Main Title |
Critical Study of the Manometric Assay of Cholinesterase in Rat Blood. |
Author |
Witter., Robert F. ;
|
CORP Author |
Communicable Disease Center, Atlanta, Ga. |
Year Published |
1961 |
Stock Number |
PB-275 929 |
Additional Subjects |
Cholinesterase ;
Chemical analysis ;
Assaying ;
Blood chemical analysis ;
Manometers ;
Enzymes ;
Rats ;
Laboratory animals ;
Tables(Data) ;
Esterases ;
Hydrolases ;
Age ;
Reprints
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB-275 929 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
11p |
Abstract |
A study was made of the conditions necessary for the quantitative assay of the erythrocyte and plasma cholinesterases of the rat by the Warburg manometric method. Butyrylcholine, acetyl-beta-methylcholine, and acetylcholine were tested as substrates, but only acetylcholine proved satisfactory. The level of the red cell cholinesterase did not change with age of the rat. The erythrocytes were found to contain an esterase which hydrolyzes butyrylcholine. In confirmation of other workers, it was found that the plasma cholinesterase levels of female rats increase with age and are higher than those of male rats of all ages and that the plasma of male animals contains an approximately equal mixture of true and pseudocholinesterase whereas that of female rats contains mainly pseudocholinesterase. |
Supplementary Notes |
Pub. in Toxicology and Applied Pharmacology, v4 n3 p313-323, May 62. |
Availability Notes |
Included in the report, Journal Articles on Pesticide Biology, PB-275 918. |
Title Annotations |
Reprint: A Critical Study of the Manometric Assay of Cholinesterase in Rat Blood, |
PUB Date Free Form |
1 Sep 61 |
Category Codes |
6A; 7D; 57B; 99A |
NTIS Prices |
(Order as PB-275 918, MF A01) |
Primary Description |
500/01 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
323729993 |
Origin |
NTIS |
Type |
CAT |