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Book Chapter (1)
Journal Article (43)
Presentation (58)
Proceedings (10)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Abstract Quantitative structure toxicity relationships (QSTR) models for predicting acute/sub-acute and sub-chronic/chronic adverse effect levels. None Easterling M, Tropsha A, Ye L, Pirone J, Zhu H, Martin T, Moudgal C Easterling M, Tropsha A, Ye L, Pirone J, Zhu H, Martin T, Moudgal C. Quantitative structure toxicity relationships (QSTR) models for predicting acute/sub-acute and sub-chronic/chronic adverse effect levels. The Toxicologist 2009;108(1):234. R832720 (2009)
Abstract Cheminformatics analysis of EPA ToxCast chemical libraries to identify domains of applicability for predictive toxicity models and prioritize compounds for toxicity testing. None Zhang L, Zhu H, Rusyn I, Judson R, Dix D, Houck K, Martin M, Richard A, Kavlock R, Tropsha A Zhang L, Zhu H, Rusyn I, Judson R, Dix D, Houck K, Martin M, Richard A, Kavlock R, Tropsha A. Cheminformatics analysis of EPA ToxCast chemical libraries to identify domains of applicability for predictive toxicity models and prioritize compounds for toxicity testing. The Toxicologist 2009;108(1):226. R832720 (2009)
Abstract Combinatorial QSAR modeling of rat acute toxicity by oral exposure. None Zhu H, Martin TM, Ye L, Young DM, Tropsha A Zhu H, Martin TM, Ye L, Young DM, Tropsha A. Combinatorial QSAR modeling of rat acute toxicity by oral exposure. The Toxicologist 2009;108(1):234. R832720 (2009)
Book Chapter Supporting Computational Systems Science:Genomic Analysis Tool Federations Using Aspects and AOP. None Stotts D, Lee K, Rusyn I Stotts D, Lee K, Rusyn I. Supporting computational systems science: genomic analysis tool federations using aspects and AOP. In: Mandoiu I, Sunderraman R, Zelikovsky A, eds. Bioinformatics Research and Applications. Proceedings of the Fourth International Symposium ISBRA 2008. Berlin/Heidelberg, Germany: Springer Berlin/Heidelberg, 2008, pp. 457-468. R832720 (2008)
Journal Article Activity prediction and identification of mis-annotated chemical compounds using extreme descriptors. JOURNAL OF CHEMOMETRICS Borysov P, Hannig J, Marron JS, Muratov E, Fourches D, Tropsha A Borysov P, Hannig J, Marron JS, Muratov E, Fourches D, Tropsha A. Activity prediction and identification of mis-annotated chemical compounds using extreme descriptors. Journal of Chemometrics 2016;30(3):99-108. R832720 (2009)
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Journal Article Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease. None Bradford BU, O'Connell TM, Han J, Kosyk O, Shymonyak S, Ross PK, Winnike J, Kono H, Rusyn I Bradford BU, O'Connell TM, Han J, Kosyk O, Shymonyak S, Ross PK, Winnike J, Kono H, Rusyn I. Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease. Toxicology and Applied Pharmacology 2008;232(2):236-243. R832720 (2008)
Journal Article A new class of mixture models for differential gene expression in DNA microarray data. JOURNAL OF STATISTICAL PLANNING AND INFERENCE Chen M-H, Ibrahim JG, Chi Y-Y Chen M-H, Ibrahim JG, Chi Y-Y. A new class of mixture models for differential gene expression in DNA microarray data. Journal of Statistical Planning and Inference 2008;138(2):387-404. R832720 (2006)
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Journal Article Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. CHEMICAL RESEARCH TOXICOLOGY Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ , Tropsha A Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical Research in Toxicology 2010;23(1):171-183. R832720 (2009)
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Journal Article Trust, but verify: on the importance of chemical structure curation in cheminformatics and QSAR modeling research. JOURNAL OF CHEMICAL INFORMATION AND MODELING Fourches D, Muratov E, Tropsha A Fourches D, Muratov E, Tropsha A. Trust, but verify: on the importance of chemical structure curation in cheminformatics and QSAR modeling research. Journal of Chemical Information and Modeling 2010;50(7):1189-1204. R832720 (2009)
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Journal Article Predicting binding affinity of CSAR ligands using both structure-based and ligand-based approaches. JOURNAL OF CHEMICAL INFORMATION AND MODELING Fourches D, Muratov E, Ding F, Dokholyan NV, Tropsha A Fourches D, Muratov E, Ding F, Dokholyan NV, Tropsha A. Predicting binding affinity of CSAR ligands using both structure-based and ligand-based approaches. Journal of Chemical Information and Modeling 2013;53(8):1915-1922. R832720 (2009)
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Journal Article FastMap: fast eQTL mapping in homozygous populations. None Gatti DM, Shabalin AA, Lam T-C, Wright FA, Rusyn I, Nobel AB Gatti DM, Shabalin AA, Lam T-C, Wright FA, Rusyn I, Nobel AB. FastMap: fast eQTL mapping in homozygous populations. Bioinformatics 2009;25(4):482-489. R832720 (2008)
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Journal Article SAFEGUI: resampling-based tests of categorical significance in gene expression data made easy. None Gatti DM, Sypa M, Rusyn I, Wright FA, Barry WT Gatti DM, Sypa M, Rusyn I, Wright FA, Barry WT. SAFEGUI: resampling-based tests of categorical significance in gene expression data made easy. Bioinformatics 2009;25(4):541-542. R832720 (2008)
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Journal Article Replication and narrowing of gene expression quantitative trait loci using inbred mice. MAMMALIAN GENOME Gatti DM, Harrill AH, Wright FA, Threadgill DW, Rusyn I Gatti DM, Harrill AH, Wright FA, Threadgill DW, Rusyn I. Replication and narrowing of gene expression quantitative trait loci using inbred mice. Mammalian Genome 2009;20(7):437-446. R832720 (2009)
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Journal Article Genome-level analysis of genetic regulation of liver gene expression networks. HEPATOLOGY Gatti D, Maki A, Chesler EJ, Kirova R, Kosyk O, Lu L, Manly KF, Williams RW, Perkins A, Langston MA, Threadgill DW, Rusyn I Gatti D, Maki A, Chesler EJ, Kirova R, Kosyk O, Lu L, Manly KF, Williams RW, Perkins A, Langston MA, Threadgill DW, Rusyn I. Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology 2007;46(2):548-557. R832720 (2007)
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Journal Article Proximity model for expression quantitative trait loci (eQTL) detection. BIOMETRICS Gelfond JAL, Ibrahim JG, Zou F Gelfond JAL, Ibrahim JG, Zou F. Proximity model for expression quantitative trait loci (eQTL) detection. Biometrics 2007;63(4):1108-1116. R832720 (2006)
