kahl, Dan Villeneuve, K. Lee, A. Schroeder, J. Mayasich, E. Eid, K. Nelson, R. Milsk, B. Blackwell, J. Berninger, C. LaLone, C. Blanksma, T. Jicha, C. Elonen, R. Johnson, AND G. Ankley. Pathway-based approaches for assessment of real-time exposure to an estrogenic wastewater treatment plant effluent on fathead minnow reproduction. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(3):702-716, (2016).

Watanabe, K., M. Mayo, K. Jensen, Dan Villeneuve, G. Ankley, AND E. Perkins. Predicting fecundity of fathead minnows (Pimephales promelas) exposed toeEndocrine-disrupting chemicals using a MATLAB®-based model of oocyte growth dynamics. PLOS ONE . Public Library of Science, San Francisco, CA, 11(1):26 pgs., (2016).

Berninger, J., C. LaLone, Dan Villeneuve, AND G. Ankley. Prioritization of pharmaceuticals for potential environmental hazard through leveraging a large scale mammalian pharmacological dataset. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(4):1007-1020, (2015).

Poole, S., G. Ankley, B. Blackwell, J. Cavallin, W. Cheng, D. Feifarek, K. Jensen, M. Kahl, E. Randolph, R. Milsk, T. Saari, AND Dan Villeneuve. Quantitative AOP-based predictions for two aromatase inhibitors evaluating the influence of bioaccumulation on prediction accuracy. SETAC North America, Orlando, FL, November 06 - 10, 2016.

Ankley, G., C. Wittwehr, H. Aladjov, H. Byrne, J. de Knecht, E. Heinzle, G. Klambauer, B. Landesmann, M. Luijten, C. MacKay, G. Maxwell, M. Meek, A. Paini, E. Perkins, T. Sobansk, Dan Villeneuve, K. Waters, AND M. Whelan. Role of adverse outcome pathways in developing computational models for regulatory toxicology. SETAC North America, Orlando, FL, November 06 - 10, 2016.

Teng, Q., D. Ekman, H. Zhen, Dan Villeneuve, J. Cavallin, J. Davis, G. Ankley, AND Tim Collette. Screening ecological impacts of environmental surface waters using cell-based metabolomics. SETAC North America 37th Annual Meeting, Orlando, FL, November 06 - 10, 2016.

LaLone, C., Dan Villeneuve, H. Helgen, D. Lane, S. Walata, K. Nelson, S. Robinson, J. Swintek, AND G. Ankley. Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A web-based tool for addressing the challenges of cross-species extrapolation of chemical toxicity. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 153(2):228-245, (2016).

Burns, F., L. Cogburn, G. Ankley, Dan Villeneuve, E. Waits, Y. Chang, V. Llaca, S. Deschamps, R. Jackson, AND R. Hoke. Sequencing and De novo Draft Assemblies of the Fathead Minnow (Pimphales promelas)Reference Genome. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 35(1):212-217, (2016).

Perkins, E., N. Garcia-Reyero, S. Edwards, C. Wittwehr, Dan Villeneuve, D. Lyons, AND G. Ankley. The Adverse Outcome Pathway: A conceptual framework to support toxicity testing in the 21st century. Chapter 1, Computational Systems Toxicology: Discovering and Using the Toxicological Blueprint of Active Substances. Springer Science + Business Media, New York, NY, , 1-26, (2015).

Peng, Y., P. Xia, J. Zhang, Dan Villeneuve, J. Zhang, Z. Wang, S. Wei, H. Yu, AND X. Zhang. Toxicogenomic assessment of 6-OH-BDE47 induced developmental toxicity in chicken embryo. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 50(22):12493-12503, (2016).

Stinkens, E., L. Vergauwen, J. Cavallin, A. Schroeder, W. Maho, B. Blackwell, H. Witters, R. Blust, G. Ankley, A. Covaci, D. Volz, Dan Villeneuve, AND D. Knapen. Validation of the AOP network “Thyroperoxidase and/or deiodinase inhibition leading to impaired swim bladder inflation”. Fish and Amphibian Embryo Symposiuim, Paris, FRANCE, December 01 - 02, 2016.

LaLone, C., R. Milsk, Dan Villeneuve, K. Garber, K. Sappington, J. Housenger, AND G. Ankley. Weight-of-evidence evaluation of an adverse outcome pathway network linking activation of the nicotinic acetylcholine receptor in bees to colony loss. SETAC North America, Orlando, FL, November 06 - 10, 2016.

Conolly, R., W. Cheng, Dan Villeneuve, G. Ankley, D. Miller, K. Watanabe, AND M. Mayo. A Quantative Adverse Outcome Pathway Linking Aromatase Inhibition in Fathead Minnows with Population Dynamics. Society of Toxicology, San Diego, CA, March 22 - 27, 2015.