| Main Title |
Mutagenic Assay of T-1716AC Aerosol with and without Metabolic Activation with Cover Letter. |
| CORP Author |
Industrial Bio-Test Labs., Inc., Northbrook, IL. ;Minnesota Mining and Mfg. Co., St. Paul.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
3 Dec 1982 |
| Year Published |
1982 |
| Report Number |
878211462; |
| Stock Number |
OTS-0205948 |
| Additional Subjects |
Toxicity ;
Aerosols ;
Air pollution ;
Bioassay ;
Rats ;
Liver ;
Methyl chloride ;
Assaying ;
Chemical compounds ;
Microsomes ;
Solvents ;
Trichloroethane ;
Testing ;
Mutagenicity tests ;
Metabolic activation
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0205948 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
19p |
| Abstract |
T-1716AC at a concentration of 1.9 gm (1 sec. discharge) in the absence of rat liver microsomes is moderately mutagenic. In the presence of metabolic activation the level of base-pair substitution is increased by a factor of 4 I/Z, approximately. No significant mutagenic effect occurred with T-716AC in the absence of the mammalian microsomes but a convincing evidence of mutagenic effect was obtained in the presence of rat liver microsomes. Methyl chloride used as a positive volatile control was highly mutagenic with or without the rat liver microsomes. 1, 1, 1-Trichloroethane is contained in. T-1716AC. However the concentration of this solvent is not indicated. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| Category Codes |
57Y; 57F; 68A |
| NTIS Prices |
PC A03/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
009400880 |
| Origin |
NTIS |
| Type |
CAT |
