Main Title |
Biochemical Changes in Humans upon Exposure to Sulfuric Acid Aerosol and Exercise. |
Author |
Chaney, Suzanne ;
Blomquist, Wendy ;
Muller, Keith ;
Goldstein, George ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1980 |
Report Number |
EPA-600/J-80-400; |
Stock Number |
PB83-153726 |
Additional Subjects |
Sulfuric acid ;
Toxicology ;
Aerosols ;
Humans ;
Exercise(Physiology) ;
Exposure ;
Reprints ;
Air pollution effects(Humans)
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB83-153726 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
8p |
Abstract |
This study evaluated the effect of a single exposure to sulfuric acid aerosol on six human biochemical blood parameters. A total of 18 human subjects were exposed to ambient air for 4 hr on the first day of exposure and to 100 micrograms/cu. m. (0.033 micro M) sulfuric acid aerosol (0.5 micrometers mean mass diameter) for 4 hr on the second day. A total of 17 human subjects were exposed for 4 hr to ambient air on both exposure days. On each exposure day, at 30 min and 90 min after exposure was initiated, all subjects engaged in a 15-min exercise period (walking 4 mph on atreadmill inclined at 10 degrees). Six biochemical blood parameters were measured before and after exposure: glutathione, lysozyme, glutatione reductase, serum glutamic exaloacetic acid transaminase, serum vitamin E, and 2,3-diphosphoglyceric acid. The results indicate no significant effect of one 4-hr exposure of humans to 100 micrograms/cu. m. sulfuric acid aerosol. One significant post-exposure effect did occur--an increase in glutathione reductase--for both the control and acid-exposured group. It is concluded that at the levels studied, sulfuric acid aerosol is neutralized in the upper airways; consequently, no cellular damage is measurable. |
Supplementary Notes |
Pub. in Archives of Environmental Health, v35 n4 p211-216 Jul/Aug 80. See also PB80-108582. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Biochemical Changes in Humans upon Exposure to Sulfuric Acid Aerosol and Exercise. |
PUB Date Free Form |
1980 |
Category Codes |
6T; 6F; 57Y; 68A |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
307822493 |
Origin |
NTIS |
Type |
CAT |