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Journal Article Estimating odds ratios in genome scans:an approximate conditional likelihood approach. None Ghosh A, Zou F, Wright FA Ghosh A, Zou F, Wright FA. Estimating odds ratios in genome scans: an approximate conditional likelihood approach. The American Journal of Human Genetics 2008;82(5):1064-1074. R832720 (2008)
Journal Article Analysis of the transcriptome of Group A Streptococcus in mouse soft tissue infection. AMERICAN JOURNAL OF PATHOLOGY Graham MR, Virtaneva K, Porcella SF, Gardner DJ, Long RD, Welty DM, Barry WT, Johnson CA, Parkins LD, Wright FA, Musser JM Graham MR, Virtaneva K, Porcella SF, Gardner DJ, Long RD, Welty DM, Barry WT, Johnson CA, Parkins LD, Wright FA, Musser JM. Analysis of the transcriptome of Group A Streptococcus in mouse soft tissue infection. American Journal of Pathology 2006;169(3):927-942. R832720 (2007)
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Journal Article Variable selection in regression mixture modeling for the discovery of gene regulatory networks. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION Gupta M, Ibrahim JG Gupta M, Ibrahim JG. Variable selection in regression mixture modeling for the discovery of gene regulatory networks. Journal of the American Statistical Association 2007;102(479):867-880. R832720 (2006)
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Journal Article Generalized hierarchical Markov models for the discovery of length-constrained sequence features from genome tiling arrays. BIOMETRICS Gupta M Gupta M. Generalized hierarchical Markov models for the discovery of length-constrained sequence features from genome tiling arrays. Biometrics 2007;63(3):797-805. R832720 (2006)
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Journal Article Towards high throughput metabolomics using ultrahigh field Fourier transform ion cyclotron resonance mass spectrometry. None Han J, Danell RM, Patel JR, Gumerov DR, Scarlett CO, Speir JP, Parker CE, Rusyn I, Zeisel S, Borchers CH Towards high throughput metabolomics using ultrahigh field Fourier transform ion cyclotron resonance mass spectrometry Han J, Danell RM, Patel JR, Gumerov DR, Scarlett CO, Speir JP, Parker CE, Rusyn I, Zeisel S, Borchers CH. Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry. Metabolomics 2008;4(2):128-140. R832720 (2008)
Journal Article Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity. None Harrill AH, Rusyn I Harrill AH, Rusyn I. Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity. Expert Opinion on Drug Metabolism & Toxicology 2008;4(11):1379-1389. R832720 (2008)
Journal Article Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. TOXICOLOGICAL SCIENCES Harrill AH, Ross PK, Gatti DM, Threadgill DW, Rusyn I Harrill AH, Ross PK, Gatti DM, Threadgill DW, Rusyn I. Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel. Toxicological Sciences 2009;110(1):235-243. R832720 (2009)
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Journal Article Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. GENOME RESEARCH Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA, Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris C, Contractor T, Wiltshire T, Rusyn I, Threadgill DW Harrill AH, Watkins PB, Su S, Ross PK, Harbourt DE, Stylianou IM, Boorman GA, Russo MW, Sackler RS, Harris SC, Smith PC, Tennant R, Bogue M, Paigen K, Harris C, Contractor T, Wiltshire T, Rusyn I, Threadgill DW. Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans. Genome Research 2009;19(9):1507-1515. R832720 (2009)
Journal Article Transcriptional response of rat frontal cortex following acute in vivo exposure to the pyrethroid insecticides permethrin and deltamethrin. None Harrill JA ,Li Z, Wright FA, Radio NM, Mundy WR, Tornero-Velez R, Crofton KM Harrill JA ,Li Z, Wright FA, Radio NM, Mundy WR, Tornero-Velez R, Crofton KM. Transcriptional response of rat frontal cortex following acute in vivo exposure to the pyrethroid insecticides permethrin and deltamethrin. BMC Genomics 2008;9:546. R832720 (2008)
Journal Article Estimation of expression indexes for oligonucleotide arrays using the singular value decomposition. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION Hu J, Wright FA, Zou F Hu J, Wright FA, Zou F. Estimation of expression indexes for oligonucleotide arrays using the singular value decomposition. Journal of the American Statistical Association 2006;101(473):41-50. R832720 (2006)
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Journal Article Assessing differential gene expression with small sample sizes in oligonucleotide arrays using a mean-variance model. BIOMETRICS Hu J, Wright FA Hu J, Wright FA. Assessing differential gene expression with small sample sizes in oligonucleotide arrays using a mean-variance model. Biometrics 2007;63(1):41-49. R832720 (2006)
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Journal Article A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scaledData model. None Judson R, Elloumi F, Setzer WR, Li Z , Shah I Judson R, Elloumi F, Setzer RW, Li Z , Shah I. A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model. BMC Bioinformatics 2008;9:241-256. R832720 (2008)
Journal Article Age-dependent variability in gene expression in male Fischer 344 rat retina. None Li Z, Wright FA, Royland J Li Z, Wright FA, Royland J. Age-dependent variability in gene expression in male Fischer 344 rat retina. Toxicological Sciences 2009;107(1):281-292. R832720 (2008)
Journal Article Statistical Significance of Clustering for High-Dimension, Low–Sample Size Data JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION Liu Y, Hayes D, Nobel A, Marron J Liu Y, Hayes D, Nobel A, Marron J. Statistical Significance of Clustering for High-Dimension, Low–Sample Size Data. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION 2012;103(483):1281-1293. R832720 (2009)
Journal Article Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays. None Low YS, Sedykh AY, Rusyn I, Tropsha A Low YS, Sedykh AY, Rusyn I, Tropsha A. Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays. Current Topics in Medicinal Chemistry 2014;14(11):1356-1364. R832720 (2009)
