| Main Title |
Selection of adduct-forming chemicals for human monitoring studies / |
| CORP Author |
Environmental Monitoring Systems Lab., Las Vegas, NV. |
| Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Environmental Monitoring Systems Laboratory ; Distributed by the National Technical Information Service, |
| Year Published |
1991 |
| Report Number |
EPA 600-8-91-045; 68-C0-0049 |
| Stock Number |
PB92-132877 |
| OCLC Number |
37399457 |
| Subjects |
Chemicals--Testing ;
Toxicity testing
|
| Additional Subjects |
DNA adducts ;
Toxicity ;
Environmental pollutants ;
Carcinogens ;
Exposure ;
Biological markers ;
Tables(Data) ;
Environmental exposure pathways
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| ELBD ARCHIVE |
EPA 600-8-91-045 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
| NTIS |
PB92-132877 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
vii, 30, [44] pages ; 28 cm |
| Abstract |
The U.S. EPA, through its Environmental Monitoring Systems Laboratory-Las Vegas (EMSL-LV) and its Health Effects Research Laboratory-Research Triangle Park (HERL-RTP) has been exploring the feasibility of using biological markers to monitor exposure to environmental chemicals. The participants began by compiling a list of chemicals of known or suspected health hazards and for which the potential for human exposure exists. The chemicals on the master list were then systematically evaluated for: (1) the potential for adduct-formation in vivo, (2) the availability of supportive adduct research data, (3) the identifiability of exposed population(s), and (4) the level of genetic activity. After considering all the relevant data, the participants selected and prioritized for further study a small group of chemicals considered to have the greatest potential for use in pilot, adduct-based, biological monitoring studies in human populations. |
| Notes |
"EPA 600-8-91-045"--Cover. "May, 1991." "July 1991"--Cover. Contract 68-C0-0049 to Lockheed Engineering and Sciences Company. |
