TY  - Abstract
A1  - Easterling, M 
A1  - Tropsha, A 
A1  - Ye, L 
A1  - Pirone, J 
A1  - Zhu, H 
A1  - Martin, T 
A1  - Moudgal, C 
T1  - Quantitative structure toxicity relationships (QSTR) models for predicting acute/sub-acute and sub-chronic/chronic adverse effect levels.
Y1  - 2009/03/
N1  - R832720
VL  - 108
IS  - 1
SP  - 234
ER  - 


TY  - Abstract
A1  - Zhang, L 
A1  - Zhu, H 
A1  - Rusyn, I 
A1  - Judson, R 
T1  - Cheminformatics analysis of EPA ToxCast chemical libraries to identify domains of applicability for predictive toxicity models and prioritize compounds for toxicity testing.
Y1  - 2009/03/
N1  - R832720
VL  - 108
IS  - 1
SP  - 226
ER  - 


TY  - Abstract
A1  - Zhu, H 
A1  - Martin, T M
A1  - Ye, L 
A1  - Young, D M
T1  - Combinatorial QSAR modeling of rat acute toxicity by oral exposure.
Y1  - 2009/03/
N1  - R832720
VL  - 108
IS  - 1
SP  - 234
ER  - 


TY  - CHAP
A1  - Stotts, D 
A1  - Lee, K 
A1  - Rusyn, I 
T1  - Supporting Computational Systems Science:Genomic Analysis Tool Federations Using Aspects and AOP.
Y1  - 2008/04/
N1  - R832720
ER  - 


TY  - JOUR
A1  - Borysov, P 
A1  - Hannig, J 
A1  - Marron, J S
A1  - Muratov, E 
A1  - Fourches, D 
A1  - Tropsha, A 
T1  - Activity prediction and identification of mis-annotated chemical compounds using extreme descriptors.
Y1  - 2016/03/
N1  - R833825
N1  - R832720
JF  - JOURNAL OF CHEMOMETRICS
J1  - J CHEMOMETR
VL  - 30
IS  - 3
SP  - 99
EP  - 108
ER  - 


TY  - JOUR
A1  - Bradford, B U
A1  - O'Connell, T M
A1  - Han, J 
A1  - Kosyk, O 
A1  - Shymonyak, S 
A1  - Ross, P K
A1  - Winnike, J 
A1  - Kono, H 
A1  - Rusyn, I 
T1  - Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease.
Y1  - 2008/10/15
N1  - R832720
VL  - 232
IS  - 2
SP  - 236
EP  - 243
ER  - 


TY  - JOUR
A1  - Chen, M 
A1  - Ibrahim, J G
A1  - Chi, Y 
T1  - A new class of mixture models for differential gene expression in DNA microarray data.
Y1  - 2008/02/1
N1  - R832720
JF  - JOURNAL OF STATISTICAL PLANNING AND INFERENCE
J1  - J STAT PLAN INFER
VL  - 138
IS  - 2
SP  - 387
EP  - 404
ER  - 


TY  - JOUR
A1  - Fourches, D 
A1  - Barnes, J C
A1  - Day, N C
A1  - Bradley, P 
A1  - Reed, J Z
A1  - Tropsha, A 
T1  - Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Y1  - 2010/01/
N1  - R833825
N1  - R832720
JF  - CHEMICAL RESEARCH TOXICOLOGY
VL  - 23
IS  - 1
SP  - 171
EP  - 183
ER  - 


TY  - JOUR
A1  - Fourches, D 
A1  - Muratov, E 
A1  - Tropsha, A 
T1  - Trust, but verify: on the importance of chemical structure curation in cheminformatics and QSAR modeling research.
Y1  - 2010/07/26
N1  - R833825
N1  - R832720
JF  - JOURNAL OF CHEMICAL INFORMATION AND MODELING
J1  - Journal of Chemical Information and Modeling
J2  - Journal of Chemical Information and Modeling
VL  - 50
IS  - 7
SP  - 1189
EP  - 1204
ER  - 


TY  - JOUR
A1  - Fourches, D 
A1  - Muratov, E 
A1  - Ding, F 
A1  - Dokholyan, N V
A1  - Tropsha, A 
T1  - Predicting binding affinity of CSAR ligands using both structure-based and ligand-based approaches.
Y1  - 2013/08/26
N1  - R833825
N1  - R832720
JF  - JOURNAL OF CHEMICAL INFORMATION AND MODELING
J1  - Journal of Chemical Information and Modeling
J2  - Journal of Chemical Information and Modeling
VL  - 53
IS  - 8
SP  - 1915
EP  - 1922
ER  - 


TY  - JOUR
A1  - Gatti, D M
A1  - Shabalin, A A
A1  - Lam, T- C
A1  - Wright, F A
A1  - Rusyn, I 
A1  - Nobel, A B
T1  - FastMap: fast eQTL mapping in homozygous populations.
Y1  - 2009/02/15
N1  - R833825
N1  - R832720
VL  - 25
IS  - 4
SP  - 482
EP  - 489
ER  - 


TY  - JOUR
A1  - Gatti, D M
A1  - Sypa, M 
A1  - Rusyn, I 
A1  - Wright, F A
A1  - Barry, W T
T1  - SAFEGUI: resampling-based tests of categorical significance in gene expression data made easy.
Y1  - 2009/02/15
N1  - R833825
N1  - R832720
VL  - 25
IS  - 4
SP  - 541
EP  - 542
ER  - 


