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RECORD NUMBER: 37 OF 40

Main Title Role of Inhaled Particles in the Pathophysiology of Cardiovascular Disease.
Author M. Kleinman
CORP Author California Univ., Irvine.; California State Air Resources Board, Sacramento. Research Div.; California Environmental Protection Agency, Sacramento.
Year Published 2010
Report Number CARBRA-04-320; ARB/R10-904
Stock Number PB2011-100258
Additional Subjects Inhalation ; Particulates ; Pothophysiology ; Cardiovascular disease ; Respiratory systems ; Air pollution effects(Animals) ; Environmental exposure ; Atherosclerosis ; Biomarkers ; Mice ; Laboratory animals ; Heart disease ; California
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NTIS  PB2011-100258 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 56p
Abstract The mechanisms by which particulate matter (PM) exposure disrupts cardiac function and worsens cardiovascular disease (CVD) are not well understood. There is a growing body of knowledge that suggests that PM exposure can induce inflammatory changes in blood vessels and exacerbate atherogenesis leading to the development of atherosclerotic plagues and lesions. We hypothesized that PM exposure would abnormally activate endothelial cells and induce vascular inflammation that will lead to the accelerated formation of arterial plagues which are a hallmark of atherosclerosis.
Supplementary Notes Sponsored by California State Air Resources Board, Sacramento. Research Div. and California Environmental Protection Agency, Sacramento.
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PUB Date Free Form May 2010
Category Codes 68G; 68A; 57E
NTIS Prices PC A05/MF A05
Document Type NT
Medium Final rept
Cataloging Source NTIS/MT
Control Number 110200650
Origin NTIS
Type CAT