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Main Title Laboratory Evaluation of Marine Fishes as Carcinogen Assay Subjects.
Author Couch, John A. ; Courtney, Lee A. ; Foss, Steven ;
CORP Author Environmental Research Lab., Gulf Breeze, FL.
Year Published 1981
Report Number EPA-600/D-80-039 ;ERL.GB-0101;
Stock Number PB82-205824
Additional Subjects Carcinogens ; Pesticides ; Invertebrates ; Risk ; Bioassay ; Fishes ; Marine biology ; Cyprinodon variegatus ; Carcinogenesis ; Trifluralin ; Dysplasia
Library Call Number Additional Info Location Last
NTIS  PB82-205824 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 17p
Abstract The U.S. Environmental Protection Agency (EPA) and the National Cancer Inst. (NCI) have major responsibilities for determining the fate and risks of carcinogenic agents in the natural environment. Under the auspices of EPA/NCI, the Carcinogen Research Team at the USEPA Lab, Gulf Breeze, has a major role in investigating the fate, effects, and risks of carcinogenic agents in the aquatic portion of the biosphere. In regard to this role, there is a need for practical, experimental exposure systems for the short term, and long term exposure of fishes and invertebrates in order to evaluate their responses to environmentally significant carcinogens. A pilot test of the system has been completed. This test utilized flowing filtered, estuarine water, controlled water temperature, controlled photo period, controlled nutrition of test species, oxygen concentration monitoring, and various life cycle stages of the test fish, the sheepshead minnow, Cyprinodon variegatus, and the suspect carcinogenic herbicide, trifluralin. Continuous exposures to 1 to 5 micrograms/1 trifluralin were conducted with zygote, thru embryogenesis to adult stages of the fish.
Supplementary Notes Pub. in Phyletic Approaches to Cancer (Japan Sci. Soc. Press, Tokyo), p125-139 1981.
NTIS Title Notes Book chapter.
PUB Date Free Form 1981
Category Codes 6T; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/04
Document Type NT
Cataloging Source NTIS/MT
Control Number 323814752
Origin NTIS
Type CAT