Record Display for the EPA National Library CatalogRECORD NUMBER: 7 OF 9
|Main Title||Science Advisory Board Review of the Office of Drinking Water (ODW) Issue Paper on Cyanogen Chloride.|
|CORP Author||Environmental Protection Agency, Washington, DC. Drinking Water Committee.|
|Publisher||20 Dec 91|
|Additional Subjects||Drinking water ; Toxicity ; Cyanogen ; Chlorides ; Risk assessment ; Health hazards ; Water treatment ; Biological effects ; Dose-response relationships ; Disinfection ; Chemical reactions ; Pharmacokinetics ; Chemical reactivity ; Environmental health ; Exposure ; Ingestion(Biology) ; Hydrogen cyanide ; Water quality ;|
The Drinking Water Commitee (DWC) of the Science Advisory Board met in Washington, D.C. April 4-5, 1991 to review, among other topics, the Office of Drinking Water issue paper on cyanogen chloride. The DWC was asked to comment on the appropriateness of using hydrogen cyanide (HCN) toxicity data as a surrogate for cyanogen chloride (CICN) data in developing a reference dose (RfD). Cyanogen chloride is a by-product of chloramine disinfection by-product rule. Currently there are no definitive studies of CICN for chronic or subchronic toxicity, mutagenicity, teratogenicity, reproductive or carcinogenic effects. Also, no environmental occurrence data on CICN are available.