| Main Title |
Approach to Identifying Specialized Batteries of Bioassays for Specific Classes of Chemicals: Class Analysis Using Mutagenicity and Carcinogenicity Relationships and Phylogenetic Concordance and Discordance Patterns. 1. Composition and Analysis of the Overall Data Base. A Report of Phase 2 of the U.S. Environmental Protection Agency Gene-Tox Program. |
| Author |
Ray, V. A. ;
Kier, L. D. ;
Kannan, K. L. ;
Haas, R. T. ;
Auletta, A. E. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Pfizer Central Research, Groton, CT. ;Monsanto Co., St. Louis, MO. ;Oak Ridge National Lab., TN. |
| Year Published |
1987 |
| Report Number |
EPA/600/J-87/296; |
| Stock Number |
PB88-185129 |
| Additional Subjects |
Bioassay ;
Carcinogens ;
Mutagens ;
Chemical analysis ;
Toxicity ;
Data processing ;
Comparison ;
Chemical compounds ;
Testing ;
Reprints ;
Data bases
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB88-185129 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
47p |
| Abstract |
The major utility and/or benefit of this compilation will be derived from a chemical class by chemical class comparative analysis of individual assay performance. The data base will serve as a resource for hazard evaluation of chemicals through structural correlations and biological end points and associated end points such as carcinogenicity. An example analysis is presented using chemical Class 5 (alkyl sulfates sulfoxides, sulfones, sulfonates, organic sulfur compounds not otherwise classified) and includes the four components. (Copyright (c) Elsevier Science Publishers B.V. (Biomedical Division).) |