TY  - JOUR
A1  - Gatti, D M
A1  - Harrill, A H
A1  - Wright, F A
A1  - Threadgill, D W
A1  - Rusyn, I 
T1  - Replication and narrowing of gene expression quantitative trait loci using inbred mice.
Y1  - 2009/07/17
N1  - R833825
N1  - R832720
JF  - MAMMALIAN GENOME
J1  - MAMM GENOME
VL  - 20
IS  - 7
SP  - 437
EP  - 446
ER  - 


TY  - JOUR
A1  - Gatti, D 
A1  - Maki, A 
A1  - Chesler, E J
A1  - Kirova, R 
A1  - Kosyk, O 
A1  - Lu, L 
A1  - Manly, K F
A1  - Williams, R W
A1  - Perkins, A 
A1  - Langston, M A
A1  - Threadgill, D W
A1  - Rusyn, I 
T1  - Genome-level analysis of genetic regulation of liver gene expression networks.
Y1  - 2007/08/
N1  - R832720
JF  - HEPATOLOGY
J1  - HEPATOLOGY
VL  - 46
IS  - 2
SP  - 548
EP  - 557
ER  - 


TY  - JOUR
A1  - Gelfond, J 
A1  - Ibrahim, J G
A1  - Zou, F 
T1  - Proximity model for expression quantitative trait loci (eQTL) detection.
Y1  - 2007/12/
N1  - R832720
JF  - BIOMETRICS
J1  - BIOMETRICS
VL  - 63
IS  - 4
SP  - 1108
EP  - 1116
ER  - 


TY  - JOUR
A1  - Ghosh, A 
A1  - Zou, F 
A1  - Wright, F A
T1  - Estimating odds ratios in genome scans:an approximate conditional likelihood approach.
Y1  - 2008/05/9
N1  - R832720
VL  - 82
IS  - 5
SP  - 1064
EP  - 1074
ER  - 


TY  - JOUR
A1  - Graham, M R
A1  - Virtaneva, K 
A1  - Porcella, S F
A1  - Gardner, D J
A1  - Long, R D
A1  - Welty, D M
A1  - Barry, W T
A1  - Johnson, C A
A1  - Parkins, L D
A1  - Wright, F A
A1  - Musser, J M
T1  - Analysis of the transcriptome of Group A <em>Streptococcus</em> in mouse soft tissue infection.
Y1  - 2006/09/
N1  - R832720
JF  - AMERICAN JOURNAL OF PATHOLOGY
J1  - AM J PATHOL
VL  - 169
IS  - 3
SP  - 927
EP  - 942
ER  - 


TY  - JOUR
A1  - Gupta, M 
A1  - Ibrahim, J G
T1  - Variable selection in regression mixture modeling for the discovery of gene regulatory networks.
Y1  - 2007/09/1
N1  - R832720
JF  - JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
J1  - J AM STAT ASSOC
VL  - 102
IS  - 479
SP  - 867
EP  - 880
ER  - 


TY  - JOUR
A1  - Gupta, M 
T1  - Generalized hierarchical Markov models for the discovery of length-constrained sequence features from genome tiling arrays.
Y1  - 2007/09/
N1  - R832720
JF  - BIOMETRICS
J1  - BIOMETRICS
VL  - 63
IS  - 3
SP  - 797
EP  - 805
ER  - 


TY  - JOUR
A1  - Han, J 
A1  - Danell, R M
A1  - Patel, J R
A1  - Gumerov, D R
A1  - Scarlett, C O
A1  - Speir, J P
A1  - Parker, C E
A1  - Rusyn, I 
A1  - Zeisel, S 
A1  - Borchers, C 
T1  - Towards high throughput metabolomics using ultrahigh field Fourier transform ion cyclotron resonance mass spectrometry.
Y1  - 2008/06/
N1  - R832720
VL  - 4
IS  - 2
SP  - 128
EP  - 140
ER  - 


TY  - JOUR
A1  - Harrill, A H
A1  - Rusyn, I 
T1  - Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity.
Y1  - 2008/11/
N1  - R832720
VL  - 4
IS  - 11
SP  - 1379
EP  - 1389
ER  - 


TY  - JOUR
A1  - Harrill, A H
A1  - Ross, P K
A1  - Gatti, D M
A1  - Threadgill, D W
A1  - Rusyn, I 
T1  - Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel.
Y1  - 2009/07/
N1  - R833825
N1  - R832720
JF  - TOXICOLOGICAL SCIENCES
J1  - TOXICOL SCI
J2  - Toxicol.Sci.
J3  - Toxicological Sciences
VL  - 110
IS  - 1
SP  - 235
EP  - 243
ER  - 


TY  - JOUR
A1  - Harrill, A H
A1  - Watkins, P B
A1  - Su, S 
A1  - Ross, P K
A1  - Harbourt, D E
A1  - Stylianou, I M
A1  - Boorman, G A
A1  - Russo, M W
T1  - Mouse population-guided resequencing reveals that variants in <em>CD44</em> contribute to acetaminophen-induced liver injury in humans.
Y1  - 2009/09/
N1  - R832720
JF  - GENOME RESEARCH
J1  - GENOME RES
VL  - 19
IS  - 9
SP  - 1507
EP  - 1515
ER  - 


