Record Display for the EPA National Library Catalog

RECORD NUMBER: 26 OF 34

OLS Field Name OLS Field Data
Main Title Rate of Skin Absorption of Parathion and Paraoxon.
Author Nabb, Dale P. ; Stein, William J. ; Hayes., Wayland J. ;
CORP Author Communicable Disease Center, Atlanta, Ga.
Year Published 1965
Stock Number PB-278 090
Additional Subjects Absorption(Biology) ; Pesticides ; Toxicology ; Insecticides ; Permeability ; Skin(Anatomy) ; Rates(Per time) ; Rabbits ; Laboratory animals ; Tables(Data) ; Experimental data ; Cholinesterase ; Parenteral infusions ; Toxicity ; Bioassay ; Reprints ; Parathion ; Phosphoric acid/(diethyl-ester)-(nitrophenyl-ester) ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-278 090 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 5p
Abstract
The percutaneous absorption rates of parathion and paraoxon have been estimated in rabbits by comparison of the rate of plasma cholinesterase inhibition observed when the compound was infused intravenously with the rate observed when the compound was applied dermally. The average rate of dermal absorption was estimated to be 0.059 micrograms/minute/sq cm of skin area for parathion and 0.32 micrograms/minute/sq cm for paraoxon. Parathion was found to be roughly ten times less toxic intravenously and 55 times less toxic dermally than paraoxon.