Main Title |
Selected approaches to risk assessment for multiple chemical exposures : progress report on guideline development at ECAO-Cincinnati / |
Author |
Stara, J. F. ;
Erdreich, L. S.
|
Other Authors |
|
CORP Author |
Environmental Protection Agency, Cincinnati, OH. Environmental Criteria and Assessment Office. |
Publisher |
Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, |
Year Published |
1984 |
Report Number |
EPA-600/9-84-014 a |
Stock Number |
PB84-226992 |
OCLC Number |
11837324 |
Subjects |
Environmental health--United States ;
Carcinogens ;
Pollution--United States ;
Pollution--Environmental aspects--United States ;
Chemicals--Environmental aspects--United States
|
Additional Subjects |
Chemical compounds ;
Public health ;
Guidelines ;
Meetings ;
Environmental surveys ;
Dosage ;
Exposure ;
Risk ;
Assessments ;
Mathematical models ;
Toxic substances ;
Pharmacokinetics
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EHAM |
EPA-600/9-84-014 a |
|
Region 1 Library/Boston,MA |
05/25/2016 |
EJBD |
EPA 600/9-84-014a |
|
Headquarters Library/Washington,DC |
04/18/2016 |
EKBD |
EPA-600-9-84-014a |
|
Research Triangle Park Library/RTP, NC |
11/18/2005 |
EKCD |
EPA-600/9-84-014a |
|
CEMM/GEMMD Library/Gulf Breeze,FL |
09/24/2018 |
ELBD ARCHIVE |
EPA 600/9-84-014a |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
ESAD |
EPA 600-9-84-014A |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
NTIS |
PB84-226992 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
x, 103 pages : illustrations ; 28 cm |
Abstract |
This report summarizes the second of a series of workshop meetings on methods for assessing human health risks from exposure to chemical mixtures sponsored by the Environmental Criteria and Assessment Office (ECAO) of the U.S. Environmental Protection Agency, July 12-13, 1983. The first workshop 'Approaches to Risk Assessment for Multiple Chemical Exposures' held in September, 1982 provided a basis for selecting methods to develop into risk assessment guidelines. Five issues were reviewed at this meeting: (1) inter-species conversion of dose and duration of exposure, (2) assessment of risk for less than lifetime exposure to carcinogens and to other toxicants, (3) additivity model for chemical mixtures, (4) methods for determination of acceptable daily intakes from quantal of continuous data, and (5) pharmacokinetic basis of route-to-route conversions. Working groups also produced recommendations for approaches to four additional problems: consideration of high risk subgroups, assessment of multiple routes of exposure, ranking the severity of effects and the use of exposure and monitoring data in health risk assessment. A symposium on this methodology is planned for the fall of 1984. |
Notes |
Distributed to despository libraries in microfiche. "June 1984." Includes bibliographical references (pages 101-103). "EPA-600/9-84-014a." |