| Main Title |
Progress Report on Tetrachlorobenzene: Skin Absorption in the Rabbit and Metabolism in the Rat with Cover Letter. |
| CORP Author |
Dow Chemical Co., Midland, MI.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
2 Dec 1969 |
| Year Published |
1969 |
| Report Number |
878211085; |
| Stock Number |
OTS-0206149 |
| Additional Subjects |
Toxicity ;
Chlorinated benzenes ;
Metabolism ;
Skin absorption ;
Gas-liquid chromatography ;
Absorption ;
Distribution ;
Metabolism ;
Laboratory animals ;
Rats ;
Rabbits ;
Skin irritation ;
Detection ;
Benezen/tetrachloro ;
CAS No 95-94-3 ;
CAS No 634-66-2
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0206149 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
239p |
| Abstract |
1,2,3,4 and 1,2,4,5-tetrachlorobenzene are intermediates in the synthesis of various chlorinated compounds. Since personnel are being exposed to tetrachlorobenzene in the plant, studies on absorption, distribution and metabolism need to be conducted. Samples of 1,2,3,4 and 1,2,4,5-tetrachlorobenzene were analyzed by electron-capture gas-liquid chromatography and nuclear magnetic resonance. The results indicate that the samples are 94.9% 1,2,3,4 and 98.7% 1,2,4,5-tetrachlorobenzene. Gas-liquid chromatography, using an electron-capture detector, was found to be a very sensitive method for detection of tetrachlorobenzene. Amounts as small as 0.01 microg have been detected. The column used was alkaline carbowax 20 M on regular chromosorb (60-80 mesh), with a column temperature of 190 degrees C and an injector temperature of 215 degrees C. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
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| Category Codes |
57Y; 68G; 57U; 44G |
| NTIS Prices |
PC A12/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
009400500 |
| Origin |
NTIS |
| Type |
CAT |