TY  - JOUR
A1  - Harrill, J A
A1  - Li, Z 
A1  - Wright, F A
A1  - Radio, N M
A1  - Mundy, W R
A1  - Tornero-Velez, R 
A1  - Crofton, K M
T1  - Transcriptional response of rat frontal cortex following acute <em>in vivo</em> exposure to the pyrethroid insecticides permethrin and deltamethrin.
Y1  - 2008/11/18
N1  - R832720
VL  - 9
SP  - 546
ER  - 


TY  - JOUR
A1  - Hu, J 
A1  - Wright, F A
A1  - Zou, F 
T1  - Estimation of expression indexes for oligonucleotide arrays using the singular value decomposition.
Y1  - 2006/03/
N1  - R832720
JF  - JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
J1  - J AM STAT ASSOC
VL  - 101
IS  - 473
SP  - 41
EP  - 50
ER  - 


TY  - JOUR
A1  - Hu, J 
A1  - Wright, F A
T1  - Assessing differential gene expression with small sample sizes in oligonucleotide arrays using a mean-variance model.
Y1  - 2007/03/
N1  - R832720
JF  - BIOMETRICS
J1  - BIOMETRICS
VL  - 63
IS  - 1
SP  - 41
EP  - 49
ER  - 


TY  - JOUR
A1  - Judson, R 
A1  - Elloumi, F 
A1  - Setzer, W R
A1  - Li, Z 
A1  - Shah, I 
T1  - A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scaledData model.
Y1  - 2008/05/19
N1  - R832720
VL  - 9
IS  - 241
SP  - 256
ER  - 


TY  - JOUR
A1  - Li, Z 
A1  - Wright, F A
A1  - Royland, J 
T1  - Age-dependent variability in gene expression in male Fischer 344 rat retina.
Y1  - 2009/01/18
N1  - R832720
VL  - 107
IS  - 1
SP  - 281
EP  - 292
ER  - 


TY  - JOUR
A1  - Liu, Y 
A1  - Hayes, D 
A1  - Nobel, A 
A1  - Marron, J 
T1  - Statistical Significance of Clustering for High-Dimension, Low–Sample Size Data
Y1  - 2012//01
N1  - R832720
JF  - JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
J1  - J AM STAT ASSOC
VL  - 103
IS  - 483
SP  - 1281
EP  - 1293
ER  - 


TY  - JOUR
A1  - Low, Y S
A1  - Sedykh, A Y
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays.
Y1  - 2014//
N1  - R833825
N1  - R832720
N1  - R835166
VL  - 14
IS  - 11
SP  - 1356
EP  - 1364
ER  - 


TY  - JOUR
A1  - Muratov, E N
A1  - Varlamova, E V
A1  - Artemenko, A G
A1  - Khristova, T 
A1  - Kuz'min, V E
A1  - Makarov, V A
A1  - Riabova, O B
A1  - Wutzler, P 
A1  - Schmidtke, M 
T1  - QSAR analysis of (biphenyloxy)propyl isoxazoles: agents against coxsackievirus B3.
Y1  - 2011/01/
N1  - R833825
N1  - R832720
JF  - FUTURE MEDICINAL CHEMISTRY
VL  - 3
IS  - 1
SP  - 15
EP  - 27
ER  - 


TY  - JOUR
A1  - Muratov, E N
A1  - Varlamova, E V
A1  - Artemenko, A G
A1  - Polishchuk, P G
A1  - Kuz'min, V E
T1  - Existing and developing approaches for QSAR analysis of mixtures.
Y1  - 2012/04/
N1  - R833825
N1  - R832720
JF  - MOLECULAR INFORMATICS
VL  - 31
IS  - 3-4
SP  - 202
EP  - 221
ER  - 


TY  - JOUR
A1  - Muratov, E N
A1  - Varlamova, E V
A1  - Artemenko, A G
A1  - Polishchuk, P G
A1  - Nikolaeva-Glomb, L 
A1  - Galabov, A S
A1  - Kuz'min, V E
T1  - QSAR analysis of poliovirus inhibition by dual combinations of antivirals.
Y1  - 2013/10/
N1  - R833825
N1  - R832720
JF  - STRUCTURAL CHEMISTRY
J1  - STRUCT CHEM
VL  - 24
IS  - 5
SP  - 1665
EP  - 1679
ER  - 


TY  - JOUR
A1  - Nadler, J J
A1  - Zou, F 
A1  - Huang, H 
A1  - Moy, S S
A1  - Lauder, J 
A1  - Crawley, J N
A1  - Threadgill, D W
A1  - Wright, F A
A1  - Magnuson, T R
T1  - Large-scale gene expression differences across brain regions and inbred strains correlates with a behavioral phenotype.
Y1  - 2006/11/
N1  - R832720
JF  - GENETICS
J1  - GENETICS
VL  - 174
IS  - 3
SP  - 1229
EP  - 1236
ER  - 


