Record Display for the EPA National Library Catalog
RECORD NUMBER: 3 OF 5Main Title | Evaluation of the potential carcinogenicity of gamma-hexachlorocyclohexane (Lindane) (50-09-9) / | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CORP Author | Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. | |||||||||||
Publisher | U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; | |||||||||||
Year Published | 1988 | |||||||||||
Report Number | EPA/600/8-91/081; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-042 | |||||||||||
Stock Number | PB93-185064 | |||||||||||
Subjects | Aromatic compounds--Carcinogenicity ; Gamma-Hexchlorocyclohexane--Carcinogenicity ; Lindane--Carcinogenicity | |||||||||||
Additional Subjects | Benzene hexachloride ; Carcinogens ; Toxicity ; Humans ; Animals ; Risk assessment ; Dose-response relationships ; Carcinogenicity tests ; CAS-58-89-9 | |||||||||||
Holdings |
|
|||||||||||
Collation | 25 pages ; 28 cm | |||||||||||
Abstract | Gamma-Hexachlorocyclohexane (gamma-BHC or Lindane) is a probable to possible human carcinogen, classified as weight-of-evidence Group B2/C under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient to Limited, and the evidence from human studies is Inadequate. The potency factor (F) for gamma-BHC is estimated to be 7.39/(mg/kg/day), placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, gamma-BHC is assigned a MEDIUM hazard ranking for the purposes of RQ adjustment. (When the weight-of-evidence is expressed as a range, the hazard ranking is based on the higher weight-of-evidence group.) |
|||||||||||
Notes | Cover title. "June 1988." Includes bibliographical references. Microfiche. |