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Journal Article QSAR analysis of (biphenyloxy)propyl isoxazoles: agents against coxsackievirus B3. FUTURE MEDICINAL CHEMISTRY Muratov EN, Varlamova EV, Artemenko AG, Khristova T, Kuz'min VE, Makarov VA, Riabova OB, Wutzler P, Schmidtke M Muratov EN, Varlamova EV, Artemenko AG, Khristova T, Kuz'min VE, Makarov VA, Riabova OB, Wutzler P, Schmidtke M. QSAR analysis of [(biphenyloxy)propyl] isoxazoles: agents against coxsackievirus B3. Future Medicinal Chemistry 2011;3(1):15-27. R832720 (2009)
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Journal Article Existing and developing approaches for QSAR analysis of mixtures. MOLECULAR INFORMATICS Muratov EN, Varlamova EV, Artemenko AG, Polishchuk PG, Kuz'min VE Muratov EN, Varlamova EV, Artemenko AG, Polishchuk PG, Kuz'min VE. Existing and developing approaches for QSAR analysis of mixtures. Molecular Informatics 2012;31(3-4):202-221. R832720 (2009)
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Journal Article QSAR analysis of poliovirus inhibition by dual combinations of antivirals. STRUCTURAL CHEMISTRY Muratov EN, Varlamova EV, Artemenko AG, Polishchuk PG, Nikolaeva-Glomb L, Galabov AS, Kuz'min VE Muratov EN, Varlamova EV, Artemenko AG, Polishchuk PG, Nikolaeva-Glomb L, Galabov AS, Kuz'min VE. QSAR analysis of poliovirus inhibition by dual combinations of antivirals. Structural Chemistry 2013;24(5):1665-1679. R832720 (2009)
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Journal Article Large-scale gene expression differences across brain regions and inbred strains correlates with a behavioral phenotype. GENETICS Nadler JJ, Zou F, Huang H, Moy SS, Lauder J, Crawley JN, Threadgill DW, Wright FA, Magnuson TR Nadler JJ, Zou F, Huang H, Moy SS, Lauder J, Crawley JN, Threadgill DW, Wright FA, Magnuson TR. Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype. Genetics 2006;174(3):1229-1236. R832720 (2006)
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Journal Article Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet. JOURNAL OF HEPATOLOGY Pogribny IP, Tryndyak VP, Bagnyukova TV, Melnyk S, Montgomery B, Ross SA, Latendresse JR, Rusyn I, Beland FA Pogribny IP, Tryndyak VP, Bagnyukova TV, Melnyk S, Montgomery B, Ross SA, Latendresse JR, Rusyn I, Beland FA. Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet. Journal of Hepatology 2009;51(1):176-186. R832720 (2009)
Journal Article Universal approach for structural interpretation of QSAR/QSPR models. MOLECULAR INFORMATICS Polishchuk PG, Kuz'min VE, Artemenko AG, Muratov EN Polishchuk PG, Kuz'min VE, Artemenko AG, Muratov EN. Universal approach for structural interpretation of QSAR/QSPR models. Molecular Informatics 2013;32(9-10):843-853. R832720 (2009)
Journal Article The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics. MAMMALIAN GENOME Roberts A, Pardo-Manuel de Villena F, Wang W, McMillan L, Threadgill DW Roberts A, Pardo-Manuel de Villena F, Wang W, McMillan L, Threadgill DW. The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics. Mammalian Genome 2007;18(6-7):473-481. R832720 (2007)
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Journal Article A Bayesian Model for Cross-Study Differential Gene Expression JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION Scharph R, Tjelmeland H, Parmigiani G, Nobel A Scharph R, Tjelmeland H, Parmigiani G, Nobel A. A Bayesian Model for Cross-Study Differential Gene Expression. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION 2012;104(488):1295-1310 R832720 (2009)
Journal Article Critical Assessment of QSAR Models of Environmental Toxicity against Tetrahymena pyriformis:Focusing on Applicability Domain and Overfitting by Variable Selection. None Tetko IV, Sushko I, Pandey AK, Zhu H, Tropsha A, Papa E, Öberg T, Todeschini R, Fourches D, Varnek A Tetko IV, Sushko I, Pandey AK, Zhu H, Tropsha A, Papa E, Oberg T, Todeschini R, Fourches D, Varnek A. Critical assessment of QSAR models of environmental toxicity against Tetrahymena pyriformis: focusing on applicability domain and overfitting by variable selection. Journal of Chemical Information and Modeling 2008;48(9):1733-1746. R832720 (2008)
Journal Article Predictive QSAR modeling workflow, model applicability domains, and virtual screening. CURRENT PHARMACEUTICAL DESIGN Tropsha A, Golbraikh A Tropsha A, Golbraikh A. Predictive QSAR modeling workflow, model applicability domains, and virtual screening. Current Pharmaceutical Design 2007;13(34):3494-3504. R832720 (2007)
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Journal Article Time course investigation of PPARα- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression. TOXICOLOGY AND APPLIED PHARMACOLOGY Woods CG, Kosyk O, Bradford BU, Ross PK, Burns AM, Cunningham ML, Qu P, Ibrahim JG, Rusyn I Woods CG, Kosyk O, Bradford BU, Ross PK, Burns AM, Cunningham ML, Qu P, Ibrahim JG, Rusyn I. Time course investigation of PPARα- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression. Toxicology and Applied Pharmacology 2007;225(3):267-277. R832720 (2007)
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Journal Article Genomic profiling in nuclear receptor-mediated toxicity. TOXICOLOGIC PATHOLOGY Woods CG, Vanden Heuvel JP, Rusyn I Woods CG, Vanden Heuvel JP, Rusyn I. Genomic profiling in nuclear receptor-mediated toxicity. Toxicologic Pathology 2007;35(4):474-494. R832720 (2007)
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Journal Article Simulating association studies: a data-based resampling method for candidate regions or whole genome scans. BIOINFORMATICS Wright FA, Huang H, Guan X, Gamiel K, Jeffries C, Barry WT, Pardo-Manuel de Villena F, Sullivan PF, Wilhelmsen KC, Zou F Wright FA, Huang H, Guan X, Gamiel K, Jeffries C, Barry WT, Pardo-Manuel de Villena F, Sullivan PF, Wilhelmsen KC, Zou F. Simulating association studies: a data-based resampling method for candidate regions or whole genome scans. Bioinformatics 2007;23(19):2581-2588. R832720 (2007)
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Journal Article Combinatorial QSAR Modeling of Chemical Toxicants Tested against Tetrahymena pyriformis. None Zhu H, Tropsha A, Fourches D, Varnek A, Papa E, Gramatica P, Oberg T, Dao P, Cherkasov A, Tetko I V Zhu H, Tropsha A, Fourches D, Varnek A, Papa E, Gramatica P, Oberg T, Dao P, Cherkasov A, Tetko IV. Combinatorial QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. Journal of Chemical Information and Modeling 2008;48(4):766-784. R832720 (2008)
Journal Article Use of cell viability assay data improves the prediction accuracy of conventional quantitative structure-activity relationship models of animal carcinogenicity. None Zhu H, Rusyn I, Richard A, Tropsha A Zhu H, Rusyn I, Richard A, Tropsha A. Use of cell viability assay data improves the prediction accuracy of conventional quantitative structure-activity relationship models of animal carcinogenicity. Environmental Health Perspectives 2008;116(4):506-513. R832720 (2007)
