Main Title |
Role of Inhaled Particles in the Pathophysiology of Cardiovascular Disease. |
Author |
M. Kleinman
|
CORP Author |
California Univ., Irvine.; California State Air Resources Board, Sacramento. Research Div.; California Environmental Protection Agency, Sacramento. |
Year Published |
2010 |
Report Number |
CARBRA-04-320; ARB/R10-904 |
Stock Number |
PB2011-100258 |
Additional Subjects |
Inhalation ;
Particulates ;
Pothophysiology ;
Cardiovascular disease ;
Respiratory systems ;
Air pollution effects(Animals) ;
Environmental exposure ;
Atherosclerosis ;
Biomarkers ;
Mice ;
Laboratory animals ;
Heart disease ;
California
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB2011-100258 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
56p |
Abstract |
The mechanisms by which particulate matter (PM) exposure disrupts cardiac function and worsens cardiovascular disease (CVD) are not well understood. There is a growing body of knowledge that suggests that PM exposure can induce inflammatory changes in blood vessels and exacerbate atherogenesis leading to the development of atherosclerotic plagues and lesions. We hypothesized that PM exposure would abnormally activate endothelial cells and induce vascular inflammation that will lead to the accelerated formation of arterial plagues which are a hallmark of atherosclerosis. |
Supplementary Notes |
Sponsored by California State Air Resources Board, Sacramento. Research Div. and California Environmental Protection Agency, Sacramento. |
Availability Notes |
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PUB Date Free Form |
May 2010 |
Category Codes |
68G; 68A; 57E |
NTIS Prices |
PC A05/MF A05 |
Document Type |
NT |
Medium |
Final rept |
Cataloging Source |
NTIS/MT |
Control Number |
110200650 |
Origin |
NTIS |
Type |
CAT |