Grantee Research Project Results
Publications Details for Grant Number R833320
A Rapid In Vivo System for Determining Toxicity of Manufactured Nanomaterials
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Reference Type | Citation | Progress Report Year | Document Sources |
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Journal Article | Harper SL, Dahl JA, Maddux BLS, Tanguay RL, Hutchison JE. Proactively designing nanomaterials to enhance performance and minimise hazard. International Journal of Nanotechnology 2008;5(1):124-142. |
R833320 (2008) R833320 (Final) |
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Journal Article | Harper SL, Carriere JL, Miller JM, Hutchison JE, Maddux BLS, Tanguay RL. Systematic evaluation of nanomaterial toxicity: utility of standardized materials and rapid assays. ACS Nano 2011;5(6):4688-4697. |
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Journal Article | Harper S, Usenko C, Hutchison JE, Maddux BLS, Tanguay RL. In vivo biodistribution and toxicity depends on nanomaterial composition, size, surface functionalisation and route of exposure. Journal of Experimental Nanoscience 2008;3(3):195-206. |
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Journal Article | Isaacson CW, Usenko CY, Tanguay RL, Field JA. Quantification of fullerenes by LC/ESI-MS and its application to in vivo toxicity assays. Analytical Chemistry 2007;79(23):9091-9097. |
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Journal Article | Thomas DG, Klaessig F, Harper SL, Fritts M, Hoover MD, Gaheen S, Stokes TH, Reznik-Zellen R, Freund ET, Klemm JD, Paik DS, Baker NA. Informatics and standards for nanomedicine technology. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 2011;3(5):511-532. |
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Journal Article | Truong L, Moody IS, Stankus DP, Nason JA, Lonergan MC, Tanguay RL. Differential stability of lead sulfide nanoparticles influences biological responses in embryonic zebrafish. Archives of Toxicology 2011;85(7):787-798. |
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Journal Article | Truong L, Harper SL, Tanguay RL. Evaluation of embryotoxicity using the zebrafish model. Methods in Molecular Biology 2011;691(Part 6):271-279. |
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Journal Article | Truong L, Zaikova T, Richman EK, Hutchison JE, Tanguay RL. Media ionic strength impacts embryonic responses to engineered nanoparticle exposure. Nanotoxicology 2012;6(7):691-699. |
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Journal Article | Truong L, Saili KS, Miller JM, Hutchison JE, Tanguay RL. Persistent adult zebrafish behavioral deficits results from acute embryonic exposure to gold nanoparticles. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2012;155(2):269-274. |
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Journal Article | Truong L, Tilton SC, Zaikova T, Richman E, Waters KM, Hutchison JE, Tanguay RL. Surface functionalities of gold nanoparticles impact embryonic gene expression responses. Nanotoxicology 2013;7(2):192-201. |
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Journal Article | Usenko CY, Harper SL, Tanguay RL. In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish. Carbon 2007;45(9):1891-1898. |
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Journal Article | Usenko CY, Harper SL, Tanguay RL. Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish. Toxicology and Applied Pharmacology 2008;229(1):44-55. |
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Presentation | Duong L, Harper S, Saili K, Tanguay R. A rapid in vivo platform for evaluating nanomaterial-biological interactions. Poster presented to the U.S. Army Research Laboratory (ARL), Corvallis, OR, February 1, 2008. |
R833320 (Final) |
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Presentation | Harper SL, Tanguay RL. Development of a nanomaterials effects database using a mass collaborative approach. Presented at Safer Nano 2007, Eugene, OR, March 12-13, 2007. |
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Presentation | Harper SL, Tanguay RL, Hutchison JE. In vivo toxicity evaluations of gold nanoparticles: proactively designing safer nanomaterials. Presented at the Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 25-29, 2007. |
R833320 (2008) R833320 (Final) |
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Presentation | Harper SL, Lee S, Tanguay RL. An integrative knowledgebase of nanomaterial-biological interactions. Presented at the Pacific Northwest Association of Toxicologists Annual Meeting, University of Washington School of Public Health, Seattle, WA, September 14-15, 2007. |
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Presentation | Harper SL. Integrative approaches to greener nanotechnology. Presented at the North American Hazardous Materials Management Association Conference for Household and Small Business Programs, Troutdale, OR, June 9-12, 2008. |
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Presentation | Harper SL, Lee S, Tanguay RL. An EZ metric for evaluating nanomaterial-biological interactions. Presented at the Society of Toxicology 47th Annual Meeting, Seattle, WA, March 16-20, 2008. |
R833320 (2008) R833320 (Final) |
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Presentation | Harper S, Saili K, Duong L, Lee S, Tanguay R. Integrative research strategies to evaluate environmental health and safety of nanomaterials. Presented at the Pacific Northwest Society of Toxicology Meeting, Corvallis, OR, September 18-19, 2008. |
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Presentation | Heredia-Langner A, Lins RD, Tanguay RL, Harper SL, Hutchison J, Teeguarden JG, Pounds JG, Webb-Robertson B-J, Thrall BD. Poster presentation (no title). Poster presented at the 48th Annual Society of Toxicology Meeting, Baltimore, MD, March 15-19, 2009. |
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Presentation | Maddux BLS, Harper SL, Tanguay RL, Hutchison JE. Developing proactive design strategies in nanoscience to reduce uncertainty and enhance performance and minimize hazard. Presented at the 12th Annual Green Chemistry and Engineering Conference, Environmental Decision Making and Metrics, Washington, DC, June 24-26, 2008. |
