| Main Title |
Results of Several Investigations with Propionic Acid with Cover Letter dated 10/06/87. |
| CORP Author |
BASF Corp., Wyandotte, MI., Chemicals Div.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
9 Oct 1987 |
| Year Published |
1987 |
| Report Number |
FYI-OTS-1087-0579; |
| Stock Number |
OTS-0000579-0 |
| Additional Subjects |
Teratogenic compounds ;
Assaying ;
Propionic acid ;
Toxicity ;
Canines ;
Histopathology ;
Toxicology ;
Plastics ;
Rats ;
BASF(Trademark) ;
Bundesgesundheitsamt
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0000579-0 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
BASF Corporation (formerly BASF Wyandotte Corporation) holds FIFRA Registration 7969-33, Luprosil, a preservative for field-shelled corn, the active ingredient of which is propionic acid. In addition, BASF Corporation is also a processor of propionic acid which is being purchased in the U.S. for chemical use in plastics production. This submission is to inform EPA of new preliminary results from toxicological investigations on propionic acid. This information and the enclosure have been supplied to us by our ultimate parent corporation, BASF Aktiengesellschaft. The German Federal Health Office (Bundesgesundheitsamt) has recently undertaken to evaluate propionic acid. In a meeting on May 13, 1987, in which numerous toxicologists and pathologists participated, the results of the following investigations with propionic acid were discussed. (1) Histopathological evaluation of a long-term feeding experiment carried out by GRIEM of the Bundesgesundheitsamt, the first results of which had been published in 1985; (2) A 90-day feeding study in rats with two recovery periods of 90 and 180 days carried out by ALTMANN et al., also of the Bundesgesundheitsamt; (3) A 3-month feeding study in dogs with a 6-week recovery period (0.3, 1, and 3% propionic acid in the feed) carried out by HELLWIG et al., at BASF's toxicology laboratory and jointly sponsored by BASF Aktiengesellschaft and BF Chemicals International. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
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| Category Codes |
57Y; 57B; 57E; 68G |
| NTIS Prices |
PC A01/MF$25.00 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
019102800 |
| Origin |
NTIS |
| Type |
CAT |
