Advancing Toxicokinetics for Efficient and Robust Chemical Evaluations

EPA awards five academic research teams to develop New Approach Methods (NAMs) for evaluating chemical toxicokinetics to address gaps in ways to obtain data for informing chemical toxicokinetics and exposure-related factors.

Request for Applications closing date: September 24, 2019

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Identifier Abstract Principal Investigator Institution PROJECT PERIOD Project Start Date Project End Date State
<< STAR GRANTS AND STAR CENTERS >>
1 RD840027
Grant
Integrated blood brain barrier – computational model development to predict doses ofconcern for compound linked neurotoxicity Knipp, Gregory
Stratford, Robert  
Purdue University August 01, 2020 -
July 30, 2023  
August 01, 2020   July 30, 2023   IN  
2 RD840029
Grant
Toxicokinetic screening of zebrafish cytochrome P450 enzymes for in vitro-in vivo extrapolation Goldstone, Jared
Wilson, Joanna  
Woods Hole Oceanographic Institution August 01, 2020 -
July 30, 2023  
August 01, 2020   July 30, 2023   MA  
3 RD840031
Grant
Measuring Toxicokinetics for Organ-on-Chip Devices Hutson, Michael Shane
Markov, Dmitry
McCawley, Lisa J.  
Vanderbilt University August 01, 2020 -
July 30, 2023  
August 01, 2020   July 30, 2023   TN  
4 RD840032
Grant
Integrating tissue chips, rapid untargeted analytical methods and molecular modeling for toxicokinetic screening of chemicals, their metabolites and mixtures Rusyn, Ivan
Baker, Erin D.
Chiu, Weihsueh A  
Texas A&M University, North Carolina State University August 01, 2020 -
July 30, 2023  
August 01, 2020   July 30, 2023   TX  
5 RD840033
Grant
An in vitro-in silico hybrid approach for high-throughput estimation of trans-barrier permeability for chemical pollutants Li, Dingsheng
Bell, Thomas W
Li, Li
Earley, Yumei F  
University of Nevada - Reno August 01, 2020 -
July 30, 2023  
August 01, 2020   July 30, 2023   NV  



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