Main Title |
Rate of Skin Absorption of Parathion and Paraoxon. |
Author |
Nabb, Dale P. ;
Stein, William J. ;
Hayes., Wayland J. ;
|
CORP Author |
Communicable Disease Center, Atlanta, Ga. |
Year Published |
1965 |
Stock Number |
PB-278 090 |
Additional Subjects |
Absorption(Biology) ;
Pesticides ;
Toxicology ;
Insecticides ;
Permeability ;
Skin(Anatomy) ;
Rates(Per time) ;
Rabbits ;
Laboratory animals ;
Tables(Data) ;
Experimental data ;
Cholinesterase ;
Parenteral infusions ;
Toxicity ;
Bioassay ;
Reprints ;
Parathion ;
Phosphoric acid/(diethyl-ester)-(nitrophenyl-ester) ;
Toxic substances
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB-278 090 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
5p |
Abstract |
The percutaneous absorption rates of parathion and paraoxon have been estimated in rabbits by comparison of the rate of plasma cholinesterase inhibition observed when the compound was infused intravenously with the rate observed when the compound was applied dermally. The average rate of dermal absorption was estimated to be 0.059 micrograms/minute/sq cm of skin area for parathion and 0.32 micrograms/minute/sq cm for paraoxon. Parathion was found to be roughly ten times less toxic intravenously and 55 times less toxic dermally than paraoxon. |