Record Display for the EPA National Library Catalog


Main Title Contribution of Woodsmoke and Motor Vehicle Emissions to Ambient Aerosol Mutagenicity (Journal Version).
Author Lewis, C. W. ; Baumgardner, R. E. ; Stevens, R. K. ; Claxton, L. D. ; Lewtas, J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher Aug 88
Year Published 1988
Report Number EPA/600/J-88/237;
Stock Number PB89-142749
Additional Subjects Aerosols ; Exhaust emissions ; Motor vehicles ; Wood ; Mutagens ; Residential buildings ; Bioassays ; Carcinogens ; Fines ; Sources ; Concentration(Composition) ; Trace elements ; Sampling ; Air pollution ; Reprints ; Air pollution effects(Humans)
Library Call Number Additional Info Location Last
NTIS  PB89-142749 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 7p
Mutagenicity is frequently considered as a screening test for the carcinogenicity of compounds to which humans are exposed. Past estimates of the mutagenicity of ambient aerosol have depended on measurements of the mutagenic potency (refertants/microg) of the extractable organic matter (EOM) in Salmonella typhimurium from specific source emissions and their mass emission rate. This source-oriented approach requires an explicit model for the dispersion and possible transformation of the mutagens in the atmosphere. However, a receptor-oriented approach, demonstrated here, requires only ambient measurements of mutagenicity and of trace elements that are markers for the suspected sources of the mutagens. During winter at a residential site, woodsmoke and motor vehicle emissions were found to make nearly equal contributions to the average mutagenic concentration (refertants/cu m) of the fine particle ambient aerosol. Mutagenic potency of the fine particle EOM traced to motor vehicles, however, was three times greater than that with a woodsmoke origin. The results are consistent with the known potency of these sources, from source measurements.