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Journal Article A novel two-step hierarchical quantitative structure-activity relationship modeling work flow for predicting acute toxicity of chemicals in rodents. ENVIRONMENTAL HEALTH PERSPECTIVES Zhu H, Ye L, Richard A, Golbraikh A, Wright FA, Rusyn I, Tropsha A Zhu H, Ye L, Richard A, Golbraikh A, Wright FA, Rusyn I, Tropsha A. A novel two-step hierarchical quantitative structure-activity relationship modeling work flow for predicting acute toxicity of chemicals in rodents. Environmental Health Perspectives 2009;117(8):1257-1264. R832720 (2009)
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Journal Article Quantitative structure-activity relationship modeling of rat acute toxicity by oral exposure. CHEMICAL RESEARCH TOXICOLOGY Zhu H, Martin TM, Ye L, Sedykh A, Young DM, Tropsha A Zhu H, Martin TM, Ye L, Sedykh A, Young DM, Tropsha A. Quantitative structure-activity relationship modeling of rat acute toxicity by oral exposure. Chemical Research in Toxicology 2009;22(12):1913-1921. R832720 (2009)
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Presentation Metabolomic analysis of urine and liver after chronic alcohol treatment in C57BL/6J mice. None Bradford BU, Han J, Kosyk O, Shymonyak S, Winnike J, Kono H, O’Connell T, Rusyn I Bradford BU, Han J, Kosyk O, Shymonyak S, Winnike J, Kono H, O’Connell T, Rusyn I. Metabolomic analysis of urine and liver after chronic alcohol treatment in C57BL/6J mice. Presented at the 58th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, November 2-6, 2007. R832720 (2007)
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Presentation NMR and microarray based analysis of mouse liver following exposure to trichloroethylene. None Bradford BU, Kim S, Kosyk O, Grimes J, O’Connell T, Rusyn I Bradford BU, Kim S, Kosyk O, Grimes J, O’Connell T, Rusyn I. NMR and microarray based analysis of mouse liver following exposure to trichloroethylene. Presented at the Society of Toxicology 49th Annual Meeting and ToxExpo, Salt Lake City, UT, March 7-10, 2010. R832720 (2009)
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Presentation Monte Carlo analysis of TCE metabolism across a panel of inbred mouse strains. None Campbell J, Clewell H, Kim S, Collins L, Kosyk O, Rusyn I Campbell J, Clewell H, Kim S, Collins L, Kosyk O, Rusyn I. Monte Carlo analysis of TCE metabolism across a panel of inbred mouse strains. Presented at the Society of Toxicology 49th Annual Meeting and ToxExpo, Salt Lake City, UT, March 7-10, 2010. R832720 (2009)
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Presentation Approximate Bayesian approaches for quantitative trait loci estimation. None Chang Y-L, Zou F, Wright FA Chang Y-L, Zou F, Wright FA. Approximate Bayesian approaches for quantitative trait loci estimation. Presented at the International Biometric Society's Eastern North American Region (ENAR) Spring Meeting, Atlanta, GA, March 11-14, 2007 (contributed presentation). R832720 (2007)
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Presentation Approximate Bayesian approaches for quantitative trait loci estimation. None Chang Y-L, Zou F, Wright FA Chang Y-L, Zou F, Wright FA. Approximate Bayesian approaches for quantitative trait loci estimation. Presented at the Biostatistics Colloquium, Department of Biostatistics, University of North Carolina, Chapel Hill, NC, 2007. R832720 (2007)
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Presentation Multi-strain study of trichoroethylene toxicity in mice. None DeSimone MC, Harbourt D, Boysen G, Collins L DeSimone MC, Harbourt D, Boysen G, Collins L, et al. Multi-strain study of trichoroethylene toxicity in mice. Presented at the Superfund Basic Research Program Annual Meeting: New Technologies to Assess Environmental Exposure, San Diego, CA, December 10-12, 2006. R832720 (2006)
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Presentation Development of EPA’s ToxCast program for prioritizing the toxicity testing of environmental chemicals. None Dix D, Martin MT, Li Z, Judson R, Houck KA Dix D, Martin MT, Li Z, Judson R, Houck KA. Development of EPA’s ToxCast program for prioritizing the toxicity testing of environmental chemicals. Presented at the Society for Biomolecular Sciences 13th Annual Conference and Exhibition, Montreal, Canada, April 15-19, 2007. R832720 (2007)
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Presentation EPA’s ToxCast program for predicting hazard and prioritizing toxicity testing of environmental chemicals. None Dix D, Judson R, Kavlock R, Li Z, Martin M, Richard A, Setzer W, Houck K Dix D, Judson R, Kavlock R, Li Z, Martin M, Richard A, Setzer W, Houck K. EPA’s ToxCast program for predicting hazard and prioritizing toxicity testing of environmental chemicals. Presented at the 2007 International Science Forum on Computational Toxicology, Research Triangle Park, NC, May 21-23, 2007. R832720 (2007)
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Presentation Quantitative structure toxicity relationships (QSTR) models for predicting acute/sub-acute and sub-chronic/chronic adverse effect levels. None Easterling M, Tropsha A, Ye L, Pirone J, Zhu H, Martin T, Moudgal C Easterling M, Tropsha A, Ye L, Pirone J, Zhu H, Martin T, Moudgal C. Quantitative structure toxicity relationships (QSTR) models for predicting acute/sub-acute and sub-chronic/chronic adverse effect levels. Presented at the Society of Toxicology 48th Annual Meeting and ToxExpo, Baltimore, MD, March 15-19, 2009. R832720 (2009)
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Presentation Analysis for MAQC toxicogenomics datasets. None Elloumi F, Li Z, Judson R Elloumi F, Li Z, Judson R. EPA Analysis for MAQC toxicogenomics datasets. Presented at the 8th MAQC Project Meeting: Development and Validation of Predictive Models, Washington, DC, March 24-26, 2008. R832720 (2008)
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Presentation Response profiles from toxicogenomics data. None Elloumi F, Judson R, Dix D, Shah I, Knudsen T, Reif D, Singh A, Li Z, Wright FA Elloumi F, Judson R, Dix D, Shah I, Knudsen T, Reif D, Singh A, Li Z, Wright FA. Response profiles from toxicogenomics data. Presented at the Society of Toxicology 48th Annual Meeting and ToxExpo, Baltimore, MD, March 15-19, 2009. R832720 (2009)
