| Main Title |
Incomplete Studies with Cover Letter. |
| CORP Author |
Mobil Oil Corp., New York.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
20 Aug 1982 |
| Year Published |
1982 |
| Report Number |
878210559; |
| Stock Number |
OTS-0206118 |
| Additional Subjects |
Mutagenesis ;
Toxicity ;
Rats ;
Liver ;
Metabolic activation ;
Toxicology ;
Bacteria ;
Assays ;
Homogenates ;
Doses ;
Chlorinated paraffins ;
Salmonella
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0206118 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
31p |
| Abstract |
XRR 185A (TACU no. 8259) was tested in the Ames Salmonella Pre-Incubation Assay with metabolic activation by Aroclor 1254 induced rat liver homogenate (S-9) at doses of 1.0 micro1, 0.50 micro1, 0.30 micro1, 0.10 microl and 0.05 microl test substance per bacterial plate and without metabolic activation by S-9 at doses of 0.10 micro1, 0.07 microl, D.05 microl, 0.03 micro1 and 0.01 micro1 test substance per bacterial plate in strains TA98, TA100, TA1535, TA1537 and TA1538. In preliminary toxicity studies at a dose of 0.30 microl/50 microl without S-9 in tester strains TA100 and TA1537 the background bacterial lawn was extremely reduced and microcolonies were present. In both of these tester strains at a dose of 3.1 microl/50 microl with S-9 the background bacterial lawn was moderately reduced. The reduction of the background bacterial lawn and the presence of microcolonies indicate sufficient solubility for interaction of the bacteria with the test material . The results of the assay indicate that XRR 185A had no mutagenic activity in this test system. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
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| Category Codes |
57Y |
| NTIS Prices |
PC A04/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
009400390 |
| Origin |
NTIS |
| Type |
CAT |
