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OLS Field Name OLS Field Data
Main Title Modeling the Accumulation of Three Waterborne Chlorinated Ethanes in Fathead Minnows ('Pimephales promelas'): A Physiologically Based Approach.
Author Lien, G. J. ; Nichols, J. W. ; McKim, J. M. ; Gallinat, C. A. ;
CORP Author Environmental Research Lab.-Duluth, MN. ;AScI Corp., Duluth, MN.
Publisher c1994
Year Published 1994
Report Number EPA/600/J-94/354;
Stock Number PB94-210416
Additional Subjects Water pollution effects(Animals) ; Chlorinated hydrocarbons ; Ethane ; Pharmacokinetics ; Chemical models ; Regional blood flow ; Skin(Anatomy) ; Physiology ; Reprints ; Pimephales promelas ; Minnows ; Ethane/1-1-2-2-tetrachloro ; Ethane/pentachloro ; Ethane/hexachloro
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NTIS  PB94-210416 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 11/11/1994
Collation 14p
Abstract A physiologically based kinetic model was used to predict the accumulation of a homologous series of chlorinated ethanes in fathead minnows (Pimephales promelas). Uptake and accumulation of these compounds are described in terms of a few fundamental physiological, morphological, and physicochemical parameters. Chemical residues in 30-d-old fathead minnows exposed to 1,1,2,2-tetrachloroethane, pentachloroethane, and hexachloroethane were used to evaluate model performance. The predicted and observed accumulations of the chlorinated ethanes were in close agreement. A quantitative assessment of the major factors regulating the exchange of these compounds indicates that the cutaneous surface may be an important route of uptake in small fish.
Supplementary Notes Pub. in Environmental Toxicology and Chemistry, v13 n7 p1195-1205 1994. Prepared in cooperation with AScI Corp., Duluth, MN.
NTIS Title Notes Journal article.
Title Annotations Reprint: Modeling the Accumulation of Three Waterborne Chlorinated Ethanes in Fathead Minnows ('Pimephales promelas'): A Physiologically Based Approach.
Category Codes 68D; 57Y
NTIS Prices PC A03/MF A01
Primary Description 600/03
Document Type NT
Cataloging Source NTIS/MT
Control Number 428724473
Origin NTIS
Type CAT