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Presentation Fast association mapping using summation trees. None Gatti DM, Shabalin AA, Rusyn I, Wright FA, Nobel AB Gatti DM, Shabalin AA, Rusyn I, Wright FA, Nobel AB. Fast association mapping using summation trees. Presented at the 7th Annual Meeting of the Complex Trait Consortium, Montreal, Canada, May 31-June 3, 2008. R832720 (2008)
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Presentation Examination of genetic networks that regulate gene expression in liver using complex trait analysis. None Gatti D, Maki A, Chesler EJ, Kirova R Gatti D, Maki A, Chesler EJ, Kirova R, et al. Examination of genetic networks that regulate gene expression in liver using complex trait analysis. Presented at the 46th Society of Toxicology Annual Meeting, Charlotte, NC, March 25-29, 2007. R832720 (2006)
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Presentation QSAR/QSTR analysis of imbalanced datasets using k-Nearest Neighbors approach. None Golbraikh A, Zhu H, Ye L, Wang-Bell M, Tang H, Tropsha A Golbraikh A, Zhu H, Ye L, Wang-Bell M, Tang H, Tropsha A. QSAR/QSTR analysis of imbalanced datasets using k-Nearest Neighbors approach. Presented at the Fourth International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources, Moscow, Russia, September 11-15, 2007. R832720 (2007)
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Presentation Automatic detection of outliers prior to QSAR studies. None Golbraikh A, Zhu H, Ye L, Wang-Bell M, Tang H, Tropsha A Golbraikh A, Zhu H, Ye L, Wang-Bell M, Tang H, Tropsha A. Automatic detection of outliers prior to QSAR studies. Presented at the 235th American Chemical Society National Meeting, New Orleans, LA, April 6-10, 2008. R832720 (2008)
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Presentation Analysis of trichloroethylene metabolism in a genetically diverse panel of inbred mouse strains. None Grimes J, Kim S, O'Connell T, Bradford B, Rusyn I Grimes J, Kim S, O'Connell T, Bradford B, Rusyn I. Analysis of trichloroethylene metabolism in a genetically diverse panel of inbred mouse strains. Presented at the 5th International Metabolomics Society Conference, Edmonton, Alberta, Canada, August 30-September 2, 2009. R832720 (2009)
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Presentation High-throughput metabolite profiling of serum from trichloroethylene-exposed mice by direct infusion FTICR-MS. None Han J, Harbourt D, Danell RM, Borchers CH Han J, Harbourt D, Danell RM, Borchers CH, et al. High-throughput metabolite profiling of serum from trichloroethylene-exposed mice by direct infusion FTICR-MS. Presented at the Superfund Basic Research Program Annual Meeting: New Technologies to Assess Environmental Exposure, San Diego, CA, December 10-12, 2006. R832720 (2006)
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Presentation In vitro screening for chemical toxicity in a genetically-diverse human model system. None Hatcher S, Kosyk O, Ross P, Wright FA, Schwartz J, Dix D, Rusyn I Hatcher S, Kosyk O, Ross P, Wright FA, Schwartz J, Dix D, Rusyn I. In vitro screening for chemical toxicity in a genetically-diverse human model system. Poster presented at the EPA ToxCast Data Analysis Summit, Research Triangle Park, NC, May 14-15, 2009. R832720 (2009)
Presentation Toxicogenetic dimension in studies of the mechanisms of liver injury. None Hege A, Ross P, Su S, Stylianou I Hege A, Ross P, Su S, Stylianou I, et al. Toxicogenetic dimension in studies of the mechanisms of liver injury. Presented at the U.S. Environmental Protection Agency Science Forum, Washington, DC, May 16-18, 2006. R832720 (2006)
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Presentation Cross-species association mapping identifies genetic risk factors for liver toxicity. None Hege A, Ross P, Balletta L, Bradford B Hege A, Ross P, Balletta L, Bradford B, et al. Cross-species association mapping identifies genetic risk factors for liver toxicity. Presented at the 46th Society of Toxicology Annual Meeting, Charlotte, NC, March 25-29, 2007. R832720 (2006)
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Presentation Phenotypic anchoring of gene expression data from acetaminophen hepatotoxicity studies in the mouse model of the human population reveals biomarkers of response. None Hege A, Ross PK, Threadgill DW, Rusyn I Hege A, Ross PK, Threadgill DW, Rusyn I. Phenotypic anchoring of gene expression data from acetaminophen hepatotoxicity studies in the mouse model of the human population reveals biomarkers of response. Presented at the Society of Toxicology 47th Annual Meeting & ToxExpo, Seattle, WA, March 16-20, 2008. R832720 (2007)
R832720 (2008)
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Presentation U.S. EPA’s ToxCast program for predicting hazard and prioritizing toxicity testing of environmental chemicals. None Kavlock RJ, Dix D, Judson R, Li Z, Martin M, Richard A, Setzer W, Houck K Kavlock RJ, Dix D, Judson R, Li Z, Martin M, Richard A, Setzer W, Houck K. U.S. EPA’s ToxCast program for predicting hazard and prioritizing toxicity testing of environmental chemicals. Presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan, August 21-25, 2007. R832720 (2007)
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Presentation Analysis of trichloroethylene metabolism in a genetically diverse panel of mouse inbred strains. None Kim S-K, DeSimone MC, Harbourt D, Boysen G, Collins L, Waidyanatha S, Bradford BU, Threadgill DW, Rusyn I Kim S-K, DeSimone MC, Harbourt D, Boysen G, Collins L, Waidyanatha S, Bradford BU, Threadgill DW, Rusyn I. Analysis of trichloroethylene metabolism in a genetically diverse panel of mouse inbred strains. Presented at the Society of Toxicology 47th Annual Meeting & ToxExpo, Seattle, WA, March 16-20, 2008. R832720 (2007)
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Presentation Using aspects to create interconnected analysis tool networks. None Lee K, Stotts D Lee K, Stotts D. Using aspects to create interconnected analysis tool networks. Presented at the International Symposium on Bioinformatics Research and Applications, Athens, GA, May 6-8, 2008. R832720 (2007)
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Presentation Visualization of features in curve estimates and application to genetic loci mapping. None Lee MH, Rusyn I, Threadgill DW, Marron JS Lee MH, Rusyn I, Threadgill DW, Marron JS. Visualization of features in curve estimates and application to genetic loci mapping. Presented at the Joint Statistical Meeting of the American Statistical Association, Seattle, WA, August 6-10, 2006. R832720 (2006)