TY  - JOUR
A1  - Pogribny, I P
A1  - Tryndyak, V P
A1  - Bagnyukova, T V
A1  - Melnyk, S 
A1  - Montgomery, B 
A1  - Ross, S A
A1  - Latendresse, J R
A1  - Rusyn, I 
A1  - Beland, F A
T1  - Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet.
Y1  - 2009/07/
N1  - R832720
JF  - JOURNAL OF HEPATOLOGY
J1  - J HEPATOL
VL  - 51
IS  - 1
SP  - 176
EP  - 186
ER  - 


TY  - JOUR
A1  - Polishchuk, P G
A1  - Kuz'min, V E
A1  - Artemenko, A G
A1  - Muratov, E N
T1  - Universal approach for structural interpretation of QSAR/QSPR models.
Y1  - 2013/10/
N1  - R832720
JF  - MOLECULAR INFORMATICS
VL  - 32
IS  - 9-10
SP  - 843
EP  - 853
ER  - 


TY  - JOUR
A1  - Roberts, A 
A1  - Pardo-Manuel, D 
A1  - Wang, W 
A1  - McMillan, L 
A1  - Threadgill, D W
T1  - The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics.
Y1  - 2007/07/
N1  - R832720
JF  - MAMMALIAN GENOME
J1  - MAMM GENOME
VL  - 18
IS  - 6-7
SP  - 473
EP  - 481
ER  - 


TY  - JOUR
A1  - Scharph, R 
A1  - Tjelmeland, H 
A1  - Parmigiani, G 
A1  - Nobel, A 
T1  - A Bayesian Model for Cross-Study Differential Gene Expression
Y1  - 2012/01/01
N1  - R832720
JF  - JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
J1  - J AM STAT ASSOC
VL  - 104
IS  - 488
SP  - 1295
EP  - 1310
ER  - 


TY  - JOUR
A1  - Tetko, I V
A1  - Sushko, I 
A1  - Pandey, A K
A1  - Zhu, H 
A1  - Tropsha, A 
A1  - Papa, E 
A1  - Öberg, T 
A1  - Todeschini, R 
A1  - Fourches, D 
A1  - Varnek, A 
T1  - Critical Assessment of QSAR Models of Environmental Toxicity against Tetrahymena pyriformis:Focusing on Applicability Domain and Overfitting by Variable Selection.
Y1  - 2008/09/
N1  - R832720
VL  - 48
IS  - 9
SP  - 1733
EP  - 1746
ER  - 


TY  - JOUR
A1  - Tropsha, A 
A1  - Golbraikh, A 
T1  - Predictive QSAR modeling workflow, model applicability domains, and virtual screening.
Y1  - 2007//
N1  - R832720
JF  - CURRENT PHARMACEUTICAL DESIGN
J1  - CURR PHARM DESIGN
VL  - 13
IS  - 34
SP  - 3494
EP  - 3504
ER  - 


TY  - JOUR
A1  - Woods, C G
A1  - Kosyk, O 
A1  - Bradford, B U
A1  - Ross, P K
A1  - Burns, A M
A1  - Cunningham, M L
A1  - Qu, P 
A1  - Ibrahim, J G
A1  - Rusyn, I 
T1  - Time course investigation of PPARα- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression.
Y1  - 2007/12/
N1  - R832720
JF  - TOXICOLOGY AND APPLIED PHARMACOLOGY
J1  - TOXICOL APPL PHARM
J2  - Toxicol.Appl.Pharmacol.
J3  - Toxicol Appl Pharmacol
J4  - Toxicology and Applied Pharmacology
VL  - 225
IS  - 3
SP  - 267
EP  - 277
ER  - 


TY  - JOUR
A1  - Woods, C G
A1  - Vanden, H 
A1  - Rusyn, I 
T1  - Genomic profiling in nuclear receptor-mediated toxicity.
Y1  - 2007/06/
N1  - R832720
JF  - TOXICOLOGIC PATHOLOGY
J1  - TOXICOL PATHOL
VL  - 35
IS  - 4
SP  - 474
EP  - 494
ER  - 


TY  - JOUR
A1  - Wright, F A
A1  - Huang, H 
A1  - Guan, X 
A1  - Gamiel, K 
A1  - Jeffries, C 
A1  - Barry, W T
A1  - Pardo-Manuel, D 
A1  - Sullivan, P F
A1  - Wilhelmsen, K C
A1  - Zou, F 
T1  - Simulating association studies: a data-based resampling method for candidate regions or whole genome scans.
Y1  - 2007/10/1
N1  - R832720
JF  - BIOINFORMATICS
J1  - BIOINFORMATICS
J2  - LECT NOTES COMPUT SC
J3  - METHOD BIOCHEM ANAL
VL  - 23
IS  - 19
SP  - 2581
EP  - 2588
ER  - 


TY  - JOUR
A1  - Zhu, H 
A1  - Tropsha, A 
A1  - Fourches, D 
A1  - Varnek, A 
A1  - Papa, E 
A1  - Gramatica, P 
A1  - Oberg, T 
A1  - Dao, P 
A1  - Cherkasov, A 
A1  - Tetko, I 
T1  - Combinatorial QSAR Modeling of Chemical Toxicants Tested against Tetrahymena pyriformis.
Y1  - 2008/04/
N1  - R832720
VL  - 48
IS  - 4
SP  - 766
EP  - 784
ER  - 


