Record Display for the EPA National Library Catalog
RECORD NUMBER: 4162 OF 4354| Main Title | Validation of Human Eye Irritation by Tear Lysozyme Levels. | |||||||||||
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| Author | Pietsc, Richard L. ; | |||||||||||
| CORP Author | Duke Univ., Durham, N.C. | |||||||||||
| Year Published | 1972 | |||||||||||
| Report Number | EPA-68-02-0096; 1362; | |||||||||||
| Stock Number | PB-224 537 | |||||||||||
| Additional Subjects | ( Air pollution ; Eye injuries) ; ( Eye injuries ; Smog) ; ( Body fluids ; Eye(Anatomy)) ; Ophthalmology ; Experimental data ; Questionnaires ; Muramidase ; Conjunctiva ; Oxidizers ; Degradation ; Humans ; Bioassay ; Enzymes ; Public health ; California ; Tears(Physiology) | |||||||||||
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| Collation | 19p | |||||||||||
| Abstract | Tear samples were collected from 358 volunteers in Southern California in smog polluted areas. No consistent variation of lysozyme concentration with oxidant concentration was demonstrated. Subjects exposed to .19 ppm of oxidant in the open air did show decreased lysis. A threshold effect is possible. No correlation was established between lysis and mild subjective complaints of irritation. Objective indications of eye irritation show a mild decrease in lysis levels. |