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Presentation Age-dependent heterogeneity of gene expression in Fisher 344 rat retina. None Li Z, Wright FA, Royland JE Li Z, Wright FA, Royland JE. Age-dependent heterogeneity of gene expression in Fisher 344 rat retina. Presented at the Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 25-29, 2007. R832720 (2007)
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Presentation Discovering relevant pathways in microarray experiments-a tutorial on honest testing methods. None Li Z, Wright FA Li Z, Wright FA. Discovering relevant pathways in microarray experiments-a tutorial on honest testing methods. Presented at the U.S. Environmental Protection Agency's Info on Informatics Series, Research Triangle Park, NC, 2007. R832720 (2007)
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Presentation Significance analysis of variation change in gene expression studies. None Li Z, Wright FA, Royland JE Li Z, Wright FA, Royland JE. Significance analysis of variation change in gene expression studies. Presented at the 15th Annual International Conference on Intelligent Systems for Molecular Biology and 6th Annual European Conference on Computational Biology, Vienna, Austria, July 21-15, 2007. R832720 (2007)
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Presentation Chemical toxicity prediction for ToxCast Phase I. None Li Z, Wright FA, Elloumi F Li Z, Wright FA, Elloumi F. Chemical toxicity prediction for ToxCast Phase I. Presented at the Society of Toxicology 47th Annual Meeting & ToxExpo, Seattle, WA, March 16-20, 2008. R832720 (2007)
R832720 (2008)
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Presentation Dose-response pathway analysis for gene expression microarrays. None Li Z, Rusyn I, Wright FA Li Z, Rusyn I, Wright FA. Dose-response pathway analysis for gene expression microarrays. Presented at the Symposium on Toxicity Pathway-Based Risk Assessment: Preparing for Paradigm Change, The National Academy of Sciences, Washington, DC, May 11-13, 2009. R832720 (2009)
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Presentation Dose-response pathway analysis for gene expression microarrays. None Li Z, Rusyn I, Wright FA Li Z, Rusyn I, Wright FA. Dose-response pathway analysis for gene expression microarrays. Presented at the Society of Toxicology 49th Annual Meeting and ToxExpo, Salt Lake City, UT, March 7-10, 2010. R832720 (2009)
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Presentation A fast Bayesian method for eQTL linkage analysis in experimental crosses. None Liu J, Chang Y-L, Zou F, Wright FA Liu J, Chang Y-L, Zou F, Wright FA. A fast Bayesian method for eQTL linkage analysis in experimental crosses. Presented at the 2007 Joint Statistical Meetings, Salt Lake City, UT, July 29-August 2, 2007. R832720 (2007)
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Presentation Development of the in vitro toxicogenetic models for hepatotoxicity. None Martinez S, Bradford B, Kaiser R, Soldatow V, Amaral K, Ferguson S, Black C, LecLuyse E, Rusyn I Martinez S, Bradford B, Kaiser R, Soldatow V, Amaral K, Ferguson S, Black C, LecLuyse E, Rusyn I. Development of the in vitro toxicogenetic models for hepatotoxicity. Presented at the Society of Toxicology 48th Annual Meeting and ToxExpo, Baltimore, MD, March 15-19, 2009. R832720 (2008)
R833825 (2008)
R833825 (Final)
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Presentation Development of in vitro toxicogenetic models for hepatotoxicity. None Martinez S, Bradford B, Kaiser R, Soldatow V, Amaral K, Ferguson S, Black C, LecLuyse E, Rusyn I Martinez S, Bradford B, Kaiser R, Soldatow V, Amaral K, Ferguson S, Black C, LecLuyse E, Rusyn I. Development of in vitro toxicogenetic models for hepatotoxicity. Presented at the EPA ToxCast Data Analysis Summit, Research Triangle Park, NC, May 14-15, 2009. R832720 (2009)
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Presentation In vitro screening for population variability in chemical toxicity. None O'Shea SH, Schwarz J, Kosyk O, Ross PK, Wright FA, Tice RR, Dix DJ, Rusyn I O’Shea SH, Schwarz J, Kosyk O, Ross PK, Wright FA, Tice RR, Dix DJ, Rusyn I. In vitro screening for population variability in chemical toxicity. Presented at the Society of Toxicology 49th Annual Meeting and ToxExpo, Salt Lake City, UT, March 7-10, 2010. R832720 (2009)
R833825 (Final)
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Presentation QSAR Modeling of Human Liver Adverse Effects Database Using kNN method. None Rodgers AD, Zhu H, Rusyn I, Tropsha A Rodgers AD, Zhu H, Rusyn I, Tropsha A. QSAR modeling of human liver adverse effects database using kNN method. Presented at the Society of Toxicology 47th Annual Meeting & ToxExpo, Seattle, WA, March 16-20, 2008. R832720 (2008)
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Presentation Time-course comparison of gene expression signatures of xenobiotic activators of car and PPAR-alpha in mouse liver. None Ross PL, Woods, CG, Bradford BU, Kosyk O, Rusyn I Ross PL, Woods, CG, Bradford BU, Kosyk O, Rusyn I. Time-course comparison of gene expression signatures of xenobiotic activators of car and PPAR-alpha in mouse liver. Presented at the Society of Toxicology 47th Annual Meeting & ToxExpo, Seattle, WA, March 16-20, 2008. R832720 (2008)
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Presentation Genetical genomics and liver toxicology. None Rusyn I Rusyn I. Genetical genomics and liver toxicology. Presented at the Society of Toxicology 47th Annual Meeting & ToxExpo, Seattle, WA, March 16-20, 2008. R832720 (2008)
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Presentation Use of inbred mouse strains to model genetic variation in susceptibility to drug-induced liver injury. None Rusyn I Rusyn I. Use of inbred mouse strains to model genetic variation in susceptibility to drug-induced liver injury. Presented at the Hepatotoxicity Summit, Philadelphia, PA, 2008. R832720 (2008)
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Presentation Using in vitro dose-response profiles to enhance QSAR modeling of in vivo toxicity. None Sedykh A, Zhu H, Tang H, Zhang L, Richard A, Rusyn I, Tropsha A Sedykh A, Zhu H, Tang H, Zhang L, Richard A, Rusyn I, Tropsha A. Using in vitro dose-response profiles to enhance QSAR modeling of in vivo toxicity. Presented at the Society of Toxicology 49th Annual Meeting and ToxExpo, Salt Lake City, UT, March 7-10, 2010. R832720 (2009)
