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Grantee Research Project Results

Publications Details for Grant Number R829390C004

Developmental Effects of PCBs and Methylmercury

RFA: Centers for Children's Environmental Health and Disease Prevention Research (2001)

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Journal Article (3)
Presentation (4)
Reference Type Citation Progress Report Year Document Sources
Journal Article Bemis JC, Seegal RF. PCB-induced inhibition of the vesicular monoamine transporter predicts reductions in synaptosomal dopamine content. Toxicological Sciences 2004;80(2):288-295. R825812 (1999)
R829390 (2005)
R829390 (Final)
R829390C004 (2004)
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Journal Article Dreiem A, Gertz CC, Seegal RF. The effects of methylmercury on mitochondrial function and reactive oxygen species formation in rat striatal synaptosomes are age-dependent. Toxicological Sciences 2005;87(1):156-162. R829390 (2005)
R829390 (Final)
R829390C004 (2005)
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Journal Article Seegal RF, Brosch KO, Okoniewski RJ. Coplanar PCB congeners increase uterine weight and frontal cortical dopamine in the developing rat: implications for developmental neurotoxicity. Toxicological Sciences 2005;86(1):125-131. R829390 (2005)
R829390 (Final)
R829390C004 (2005)
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Presentation

Dreiem A, Seegal RF. Methylmercury alters mitochondrial function in rat striatal synaptosomes in a ROS independent manner. Presented at the 44th Annual Society of Toxicology ToxExpo, New Orleans, LA, March 6-10, 2005.

R829390C004 (2005)
not available
Presentation

Seegal RF, Bemis JC. Dopamine transporter inhibition is not sufficient to explain polychlorinated biphenyl induced reductions in synaptosomal tissue dopamine content. Presented at the 33rd Annual Meeting of the Society for Neuroscience, New Orleans, LA, Novermber 8-12, 2003.

R829390C004 (2004)
not available
Presentation

Seegal RF, Kaul S, Kanthasamy AG. A non-coplanar polychlorinated biphenyl induces oxidative stress and cell death in a mid-brain dopaminergic cell line. Presented at the 43rd Annual Society of Toxicology ToxExpo, Baltimore, MD, March 21-25, 2004.

R829390C004 (2004)
not available
Presentation

Seegal RF. Polychlorinated biphenyls and methylmercury alter neuronal function. Presented at the First International Joint Workshop of the Joint Research Centre and the Environmental and Occupational Health Sciences Institute—Modifiers of Chemical Toxicity: Implications for Human Health Risk Assessment, Poros/Athens, Greece, June 12-15, 2005.

R829390C004 (2005)
not available

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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