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RECORD NUMBER: 291 OF 1187Main Title | Effect of Water Pollutants and Other Chemicals upon Ribonuclease Activity In vitro. | |||||||||||
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Author | Christensen, G. M. ; Olson, D. L. ; | |||||||||||
CORP Author | Environmental Research Lab.-Duluth, MN. | |||||||||||
Year Published | 1980 | |||||||||||
Report Number | EPA-600/J-81-553; | |||||||||||
Stock Number | PB82-207804 | |||||||||||
Additional Subjects | Ribonuclease ; Water pollution ; In vitro analysis ; Enzymes ; Activity ; Inhibitors ; Chemical compounds ; Palladium ; Gold ; Reprints ; Heavy metals | |||||||||||
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Collation | 9p | |||||||||||
Abstract | Ribonuclease was treated in vitro with 73 chemicals, many of which are environmental pollutants, including inorganic, organic, and metal-organic chemicals, pesticides, and other biocides, alkyl and aryl industrial pollutants, and certain additional chemicals, to determine their effect upon enzyme activity. Palladium (II and IV) and gold (III) were the strongest inhibitors of RNase activity. Other strong inhibitors, in decreasing order of effect, were: sodium dodecyl sulfate, silver (I), EDTA, mercury (II), copper (II), thiram (fungicide), platinum (IV), malathion (pesticide), lead (II), and beryllium (II). Intermediate effects were found with other inorganic cations, many anions, and some other chemicals. A number of compounds of different chemical types caused no measurable effect. None of the chemicals tested caused a measurable activation of this enzyme. | |||||||||||
Supplementary Notes | Pub. in Environmental Research 26, p274-280 1981. | |||||||||||
NTIS Title Notes | Journal article. | |||||||||||
Title Annotations | Reprint: Effect of Water Pollutants and Other Chemicals upon Ribonuclease Activity In vitro. | |||||||||||
PUB Date Free Form | 12 Apr 80 | |||||||||||
Category Codes | 6T; 6F; 57Y; 68D | |||||||||||
NTIS Prices | PC A02/MF A01 | |||||||||||
Primary Description | 600/03 | |||||||||||
Document Type | NT | |||||||||||
Cataloging Source | NTIS/MT | |||||||||||
Control Number | 323815243 | |||||||||||
Origin | NTIS | |||||||||||
Type | CAT |