Record Display for the EPA National Library Catalog
RECORD NUMBER: 114 OF 335| Main Title | Evaluation of the potential carcinogenicity of dimethylcarbonyl chloride (79-44-7) / | |||||||||||
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| CORP Author | Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. | |||||||||||
| Publisher | U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ; | |||||||||||
| Year Published | 1988 | |||||||||||
| Report Number | EPA/600/8-91/119; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-094 | |||||||||||
| Stock Number | PB93-185361 | |||||||||||
| Subjects | Dimethylcarbonyl--Carcinogenicity | |||||||||||
| Additional Subjects | Carcinogens ; Toxicity ; Humans ; Animals ; Carcinogenicity tests ; Dose-response relationships ; Risk assessment ; Dimethylcarbamoyl chloride ; CAS 79-44-7 | |||||||||||
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| Collation | 20 pages ; 28 cm | |||||||||||
| Abstract | Dimethylcarbamoyl Chloride is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is Inadequate. The potency factor (F) for dimethylcarbamoyl chloride is estimated to be 505 (mg/kg/day), placing it in potency group 1 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, dimethylcarbamoyl chloride is assigned a HIGH hazard ranking for the purposes of RQ adjustment. |
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| Notes | Cover title. "June 1988." Includes bibliographical references. Microfiche. |