TY  - JOUR
A1  - Zhu, H 
A1  - Rusyn, I 
A1  - Richard, A 
A1  - Tropsha, A 
T1  - Use of cell viability assay data improves the prediction accuracy of conventional quantitative structure-activity relationship models of animal carcinogenicity.
Y1  - 2008/04/
N1  - R833825
N1  - R832720
VL  - 116
IS  - 4
SP  - 506
EP  - 513
ER  - 


TY  - JOUR
A1  - Zhu, H 
A1  - Ye, L 
A1  - Richard, A 
A1  - Golbraikh, A 
A1  - Wright, F A
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - A novel two-step hierarchical quantitative structure-activity relationship modeling work flow for predicting acute toxicity of chemicals in rodents.
Y1  - 2009/08/
N1  - R833825
N1  - R832720
JF  - ENVIRONMENTAL HEALTH PERSPECTIVES
J1  - ENVIRON HEALTH PERSP
J2  - Environ.Health Perspect.
J3  - Environ Health Perspect
J4  - Environmental Health Perspectives
VL  - 117
IS  - 8
SP  - 1257
EP  - 1264
ER  - 


TY  - JOUR
A1  - Zhu, H 
A1  - Martin, T M
A1  - Ye, L 
A1  - Sedykh, A 
A1  - Young, D M
A1  - Tropsha, A 
T1  - Quantitative structure-activity relationship modeling of rat acute toxicity by oral exposure.
Y1  - 2009/12/
N1  - R833825
N1  - R832720
JF  - CHEMICAL RESEARCH TOXICOLOGY
VL  - 22
IS  - 12
SP  - 1913
EP  - 1921
ER  - 


TY  - CONF
A1  - Bradford, B U
A1  - Han, J 
A1  - Kosyk, O 
A1  - Shymonyak, S 
A1  - Winnike, J 
A1  - Kono, H 
A1  - O&rsquo;Connell, T 
A1  - Rusyn, I 
T1  - Metabolomic analysis of urine and liver after chronic alcohol treatment in C57BL/6J mice.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Bradford, B U
A1  - Kim, S 
A1  - Kosyk, O 
A1  - Grimes, J 
A1  - O’Connell, T 
A1  - Rusyn, I 
T1  - NMR and microarray based analysis of mouse liver following exposure to trichloroethylene.
Y1  - 2010/03/7-10
N1  - R832720
ER  - 


TY  - CONF
A1  - Campbell, J 
A1  - Clewell, H 
A1  - Kim, S 
A1  - Collins, L 
A1  - Kosyk, O 
A1  - Rusyn, I 
T1  - Monte Carlo analysis of TCE metabolism across a panel of inbred mouse strains.
Y1  - 2010/03/7-10
N1  - R832720
ER  - 


TY  - CONF
A1  - Chang, Y 
A1  - Zou, F 
A1  - Wright, F A
T1  - Approximate Bayesian approaches for quantitative trait loci estimation.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Chang, Y 
A1  - Zou, F 
A1  - Wright, F A
T1  - Approximate Bayesian approaches for quantitative trait loci estimation.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - DeSimone,   
A1  - Harbourt, D 
A1  - Boysen, G 
A1  - Collins, L 
T1  - Multi-strain study of trichoroethylene toxicity in mice.
Y1  - 2006/12/10-12
N1  - R832720
ER  - 


TY  - CONF
A1  - Dix, D 
A1  - Martin, M T
A1  - Li, Z 
A1  - Judson, R 
A1  - Houck, K A
T1  - Development of EPA&rsquo;s ToxCast program for prioritizing the toxicity testing of environmental chemicals.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Dix, D 
A1  - Judson, R 
A1  - Kavlock, R 
A1  - Li, Z 
A1  - Martin, M 
A1  - Richard, A 
A1  - Setzer, W 
A1  - Houck, K 
T1  - EPA&rsquo;s ToxCast program for predicting hazard and prioritizing toxicity testing of environmental chemicals.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Easterling, M 
A1  - Tropsha, A 
A1  - Ye, L 
A1  - Pirone, J 
A1  - Zhu, H 
A1  - Martin, T 
A1  - Moudgal, C 
T1  - Quantitative structure toxicity relationships (QSTR) models for predicting acute/sub-acute and sub-chronic/chronic adverse effect levels.
Y1  - 2009/03/15-19
N1  - R833825
N1  - R832720
ER  - 


TY  - CONF
A1  - Elloumi, F 
A1  - Li, Z 
A1  - Judson, R 
T1  - Analysis for MAQC toxicogenomics datasets.
Y1  - 2008/03/24-26
N1  - R832720
ER  - 


TY  - CONF
A1  - Elloumi, F 
A1  - Judson, R 
A1  - Dix, D 
A1  - Shah, I 
A1  - Knudsen, T 
A1  - Reif, D 
A1  - Singh, A 
A1  - Li, Z 
A1  - Wright, F A
T1  - Response profiles from toxicogenomics data.
Y1  - 2009/03/15-19
N1  - R832720
ER  - 


TY  - CONF
A1  - Gatti, D M
A1  - Shabalin, A A
A1  - Rusyn, I 
A1  - Wright, F A
A1  - Nobel, A B
T1  - Fast association mapping using summation trees.
Y1  - 2008//
N1  - R832720
ER  - 


TY  - CONF
A1  - Gatti, D 
A1  - Maki, A 
A1  - Chesler, E J
A1  - Kirova, R 
T1  - Examination of genetic networks that regulate gene expression in liver using complex trait analysis.
Y1  - 2007/03/25-29
N1  - R832720
ER  - 


