Grantee Research Project Results
Selected Publications Details for Grant Number R830800
Reducing Uncertainty in Children’s Risk Assessment: Development of a Quantitative Approach for Assessing Internal Dosimetry Through Physiologically-Based Pharmacokinetic Modeling
RFA:
Children's Vulnerability to Toxic Substances in the Environment (2002)
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Journal Article | Anand SS, Bruckner JV, Haines WT, Muralidhara S, Fisher JW, Padilla S. Characterization of deltamethrin metabolism by rat plasma and liver microsomes. Toxicology and Applied Pharmacology 2006;212(2):156-166. |
R830800 (2005) R830800 (2006) R830800 (Final) |
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| Journal Article | Anand SS, Kim K-B, Padilla S, Muralidhara S, Kim HJ, Fisher JW, Bruckner JV. Ontogeny of hepatic and plasma metabolism of deltamethrin in vitro: role in age-dependent acute neurotoxicity. Drug Metabolism and Disposition 2006;34(3):389-397. |
R830800 (2005) R830800 (2006) R830800 (Final) |
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| Journal Article | Ding Y, White CA, Muralidhara S, Bruckner JV, Bartlett MG. Determination of deltamethrin and its metabolite 3-phenoxybenzoic acid in male rat plasma by high-performance liquid chromatography. Journal of Chromatography B 2004;810(2):221-227. |
R830800 (2003) R830800 (2004) R830800 (2005) R830800 (2006) R830800 (Final) R830900 (2004) |
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| Journal Article | Ding Y, White CA, Bruckner JV, Bartlett MG. Determination of deltamethrin and its metabolites, 3-phenoxybenzoic acid and 3-phenoxybenzyl alcohol, in maternal plasma, amniotic fluid, and placental and fetal tissues by HPLC. Journal of Liquid Chromatography & Related Technologies 2004;27(12):1875-1892. |
R830800 (2003) R830800 (2004) R830800 (2005) R830800 (2006) R830800 (Final) R830900 (2004) |
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| Journal Article | Kim KB, Bartlett MG, Anand SS, Bruckner JV, Kim HJ. Rapid determination of the synthetic pyrethroid insecticide, deltamethrin, in rat plasma and tissues by HPLC. Journal of Chromatography B 2006;834(1-2):141-148. |
R830800 (2005) R830800 (2006) R830800 (Final) |
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| Journal Article | Kim K-B, Anand SS, Muralidhara S, Kim HJ, Bruckner JV. Formulation-dependent toxicokinetics explains differences in the GI absorption, bioavailability and acute neurotoxicity of deltamethrin in rats. Toxicology 2007;234(3):194-202. |
R830800 (2006) R830800 (Final) |
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| Journal Article | Kim K-B, Anand SS, Kim HJ, White CA, Bruckner JV. Toxicokinetics and tissue distribution study of deltamethrin in adult Sprague-Dawley rats. Toxicological Sciences 2008;101(2):197-205. |
R830800 (Final) |
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| Journal Article | Kim K-B, Anand SS, Kim HJ, White CA, Fisher JW, Tornero-Velez R, Bruckner JV. Age, dose, and time-dependency of plasma and tissue distribution of deltamethrin in immature rats. Toxicological Sciences 2010;115(2):354-368. |
R830800 (Final) |
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| Journal Article | Mirfazaelian A, Kim K-B, Anand SS, Kim HJ, Tornero-Velez R, Bruckner JV, Fisher JW. Development of a physiologically based pharmacokinetic model for deltamethrin in the adult male Sprague-Dawley rat. Toxicological Sciences 2006;93(2):432-442. |
R830800 (2005) R830800 (2006) R830800 (Final) R840032 (2023) |
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| Journal Article | Mirfazaelian A, Fisher JW. Organ growth functions in maturing male Sprague-Dawley rats based on a collective database. Journal of Toxicology and Environmental Health Part A 2007;70(12):1052-1063. |
R830800 (2005) R830800 (Final) |
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| Journal Article | Mirfazaelian A, Kim K-B, Lee S, Kim HJ, Bruckner JV, Fisher JW. Organ growth functions in maturing male Sprague-Dawley rats. Journal of Toxicology and Environmental Health-Part A 2007;70(5):429-438. |
R830800 (2006) R830800 (Final) |
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| Journal Article | Tornero-Velez R, Mirfazaelian A, Kim K-B, Anand SS, Kim HJ, Haines WT, Bruckner JV, Fisher JW. Evaluation of deltamethrin kinetics and dosimetry in the maturing rat using a PBPK model. Toxicology and Applied Pharmacology 2010;244(2):208-217. |
R830800 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.