R833825 (Final)
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Presentation Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. None Tropsha A Tropsha A. Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. Presented at the Fourth International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources, Moscow, Russia, September 11-15, 2007. R832720 (2007)
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Presentation Applicability domains, space coverage, and predictive power of QSAR models. None Tropsha A, Golbraikh A, Zhu H Tropsha A, Golbraikh A, Zhu H. Applicability domains, space coverage, and predictive power of QSAR models. Presented at the 235th American Chemical Society National Meeting, New Orleans, LA, April 6-10, 2008. R832720 (2008)
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Presentation Toxico-cheminformatics and QSPR modeling of the carcinogenic potency database. None Wang K, Richard A, Rusyn I, Tropsha A Wang K, Richard A, Rusyn I, Tropsha A. Toxico-cheminformatics and QSPR modeling of the carcinogenic potency database. Presented at the 46th Society of Toxicity Annual Meeting, Charlotte, NC, March 25-29, 2007. R832720 (2006)
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Presentation Pharmaco-metabolomics and the prediction of hepatotoxicity. None Winnike JH, Li Z, Wright FA, Macdonald JM, O’Connell TM, Watkins PB Winnike JH, Li Z, Wright FA, Macdonald JM, O’Connell TM, Watkins PB. Pharmaco-metabolomics and the prediction of hepatotoxicity. Presented to the Research Triangle Park Drug Metabolism Discussion Group, Research Triangle Park, NC, 2007. R832720 (2007)
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Presentation Hypothesis tests of functional categories in microarray data–a new approach. None Wright FA, Nobel AB, Barry WT Wright FA, Nobel AB, Barry WT. Hypothesis tests of functional categories in microarray data–a new approach. Presented at the UIUC Bioinformatics Seminar Series, Urbana-Champaign, IL, 2007. R832720 (2007)
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Presentation Prediction of in vivo toxicity endpoints from ToxCast Phase I data using a variety of machine learning approaches. None Wright FA, Li Z, Huang HW, Ghosh A, Sun W, Zou F, Rusyn I Wright FA, Li Z, Huang HW, Ghosh A, Sun W, Zou F, Rusyn I. Prediction of in vivo toxicity endpoints from ToxCast Phase I data using a variety of machine learning approaches. Presented at the EPA ToxCast Data Analysis Summit, Research Triangle Park, NC, May 14-15, 2009. R832720 (2009)
Presentation Enhanced kNN-QSAR modeling of aquatic toxicity of diverse organic compounds tested by fathead minnow. None Ye L, Zhu H, Golbraikh A, Tropsha A Ye L, Zhu H, Golbraikh A, Tropsha A. Enhanced kNN-QSAR modeling of aquatic toxicity of diverse organic compounds tested by fathead minnow. Presented at the Microsoft eScience Workshop, Chapel Hill, NC, October 21, 2007. R832720 (2007)
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Presentation Establishing a balance between prediction accuracy and applicability domain of QSAR models. None Ye L, Zhu H, Golbraikh A, Tropsha A Ye L, Zhu H, Golbraikh A, Tropsha A. Establishing a balance between prediction accuracy and applicability domain of QSAR models. Presented at the 235th American Chemical Society National Meeting, New Orleans, LA, April 6-10, 2008. R832720 (2008)
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Presentation Cheminformatics analysis of EPA ToxCast chemical libraries to identify domains of applicability for predictive toxicity models and prioritize compounds for toxicity testing. None Zhang L, Zhu H, Rusyn I, Judson R, Dix D, Houck K, Martin M, Richard A, Kavlock R, Tropsha A Zhang L, Zhu H, Rusyn I, Judson R, Dix D, Houck K, Martin M, Richard A, Kavlock R, Tropsha A. Cheminformatics analysis of EPA ToxCast chemical libraries to identify domains of applicability for predictive toxicity models and prioritize compounds for toxicity testing. Presented at the Society of Toxicology 48th Annual Meeting and ToxExpo, Baltimore, MD, March 15-19, 2009. R832720 (2008)
R832720 (2009)
R833825 (2008)
R833825 (Final)
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Presentation Cheminformatics analysis of EPA ToxCast chemical libraries to develop predictive toxicity models and prioritize compounds for in vivo toxicity testing. None Zhang L, Zhu H, Rusyn I, Judson R, Dix D, Houck K, Martin M, Richard A, Kavlock R, Tropsha A Zhang L, Zhu H, Rusyn I, Judson R, Dix D, Houck K, Martin M, Richard A, Kavlock R, Tropsha A. Cheminformatics analysis of EPA ToxCast chemical libraries to develop predictive toxicity models and prioritize compounds for in vivo toxicity testing. Presented at the EPA ToxCast Data Analysis Summit, Research Triangle Park, NC, May 14-15, 2009. R832720 (2009)
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Presentation Genome-level analysis of genetic regulation of sex-specific gene expression in mouse liver. None Zhao N, Gatti DM, Rusyn I Zhao N, Gatti DM, Rusyn I. Genome-level analysis of genetic regulation of sex-specific gene expression in mouse liver. Presented at the Society of Toxicology 48th Annual Meeting and ToxExpo, Baltimore, MD, March 15-19, 2009. R832720 (2008)
R833825 (2008)
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Presentation The utilization of NTP-HTS data in predictive ADME/tox modeling. None Zhu H, Wang K, Rusyn I, Richard A, Tropsha A Zhu H, Wang K, Rusyn I, Richard A, Tropsha A. The utilization of NTP-HTS data in predictive ADME/tox modeling. Presented at the 46th Society of Toxicity Annual Meeting, Charlotte, NC, March 25-29, 2007. R832720 (2006)
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Presentation Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. None Zhu H, Tropsha A, Fourches D, Varnek A, Papa E, Gramatica P, Oberg T, Dao P, Cherkasov A, Tetko IV Zhu H, Tropsha A, Fourches D, Varnek A, Papa E, Gramatica P, Oberg T, Dao P, Cherkasov A, Tetko IV. Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. Presented at the 2007 International Science Forum on Computational Toxicology, Research Triangle Park, NC, May 21-23, 2007. R832720 (2007)
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Presentation Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. None Zhu H, Tropsha A, Fourches D, Varnek A, Papa E, Gramatica P, Oberg T, Dao P, Cherkasov A, Tetko IV Zhu H, Tropsha A, Fourches D, Varnek A, Papa E, Gramatica P, Oberg T, Dao P, Cherkasov A, Tetko IV. Combinational QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis. Presented at the Microsoft eScience Workshop, Chapel Hill, NC, October 21, 2007. R832720 (2007)