TY  - CONF
A1  - Golbraikh, A 
A1  - Zhu, H 
A1  - Ye, L 
A1  - Wang-Bell, M 
A1  - Tang, H 
A1  - Tropsha, A 
T1  - QSAR/QSTR analysis of imbalanced datasets using k-Nearest Neighbors approach.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Golbraikh, A 
A1  - Zhu, H 
A1  - Ye, L 
A1  - Wang-Bell, M 
A1  - Tang, H 
A1  - Tropsha, A 
T1  - Automatic detection of outliers prior to QSAR studies.
Y1  - 2008/03/
N1  - R832720
ER  - 


TY  - CONF
A1  - Grimes, J 
A1  - Kim, S 
A1  - O'Connell, T 
A1  - Bradford, B 
A1  - Rusyn, I 
T1  - Analysis of trichloroethylene metabolism in a genetically diverse panel of inbred mouse strains.
Y1  - 2009/08/30-2
N1  - R832720
ER  - 


TY  - CONF
A1  - Han, J 
A1  - Harbourt, D 
A1  - Danell, R M
A1  - Borchers, C H
T1  - High-throughput metabolite profiling of serum from trichloroethylene-exposed mice by direct infusion FTICR-MS.
Y1  - 2006/12/10-12
N1  - R832720
ER  - 


TY  - CONF
A1  - Hatcher, S 
A1  - Kosyk, O 
A1  - Ross, P 
A1  - Wright, F A
A1  - Schwartz, J 
A1  - Dix, D 
A1  - Rusyn, I 
T1  - <em>In vitro</em> screening for chemical toxicity in a genetically-diverse human model system.
Y1  - 2009/05/14-15
N1  - R832720
ER  - 


TY  - CONF
A1  - Hege, A 
A1  - Ross, P 
A1  - Su, S 
A1  - Stylianou, I 
T1  - Toxicogenetic dimension in studies of the mechanisms of liver injury.
Y1  - 2006/05/16-18
N1  - R832720
ER  - 


TY  - CONF
A1  - Hege, A 
A1  - Ross, P 
A1  - Balletta, L 
A1  - Bradford, B 
T1  - Cross-species association mapping identifies genetic risk factors for liver toxicity.
Y1  - 2007/03/29
N1  - R832720
ER  - 


TY  - CONF
A1  - Hege, A 
A1  - Ross, P K
A1  - Threadgill, D W
A1  - Rusyn, I 
T1  - Phenotypic anchoring of gene expression data from acetaminophen hepatotoxicity studies in the mouse model of the human population reveals biomarkers of response.
Y1  - 2008//
N1  - R832720
ER  - 


TY  - CONF
A1  - Kavlock, R J
A1  - Dix, D 
A1  - Judson, R 
A1  - Li, Z 
A1  - Martin, M 
A1  - Richard, A 
A1  - Setzer, W 
A1  - Houck, K 
T1  - U.S. EPA&rsquo;s ToxCast program for predicting hazard and prioritizing toxicity testing of environmental chemicals.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Kim, S 
A1  - DeSimone, M C
A1  - Harbourt, D 
A1  - Boysen, G 
A1  - Collins, L 
A1  - Waidyanatha, S 
A1  - Bradford, B U
A1  - Threadgill, D W
A1  - Rusyn, I 
T1  - Analysis of trichloroethylene metabolism in a genetically diverse panel of mouse inbred strains.
Y1  - 2008//
N1  - R832720
ER  - 


TY  - CONF
A1  - Lee, K 
A1  - Stotts, D 
T1  - Using aspects to create interconnected analysis tool networks.
Y1  - 2008/05/6-8
N1  - R832720
ER  - 


TY  - CONF
A1  - Lee, M H
A1  - Rusyn, I 
A1  - Threadgill, D W
A1  - Marron, J S
T1  - Visualization of features in curve estimates and application to genetic loci mapping.
Y1  - 2006/08/6-10
N1  - R832720
ER  - 


TY  - CONF
A1  - Li, Z 
A1  - Wright, F A
A1  - Royland, J E
T1  - Age-dependent heterogeneity of gene expression in Fisher 344 rat retina.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Li, Z 
A1  - Wright, F A
T1  - Discovering relevant pathways in microarray experiments-a tutorial on honest testing methods.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Li, Z 
A1  - Wright, F A
A1  - Royland, J E
T1  - Significance analysis of variation change in gene expression studies.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Li, Z 
A1  - Wright, F A
A1  - Elloumi, F 
T1  - Chemical toxicity prediction for ToxCast Phase I.
Y1  - 2008//
N1  - R832720
ER  - 


TY  - CONF
A1  - Li, Z 
A1  - Rusyn, I 
A1  - Wright, F A
T1  - Dose-response pathway analysis for gene expression microarrays.
Y1  - 2009/05/11-13
N1  - R832720
ER  - 


TY  - CONF
A1  - Li, Z 
A1  - Rusyn, I 
A1  - Wright, F A
T1  - Dose-response pathway analysis for gene expression microarrays.
Y1  - 2010/03/7-10
N1  - R832720
ER  - 


