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Main Title Causes of death of anesthesiologists from the chloroform era /
Author Linde, Harry W.,
Other Authors
Author Title of a Work
Mesnick, Paul S.
CORP Author Northwestern Univ., Chicago, IL.;Health Effects Research Lab., Cincinnati, OH.
Publisher Health Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Available to the public through the National Technical Information Service.
Year Published 1979
Report Number EPA-600/1-79-043; EPA-R-805473
Stock Number PB80-125172
OCLC Number 07302207
Subjects Anesthesiologists--United States--Diseases and hygiene ; Nurse anesthetists--United States--Diseases and hygiene ; Chloroform--Physiological effect ; Anesthesiology ; Chloroform--poisoning ; Occupational Diseases--mortality
Additional Subjects Death ; Chloroform ; General anesthetics ; Malignant neoplasms ; Mortality ; Medical personnel ; Chlorine organic compounds ; Chloromethanes ; Carcinogens ; Estimates ; Vapors ; Males ; United States ; Epidemiology ; Heart diseases ; Occupational diseases ; Anesthesiologists ; Cancer ; Death certificates ; Occupational safety and health ; Air pollution effects(Humans)
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD  EPA 600-1-79-043 Headquarters Library/Washington,DC 04/23/2014
ELBD ARCHIVE EPA 600-1-79-043 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
ELBD RPS EPA 600-1-79-043 repository copy AWBERC Library/Cincinnati,OH 10/17/2014
NTIS  PB80-125172 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation ix, 20 pages ; 28 cm.
The investigation was undertaken to determine if there were an excess of cancer deaths occurring in anesthesiologists who practiced in an era when chloroform was in use and to estimate the degree of chloroform usage during that era. Causes of death of anesthesiologists dying between 1930 and 1946 were determined. Death rates in this group of anesthesiologists were compared to rates for U.S. white males, male physicians, anesthesiologists in later decades, and life insurance policyholders. Combined death rates were lower among anesthesiologists than the U.S. male population but exceeded them for some cardiovascular diseases. Death rates for combined malignant neoplasms were low, with digestive organ neoplasms being the most common. Death rates from malignancies of the respiratory tract were unusually low. Anesthesiologists in the United States in the late 19th and early 20th centuries appear to have been occupationally-exposed to chloroform vapor. Their death rates from all malignant neoplasms and from those of the digestive organs are somewhat greater than for anesthesiologists several decades later. No firm conclusions on carcinogenesis can be drawn, however, because of the small population and small number of deaths involved and the different age distributions of the groups of anesthesiologists.
"Northwestern University." "October 1979." Includes bibliographical references. "Grant no. R805473-01."