Main Title |
Cholinesterase Response and Symptomatology from Exposure to Organic Phosphorus Insecticides. |
Author |
Sumerford, W. Taylor ;
Hayes, Jr., Wayland J. ;
Johnston, J. Monte ;
Walker, Kenneth ;
Spillane., Janet ;
|
CORP Author |
Communicable Disease Center, Atlanta, Ga. |
Year Published |
1953 |
Stock Number |
PB-278 085 |
Additional Subjects |
Cholinesterase ;
Pesticides ;
Industrial medicine ;
Insecticides ;
Toxicology ;
Phosphorus organic compounds ;
Exposure ;
Signs and symptoms ;
Tables(Data) ;
Physiological effects ;
Responses ;
Humans ;
Reprints ;
Occupational safety and health ;
Toxic substances
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB-278 085 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
16p |
Abstract |
In 1951, 258 persons with different degrees of agricultural exposure to organic phosphorus insecticides were studied in regard to blood cholinesterase values and symptomatology. The average cholinesterase values for groups known to have definite and consistent exposure showed significant reduction during the period of exposure. Average erythrocyte enzyme values for mixing-plant personnel, commercial applicators, and part-time applicators were 0.46, 0.65, and 0.69, respectively, as compared with 0.72, the lowest average value found for any group during the preexposure period. The average cholinesterase values for groups with little or no exposure to insecticides remained normal or showed changes so small that their significance is in doubt. Although extensive day-to-day exposure was regularly associated with reduced blood cholinesterase, the only fatal and near-fatal cases which were found were associated with brief, massive exposure and gross carelessness. Illness characterized by myosis or by any three of a group of selected symptoms was considered suggestive of poisoning but not absolutely diagnostic of it in isolated cases. Such illness was increased in the definitely exposed groups during the period of their exposure. |
Supplementary Notes |
Pub. in A. M. A. Archives of Industrial Hygiene and Occupational Medicine, v7 p383-398, May 53. |
Availability Notes |
Included in the report, Journal Articles on Toxicology. Group 3, PB-278 081. |
Title Annotations |
Reprint: Cholinesterase Response and Symptomatology from Exposure to Organic Phosphorus Insecticides, |
PUB Date Free Form |
1953 |
Category Codes |
6J; 6T; 57U; 57Y; 68G; 68E |
NTIS Prices |
(Order as PB-278 081, MF A01) |
Primary Description |
500/01 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
323735776 |
Origin |
NTIS |
Type |
CAT |