Record Display for the EPA National Library Catalog


Main Title Role of Short-Term Tests in Evaluating Health Effects Associated with Drinking Water.
Author Meier, J. R. ; Daniel, F. B. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher cOct 90
Year Published 1990
Report Number EPA/600/J-90/326;
Stock Number PB91-149724
Additional Subjects Bioassay ; Toxicity ; Public health ; Water pollution ; Carcinogens ; Genetics ; Potable water ; Risk ; Assessments ; Humans ; Exposure ; Concentration(Composition) ; In vitro analysis ; Rodents ; Comparison ; Time studies ; Cost effectiveness ; Reprints ; Drinking water ; Health assessment ; Ames test
Library Call Number Additional Info Location Last
NTIS  PB91-149724 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Short-term bioassays such as the Ames test are used to assess genotoxicity and potential carcinogenicity of specific drinking water contaminants as well as concentrated samples of drinking water. The authors discuss the development, limitations, and interpretation of short-term tests; qualitative and quantitative aspects of the utility of the tests for predicting carcinogenicity; and general approaches to using the tests in analyzing potential health effects of drinking water. They conclude that although uncertainties regarding interpretation limit the application of such tests for risk assessment, short-term tests provide public health officials with a useful tool for obtaining timely and cost-efficient information about potential health risks associated with drinking water.