TY  - CONF
A1  - Liu, J 
A1  - Chang, Y 
A1  - Zou, F 
A1  - Wright, F A
T1  - A fast Bayesian method for eQTL linkage analysis in experimental crosses.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Martinez, S 
A1  - Bradford, B 
A1  - Kaiser, R 
A1  - Soldatow, V 
A1  - Amaral, K 
A1  - Ferguson, S 
A1  - Black, C 
A1  - LecLuyse, E 
A1  - Rusyn, I 
T1  - Development of the <em>in vitro</em> toxicogenetic models for hepatotoxicity.
Y1  - 2009/03/15-19
N1  - R833825
N1  - R832720
ER  - 


TY  - CONF
A1  - Martinez, S 
A1  - Bradford, B 
A1  - Kaiser, R 
A1  - Soldatow, V 
T1  - Development of in vitro toxicogenetic models for hepatotoxicity.
Y1  - 2009/05/14-15
N1  - R832720
ER  - 


TY  - CONF
A1  - O'Shea, S H
A1  - Schwarz, J 
A1  - Kosyk, O 
A1  - Ross, P K
A1  - Wright, F A
A1  - Tice, R R
A1  - Dix, D J
A1  - Rusyn, I 
T1  - <em>In vitro</em> screening for population variability in chemical toxicity.
Y1  - 2010/03/7-10
N1  - R833825
N1  - R832720
ER  - 


TY  - CONF
A1  - Rodgers, A D
A1  - Zhu, H 
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - QSAR Modeling of Human Liver Adverse Effects Database Using kNN method.
Y1  - 2008/03/
N1  - R832720
ER  - 


TY  - CONF
A1  - Ross, P L
A1  - Woods,  
A1  - CG,  
A1  - Bradford, B U
A1  - Kosyk, O 
A1  - Rusyn, I 
T1  - Time-course comparison of gene expression signatures of xenobiotic activators of car and PPAR-alpha in mouse liver.
Y1  - 2008//
N1  - R832720
ER  - 


TY  - CONF
A1  - Rusyn, I 
T1  - Genetical genomics and liver toxicology.
Y1  - 2008//
N1  - R832720
ER  - 


TY  - CONF
A1  - Rusyn, I 
T1  - Use of inbred mouse strains to model genetic variation in susceptibility to drug-induced liver injury.
Y1  - 2008//
N1  - R832720
ER  - 


TY  - CONF
A1  - Sedykh, A 
A1  - Zhu, H 
A1  - Tang, H 
A1  - Zhang, L 
A1  - Richard, A 
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - Using <em>in vitro</em> dose-response profiles to enhance QSAR modeling of <em>in vivo</em> toxicity.
Y1  - 2010/03/7-10
N1  - R833825
N1  - R832720
ER  - 


TY  - CONF
A1  - Tropsha, A 
T1  - Combinational QSAR modeling of chemical toxicants tested against <em>Tetrahymena pyriformis</em>.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Tropsha, A 
A1  - Golbraikh, A 
A1  - Zhu, H 
T1  - Applicability domains, space coverage, and predictive power of QSAR models.
Y1  - 2008/03/
N1  - R832720
ER  - 


TY  - CONF
A1  - Wang, K 
A1  - Richard, A 
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - Toxico-cheminformatics and QSPR modeling of the carcinogenic potency database.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Winnike, J H
A1  - Li, Z 
A1  - Wright, F A
A1  - Macdonald, J M
A1  - O&rsquo;Connell, T M
A1  - Watkins, P B
T1  - Pharmaco-metabolomics and the prediction of hepatotoxicity.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Wright, F A
A1  - Nobel, A B
A1  - Barry, W T
T1  - Hypothesis tests of functional categories in microarray data&ndash;a new approach.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Wright, F A
A1  - Li, Z 
A1  - Huang, H W
A1  - Ghosh, A 
T1  - Prediction of <em>in vivo</em> toxicity endpoints from ToxCast Phase I data using a variety of machine learning approaches.
Y1  - 2009/05/14-15
N1  - R832720
ER  - 


