Main Title |
Approach to Identifying Specialized Batteries of Bioassays for Specific Classes of Chemicals: Class Analysis Using Mutagenicity and Carcinogenicity Relationships and Phylogenetic Concordance and Discordance Patterns. 1. Composition and Analysis of the Overall Data Base. A Report of Phase 2 of the U.S. Environmental Protection Agency Gene-Tox Program. |
Author |
Ray, V. A. ;
Kier, L. D. ;
Kannan, K. L. ;
Haas, R. T. ;
Auletta, A. E. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Pfizer Central Research, Groton, CT. ;Monsanto Co., St. Louis, MO. ;Oak Ridge National Lab., TN. |
Year Published |
1987 |
Report Number |
EPA/600/J-87/296; |
Stock Number |
PB88-185129 |
Additional Subjects |
Bioassay ;
Carcinogens ;
Mutagens ;
Chemical analysis ;
Toxicity ;
Data processing ;
Comparison ;
Chemical compounds ;
Testing ;
Reprints ;
Data bases
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB88-185129 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
47p |
Abstract |
The major utility and/or benefit of this compilation will be derived from a chemical class by chemical class comparative analysis of individual assay performance. The data base will serve as a resource for hazard evaluation of chemicals through structural correlations and biological end points and associated end points such as carcinogenicity. An example analysis is presented using chemical Class 5 (alkyl sulfates sulfoxides, sulfones, sulfonates, organic sulfur compounds not otherwise classified) and includes the four components. (Copyright (c) Elsevier Science Publishers B.V. (Biomedical Division).) |
Supplementary Notes |
Pub. in Mutation Research 185, n3 p197-241 May 87. Prepared in cooperation with Pfizer Central Research, Groton, CT., Monsanto Co., St. Louis, MO., and Oak Ridge National Lab., TN. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Approach to Identifying Specialized Batteries of Bioassays for Specific Classes of Chemicals: Class Analysis Using Mutagenicity and Carcinogenicity Relationships and Phylogenetic Concordance and Discordance Patterns. 1. Composition and Analysis of the Overall Data Base. A Report of Phase 2 of the U.S. Environmental Protection Agency Gene-Tox Program. |
PUB Date Free Form |
c1987 |
Category Codes |
57Y; 68G; 57B; 99A |
NTIS Prices |
PC A03/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
816222948 |
Origin |
NTIS |
Type |
CAT |