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Presentation | Park S, Bermardi B, Wang Y, Maloney T, Harper SL, Lee S, Tanguay RL. The nanomaterial-biological interactions knowledgebase. Presented at the 3rd Annual Greener Nanoscience Conference & Program Review, Corvallis, OR, March 10-11, 2008. |
R833320 (2008) |
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Presentation | Saili K, Truong L, Harper S, Vercruysse K, Tanguay R. Gold and silver nanomaterials exhibit anti-inflammatory properties in vivo. Poster presented at the Greener Nano Conference, Eugene, OR, March 2-3, 2009. |
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Presentation | Tanguay RL, Usenko CY, Harper SL. In vivo nanomaterial-biological interactions: defining structure response relationships. Presented at the 235th American Chemical Society National Meeting, New Orleans, LA, April 6-10, 2008. |
R833320 (2008) R833320 (Final) |
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Presentation | Tanguay RL. Proactively defining in vivo nanomaterial biological interactions to guide development of greener nanomaterials. Presented at the Gordon Conference on Green Chemistry, Bates College, Lewiston, ME, August 3-8, 2008. |
R833320 (2008) |
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Presentation | Tanguay RL, Mathew LK, Harper SL. Unraveling environmental biological interactions using zebrafish. Presented at the Society of Toxicology 47th Annual Meeting, Seattle, WA, March 16-20, 2008. |
R833320 (2008) R833320 (Final) |
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Presentation | Tanguay RL. Safer nanomaterial design guided by rapid throughput assessment of in vivo nanomaterial/biological responses. Presented at the IMNI Nanoscience Forum, Brown University, May 5-7, 2008. |
R833320 (2008) |
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Presentation | Tanguay R, Truong L, Usenko C, Harper S, Hutchison J. Optimizing in vivo assessment of nano/bio interactions. Presented at the U.S. Environmental Protection Agency Nanotechnology Grantee Meeting, Las Vegas, NV, November 9, 2009. |
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Presentation | Tanguay R, Truong L. Optimizing in vivo assessment of nano/bio interactions to guide safer material design. Presented at the Materials Research Society Fall Meeting, Boston, MA, November 29, 2010. |
R833320 (Final) |
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Presentation | Truong L, Harper S, Tanguay R. An in vivo assessment of zinc oxide nanoparticles (ZnO NP) using the embryonic zebrafish. Presented at the Pacific Northwest Society of Toxicology Meeting, Corvallis, OR, September 18-19, 2008. |
R833320 (Final) |
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Presentation | Truong L, Harper S, Miller J, Hutchison J, Tanguay R. Gold nanoparticle (AuNP) surface charge influences toxicity. Poster presented at the Society of Toxicology 48th Annual Meeting, Baltimore, MD, March 15-19, 2009. |
R833320 (Final) |
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Presentation | Truong L, Harper S, Miller J, Hutchison J, Tanguay R. Surface charges on gold nanoparticles (AuNP) influences biological responses. Poster presented at the Greener Nano Conference, Eugene, OR, March 2-3, 2009. |
R833320 (Final) |
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Presentation | Truong L, Harper S, Miller J, Hutchison J, Tanguay R. Surface charge on gold nanoparticles (AuNPs) influences toxicity in embryonic zebrafish. Presented at the Pacific Northwest Society of Toxicology Meeting, Seattle, WA, September 17-18, 2009. |
R833320 (Final) |
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Presentation | Truong L, Miller J, Hutchison J, Tanguay R. The surface functionality of gold nanoparticles impacts embryonic gene expression responses. Poster presented at the Oregon State University Environmental and Molecular Toxicology Research Day, Corvallis, OR, January 29, 2010. |
R833320 (Final) |
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Presentation | Truong L, Zaikova T, Richman E, Miller J, Harper S, Hutchison J, Tanguay R. Integrative strategy to develop greener nanotechnology. Poster presented at the Greener Nano Conference, Portland, OR, June 16-18, 2010. |
R833320 (Final) |
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Presentation | Truong L, Miller J, Hutchison J, Tanguay R. The surface functionality of gold nanoparticles impacts embryonic gene expression responses. Poster presented at the Society of Toxicology 49th Annual Meeting, Salt Lake City, UT, March 7-11, 2010. |
R833320 (Final) |
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Presentation | Truong L, Neigh A, Tanguay R. Silver nanoparticles induce size-independent biological responses in embryonic zebrafish. Poster presented at the Society of Environmental Toxicology and Chemistry Meeting, Portland, OR, November 8-11, 2010. |
R833320 (Final) |
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Presentation | Truong L, Zaikova T, Hutchison J, Tanguay R. Refining parameters to improve the zebrafish model for nanomaterial-biological interaction assessments. Presented at the U.S. Environmental Protection Agency Nanotechnology Grantee Meeting, Portland, OR, November 9, 2010. |
R833320 (Final) |
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Presentation | Truong L, Zaikova T, Richman E, Miller J, Harper S, Hutchison J, Tanguay R. Gold nanoparticles: surface charge and functionality impacts embryonic gene expression responses. Poster presented at the Aquatic Animal Models for Human Disease Conference, Corvallis, OR, September 20-22, 2010. |
R833320 (Final) |
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Presentation | Vercruysse KP, Harper SL, Ivory DM, Whalen MM, Saili KS, Tanguay RL. Potential anti-inflammatory properties of biologically-synthesized nanoparticles of gold or silver. Presented at the Nano Science and Technology Institute Nanotech Conference, June 1-5, 2008. |
R833320 (2008) R833320 (Final) |
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Proceedings | Vercruysse KP, Harper SL, Ivory DM, Whalen MM, Saili KS, Tanguay RL. Potential anti-inflammatory properties of biologically-synthesized nanoparticles of gold or silver. In: Nanotechnology 2008: Life Sciences, Medicine & Bio Materials-Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 2. Danville, CA: Nano Science and Technology Institute, pp. 501-504. |
R833320 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.