TY  - CONF
A1  - Ye, L 
A1  - Zhu, H 
A1  - Golbraikh, A 
A1  - Tropsha, A 
T1  - Enhanced kNN-QSAR modeling of aquatic toxicity of diverse organic compounds tested by fathead minnow.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Ye, L 
A1  - Zhu, H 
A1  - Golbraikh, A 
A1  - Tropsha, A 
T1  - Establishing a balance between prediction accuracy and applicability domain of QSAR models.
Y1  - 2008/03/
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhang, L 
A1  - Zhu, H 
A1  - Rusyn, I 
A1  - Judson, R 
A1  - Dix, D 
A1  - Houck, K 
A1  - Martin, M 
A1  - Richard, A 
A1  - Kavlock, R 
A1  - Tropsha, A 
T1  - Cheminformatics analysis of EPA ToxCast chemical libraries to identify domains of applicability for predictive toxicity models and prioritize compounds for toxicity testing.
Y1  - 2009/03/15-19
N1  - R833825
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhang, L 
A1  - Zhu, H 
A1  - Rusyn, I 
A1  - Judson, R 
A1  - Dix, D 
A1  - Houck, K 
A1  - Martin, M 
A1  - Richard, A 
A1  - Kavlock, R 
A1  - Tropsha, A 
T1  - Cheminformatics analysis of EPA ToxCast chemical libraries to develop predictive toxicity models and prioritize compounds for <em>in vivo</em> toxicity testing.
Y1  - 2009/05/14-15
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhao, N 
A1  - Gatti, D M
A1  - Rusyn, I 
T1  - Genome-level analysis of genetic regulation of sex-specific gene expression in mouse liver.
Y1  - 2009/03/15-19
N1  - R833825
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhu, H 
A1  - Wang, K 
A1  - Rusyn, I 
A1  - Richard, A 
A1  - Tropsha, A 
T1  - The utilization of NTP-HTS data in predictive ADME/tox modeling.
Y1  - 2007/03/25-29
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhu, H 
A1  - Tropsha, A 
A1  - Fourches, D 
A1  - Varnek, A 
A1  - Papa, E 
A1  - Gramatica, P 
A1  - Oberg, T 
A1  - Dao, P 
A1  - Cherkasov, A 
A1  - Tetko, I V
T1  - Combinational QSAR modeling of chemical toxicants tested against <em>Tetrahymena pyriformis</em>.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhu, H 
A1  - Tropsha, A 
A1  - Fourches, D 
A1  - Varnek, A 
A1  - Papa, E 
A1  - Gramatica, P 
A1  - Oberg, T 
A1  - Dao, P 
A1  - Cherkasov, A 
A1  - Tetko, I V
T1  - Combinational QSAR modeling of chemical toxicants tested against <em>Tetrahymena pyriformis</em>.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhu, H 
A1  - Rusyn, I 
A1  - Richard, A 
A1  - Tropsha, A 
T1  - The utilization of NTP-HTS data in predictive ADME/tox modeling.
Y1  - 2007//
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhu, H 
A1  - Ye, L 
A1  - Rusyn, I 
A1  - Richard, A 
A1  - Golbraikh, A 
A1  - Tropsha, A 
T1  - Two-step quantitative structure activity relationship modeling of in vivo toxicity using in vitro cytotoxicity data.
Y1  - 2008/03/
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhu, H 
A1  - Martin, T M
A1  - Ye, L 
A1  - Young, D M
A1  - Tropsha, A 
T1  - Combinatorial QSAR modeling of rat acute toxicity by oral exposure.
Y1  - 2009/03/15-19
N1  - R833825
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhu, H 
A1  - Sedykh, A 
A1  - Zhang, L 
A1  - Rusyn, I 
A1  - Tropsha, A 
T1  - Using ToxCast cell-viability and gene-expression assays as biological descriptors in QSAR modeling of animal toxicity endpoints.
Y1  - 2009/05/14-15
N1  - R833825
N1  - R832720
ER  - 


TY  - CONF
A1  - Liu, J 
A1  - Paulsen, S 
A1  - Sun, X 
A1  - Wang, W 
A1  - Nobel, A 
A1  - Prins, J 
T1  - Mining approximate frequent itemset in the presence of noise: algorithm and analysis.
Y1  - 2006/04/20-22
N1  - R832720
ER  - 


TY  - CONF
A1  - Liu, J 
A1  - Zhang, Q 
A1  - Wang, W 
A1  - McMillan, L 
A1  - Prins, J 
T1  - Clustering pair-wise dissimilarity data into partially ordered sets.
Y1  - 2006/08/20-23
N1  - R832720
ER  - 


TY  - CONF
A1  - Liu, J 
A1  - Zhang, Q 
A1  - Wang, W 
A1  - McMillan, L 
A1  - Prins, J 
T1  - PoClustering: lossless clustering of dissimilarity data.
Y1  - 2007/04/26-28
N1  - R832720
ER  - 


TY  - CONF
A1  - Pan, F 
A1  - Roberts, A 
A1  - McMillan, L 
A1  - Pardo-Manuel, D 
A1  - Threadgill, D 
A1  - Wang, W 
T1  - Sample selection for maximal diversity.
Y1  - 2007/10/28-31
N1  - R832720
ER  - 


TY  - CONF
A1  - Roberts, A 
A1  - McMillan, L 
A1  - Wang, W 
A1  - Parker, J 
A1  - Rusyn, I 
A1  - Threadgill, D 
T1  - Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows.
Y1  - 2007/07/21-25
N1  - R832720
VL  - 23
IS  - 13
SP  - i401
EP  - i407
ER  - 


TY  - CONF
A1  - Wang, W 
A1  - Zhang, X 
A1  - Pan, F 
T1  - CARE: finding local linear correlations in high dimensional data.
Y1  - 2008/04/7-12
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhang, M 
A1  - Wang, W 
A1  - Liu, J 
T1  - Mining approximate order preserving clusters in the presence of noise.
Y1  - 2008/04/7-12
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhang, X 
A1  - Wang, W 
T1  - Mining coherent patterns from heterogeneous microarray data.
Y1  - 2006/11/6-11
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhang, X 
A1  - Wang, W 
A1  - Huan, J 
T1  - On demand phenotype ranking through subspace clustering.
Y1  - 2007/04/26-28
N1  - R832720
ER  - 


TY  - CONF
A1  - Zhang, X 
A1  - Wang, W 
T1  - An efficient algorithm for mining coherent patterns from heterogeneous microarrays.
Y1  - 2007/07/9-11
N1  - R832720
ER  -