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Presentation The utilization of NTP-HTS data in predictive ADME/tox modeling. None Zhu H, Rusyn I, Richard A, Tropsha A Zhu H, Rusyn I, Richard A, Tropsha A. The utilization of NTP-HTS data in predictive ADME/tox modeling. Presented at the 2007 International Science Forum on Computational Toxicology, Research Triangle Park, NC, May 21-23, 2007. R832720 (2007)
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Presentation Two-step quantitative structure activity relationship modeling of in vivo toxicity using in vitro cytotoxicity data. None Zhu H, Ye L, Rusyn I, Richard A, Golbraikh A, Tropsha A Zhu H, Ye L, Rusyn I, Richard A, Golbraikh A, Tropsha A. Two-step quantitative structure activity relationship modeling of in vivo toxicity using in vitro cytotoxicity data. Presented at the Society of Toxicology 47th Annual Meeting & ToxExpo, Seattle, WA, March 16-20, 2008. R832720 (2008)
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Presentation Combinatorial QSAR modeling of rat acute toxicity by oral exposure. None Zhu H, Martin TM, Ye L, Young DM, Tropsha A Zhu H, Martin TM, Ye L, Young DM, Tropsha A. Combinatorial QSAR modeling of rat acute toxicity by oral exposure. Presented at the Society of Toxicology 48th Annual Meeting and ToxExpo, Baltimore, MD, March 15-19, 2009. R832720 (2009)
R833825 (2008)
R833825 (Final)
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Presentation Using ToxCast cell-viability and gene-expression assays as biological descriptors in QSAR modeling of animal toxicity endpoints. None Zhu H, Sedykh A, Zhang L, Rusyn I, Tropsha A Zhu H, Sedykh A, Zhang L, Rusyn I, Tropsha A. Using ToxCast cell-viability and gene-expression assays as biological descriptors in QSAR modeling of animal toxicity endpoints. Poster presented at the EPA ToxCast Data Analysis Summit, Research Triangle Park, NC, May 14-15, 2009. R832720 (2009)
R833825 (2008)
R833825 (Final)
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Proceedings Mining approximate frequent itemset in the presence of noise: algorithm and analysis. None Liu J, Paulsen S, Sun X, Wang W, Nobel A, Prins J Liu J, Paulsen S, Sun X, Wang W, Nobel A, Prins J. Mining approximate frequent itemset in the presence of noise: algorithm and analysis. In: Proceedings of the Sixth Society for Industrial and Applied Mathematics Conference on Data Mining, Bethesda, MD, April 20-22, 2006, pp. 405-416. R832720 (2006)
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Proceedings Clustering pair-wise dissimilarity data into partially ordered sets. None Liu J, Zhang Q, Wang W, McMillan L, Prins J Liu J, Zhang Q, Wang W, McMillan L, Prins J. Clustering pair-wise dissimilarity data into partially ordered sets. In: Proceedings of the 12th Association for Computer Machinery Special Interest Group on Knowledge Discovery and Data Mining, International Conference on Knowledge Discovery and Data Mining, Philadelphia, PA, August 20-23, 2006, pp. 637-642. R832720 (2006)
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Proceedings PoClustering: lossless clustering of dissimilarity data. None Liu J, Zhang Q, Wang W, McMillan L, Prins J Liu J, Zhang Q, Wang W, McMillan L, Prins J. PoClustering: lossless clustering of dissimilarity data. In: Proceedings of the 2007 SIAM International Conference on Data Mining, Radisson University Hotel, Minneapolis, MN, April 26-28, 2007. R832720 (2007)
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Proceedings Sample selection for maximal diversity. None Pan F, Roberts A, McMillan L, Pardo-Manuel de Villena F, Threadgill D, Wang W Pan F, Roberts A, McMillan L, Pardo-Manuel de Villena F, Threadgill D, Wang W. Sample selection for maximal diversity. In: Proceedings of the IEEE International Conference on Data Mining, Ohama, NE, October 28-31, 2007, pp. 262-271. R832720 (2007)
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Proceedings Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows. None Roberts A, McMillan L, Wang W, Parker J, Rusyn I, Threadgill D Roberts A, McMillan L, Wang W, Parker J, Rusyn I, Threadgill D. Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows. In: ISMB/ECCB 2007 Conference Proceedings 21-25 July 2007, Vienna, Italy. Bioinformatics 2007;23(13):i401-i407. R832720 (2007)
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Proceedings CARE: finding local linear correlations in high dimensional data. None Wang W, Zhang X, Pan F Wang W, Zhang X, Pan F. CARE:finding local linear correlations in high dimensional data. In: Proceedings of the 24th International Conference on Data Engineering, Cancun, Mexico, April 7-12, 2008. R832720 (2007)
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Proceedings Mining approximate order preserving clusters in the presence of noise. None Zhang M, Wang W, Liu J Zhang M, Wang W, Liu J. Mining approximate order preserving clusters in the presence of noise. In: Proceedings of the 24th International Conference on Data Engineering, Cancun, Mexico, April 7-12, 2008. R832720 (2007)
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Proceedings Mining coherent patterns from heterogeneous microarray data. None Zhang X, Wang W Zhang X, Wang W. Mining coherent patterns from heterogeneous microarray data. In:Proceedings of the 15th Association for Computer Machinery Conference on Information and Knowledge Management, Arlington, VA, November 6-11, 2006. R832720 (2006)
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Proceedings On demand phenotype ranking through subspace clustering. None Zhang X, Wang W, Huan J Zhang X, Wang W, Huan J. On demand phenotype ranking through subspace clustering. In: Proceedings of the 2007 SIAM International Conference on Data Mining, Radisson University Hotel, Minneapolis, MN, April 26-28, 2007. R832720 (2007)
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Proceedings An efficient algorithm for mining coherent patterns from heterogeneous microarrays. None Zhang X, Wang W Zhang X, Wang W. An efficient algorithm for mining coherent patterns from heterogeneous microarrays. In: Proceedings of the 19th International Conference on Statistical and Scientific Database Management (SSDBM) 2007, Banff, Canada, July 9-11, 2007. R832720 (2007)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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