Record Display for the EPA National Library Catalog


Main Title Role of Motor Activity in the Asssessment of Neurotoxicity.
Author Stanton, M. E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div.
Publisher 1992
Year Published 1992
Report Number EPA/600/A-92/193;
Stock Number PB92-232818
Additional Subjects Motor activity ; Toxicity ; Nervous system ; Exposure ; Humans ; Behavior ;
Library Call Number Additional Info Location Last
NTIS  PB92-232818 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Motor activity is a behavioral test that has been recommended as a component of testing batteries that evaluate the neurotoxic potential of chemicals. This brief commentary will address the role of this test in such evaluations. It is organized in accordance with the questions that were posed to members of the Work Group on Activity and Observational Data by the conference organizers. For the purposes of this commentary, 'neurotoxicity' is defined as an unwanted effect of an agent on the structure or function of the nervous system. This effect can be direct or indirect, and transient or permanent. in addition, assessment of neurotoxicity occurs in two stages: hazard identification and characterization.