Record Display for the EPA National Library Catalog
RECORD NUMBER: 302 OF 1609Main Title | Biochemical changes in humans upon exposure to sulfuric acid aerosol and exercise / | ||||||||||||||||||||||||||
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Publisher | Health Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, | ||||||||||||||||||||||||||
Year Published | 1979 | ||||||||||||||||||||||||||
Report Number | EPA-600/1-79-032 | ||||||||||||||||||||||||||
Stock Number | PB80-108582 | ||||||||||||||||||||||||||
OCLC Number | 47899451 | ||||||||||||||||||||||||||
Subjects | Sulfuric acid--Health aspects | ||||||||||||||||||||||||||
Additional Subjects | Sulfuric acid ; Exercise(Physiology) ; Toxicology ; Aerosols ; Humans ; Exposure ; Biochemistry ; Blood ; Concentration(Composition) ; Physiological effects ; Glutathione ; Tocopherol ; Nitrogen organic compounds ; Phosphorus organic compounds ; Air pollution effects(Humans) ; Toxic substances ; Reductases/glutathione ; Aminotransferases/aspartate ; Diphosphoglyceric acid | ||||||||||||||||||||||||||
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Collation | iv, 19 p. ; 28 cm. | ||||||||||||||||||||||||||
Abstract | A total of 18 human subjects were exposed to ambient air for four hours on the first day of exposure and to four hours of 100 micrograms/cu. m. (0.033 micromole) sulfuric acid aerosol exposed to four hours of ambient air on both exposure days. Six biochemical blood parameters were measured pre and post exposure: glutathione, lysozyme, glutathione reductase, serum glutamic oxaloacetic acid transaminase, serum vitamin E and 2,3-diphosphoglyceric acid. The results indicate no significant effect of one four hour exposure of humans to sulfuric acid aerosol (100 micrograms/cu. m.). One significant effect did occur indicating an increase in glutathione reductase post exposure for both the control group and acid group. This report covers a period from October 23, 1978, to December 15, 1978, and work was completed as of May 1, 1979. |
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Notes | "Clinical Pathology Branch, Clinical Studies Division, Health Effects Research Laboratory." "August 1979." Includes bibliographical references (p. 8-9). "EPA-600/1-79-032." |