Record Display for the EPA National Library Catalog


Main Title Scientific basis for the development of the international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds /
Author Safe, S. H. ; Kutz, F. W. ; Bottimore, D. P.
CORP Author NATO Committee on the Challenges of Modern Society, Brussels (Belgium). ;Texas A and M Univ., College Station. ;Versar, Inc., Springfield, VA.;Environmental Protection Agency, Washington, DC.
Publisher Committee on the Challenges of Modern Society,
Year Published 1988
Report Number 68-02-4254; EPA 600-6-90-015; NATO/CCMS-178; EPA-68-02-4245; 600-R-88-104; PB91-109991
Stock Number PB91-109991
OCLC Number 22469929
Subjects Dioxins ; Dioxins--Research ; Dioxins--Law and legislation
Additional Subjects Dioxins ; Toxicity ; Pollution ; Bioassay ; Risk assessment ; Environmental impacts ; Dosage ; Response ; Rats ; Fly ash ; Pyrolysis ; Municipalities ; Concentration(Composition) ; Exposure ; Humans ; EC50 ; Polychlorinated dibenzo p-dioxins ; Dibenzofurans
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  EPA 600-6-90-015 Region 1 Library/Boston,MA 05/25/2016
ELBD ARCHIVE EPA-600-R-88-104 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
ESAD  PB91-109991 Region 10 Library/Seattle,WA 01/27/2006
NTIS  PB91-109991 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation iii, 56 pages.
The Pilot Study on International Information Exchange on Dioxins and Related Compounds was initiated to apply the cooperative efforts of several nations to address issues assoc. with PCDDs, PCDFs, and related compounds. The three-year study was conducted under the aegis of the CCMS of NATO. The report presents a detailed discussion of the scientific basis for the development of toxicity equivalency factors and provides the toxicity data and methodology used to determine the I-TEFs. Section 2 discusses background information on PCDDs and PCDFs. Section 3 discusses the need for I-TEFs. Section 4 presents the mechanisms of toxicity of these compounds. Section 5 provides a discussion of the development of TEFs from experimental toxicity data.
Cover title. "Report of the NATO/CCMS Pilot Study on International Information Exchange on Dioxins and Related Compounds"--Page [i]. "December 1988"--Cover. "Contract No. 68-02-4254"--Page [i]. Includes bibliographical references (pages 46-56).