Grantee Research Project Results
Publications Details for Grant Number R826781
Human Health Effects of Exposure to Ultrafine Particles
RFA:
Health Effects of Particulate Matter and Associated Air Pollutants (1998)
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| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Abstract | Azadniv M, Torres A, Frasier LM, Daigle C, Speers DM, Utell MJ, Frampton MW. Serum inhibition of the oxidative burst in human polymorphonuclear leukocytes. American Journal of Respiratory and Critical Care Medicine 2001b;163:A991. |
R826781 (2001) R826781 (Final) |
not available |
| Abstract | Boscia JA, Chalupa D, Utell MJ, Zareba W, Konecki JA, Morrow PE, Gibb FR, Oberdorster G, Azadniv M, Frasier LM, Speers DM, Frampton MW. Airway and cardiovascular effects of inhaled ultrafine carbon particles in resting, healthy, nonsmoking adults. American Journal of Respiratory and Critical Care Medicine 2000;161:A239. |
R826781 (2000) R826781 (2001) R826781 (Final) |
not available |
| Abstract | Chalupa D, Morrow PE, Oberdorster G, Speers D, Daigle D, Utell MJ, Frampton MW. Deposition of ultrafine carbon particles in subjects with asthma. American Journal of Respiratory and Critical Care Medicine 2002;165:A829. |
R826781 (2001) R826781 (Final) |
not available |
| Abstract | Daigle CC, Speers DM, Chalupa D, Stewart JC, Frasier LM, Azadniv M, Phipps RP, Utell MJ, Frampton MW. Ultrafine particle exposure alters expression of CD40 ligand (CD154) in healthy subjects and subjects with asthma. American Journal of Respiratory and Critical Care Medicine 2002;165:A214. |
R826781 (2001) R826781 (Final) |
not available |
| Abstract | Frampton MW, Chalupa D, Morrow PE, Gibb FR, Oberdorster G, Boscia J, Speers DM, Utell MJ. Deposition of inhaled ultrafine carbon particles in resting healthy nonsmoking adults. American Journal of Respiratory and Critical Care Medicine 2000;161:A257. |
R826781 (2000) R826781 (2001) R826781 (Final) |
not available |
| Abstract | Frampton MW, Azadniv M, Chalupa D, Morrow PE, Gibb FR, Oberdorster G, Boscia J, Speers DM. Blood leukocyte expression of LFA-1 and (ICAM-1) after inhalation of ultrafine carbon particles. American Journal of Respiratory and Critical Care Medicine 2001;163:A264. |
R826781 (2000) R826781 (2001) R826781 (Final) |
not available |
| Abstract | Frampton MW, Zareba W, Daigle CC, Oberdorster G, Utell MJ. Inhalation of ultrafine particles alters myocardial repolarization in humans. American Journal of Respiratory and Critical Care Medicine 2002;165:B16. |
R826781 (2001) R826781 (Final) |
not available |
| Abstract | Frampton MW, Morrow PE, Oberdorster G, Pietropaoli AP, Utell MJ. Ultrafine particle inhalation in subjects with asthma: hematologic but not respiratory effects. American Journal of Respiratory and Critical Care Medicine 2003;167(7):A233. |
R826781 (Final) |
not available |
| Abstract | Pietropaoli AP, Perkins PT, Frasier LM, Frampton MW, Utell MJ, Hyde RW. In vitro measurement of nitric oxide diffusion when exposed to human blood and its components. American Journal of Respiratory and Critical Care Medicine 2003;167:A51. |
R826781 (Final) |
not available |
| Book Chapter | Chalupa DF, Gibb FR, Morrow PE, Oberdorster G, Riesenfeld E, Gelein R, Utell MJ, Frampton MW. A facility for controlled human exposures to ultrafine particles. In: Heinrich U, Mohr U, eds. Crucial Issues in Inhalation Research: Mechanistic, Clinical and Epidemiologic. INIS Monographs. Stuttgart, Germany: Fraunhofer IRB Verlag, 2002, pp. 241-253. |
R826781 (Final) R827354 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C004 (2011) |
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| Book Chapter | Frampton MW, Samet JM, Utell MJ. Exposures in outdoor air. In: Rosenstock L, Cullen MR, Brodkin CA, Redlich CA, eds. Textbook of Clinical, Occupational and Environmental Medicine, 2nd Edition. Philadelphia, PA: Elsevier Saunders, 2005, Chapter 51, pp. 1143-1149. |
R826781 (Final) |
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| Book Chapter | Frampton MW, Samet JM, Utell MJ. Exposures in outdoor air. In: Rosenstock L, Cullen MR, Brodkin CA, Redlich CA, eds. Textbook of Clinical, Occupational and Environmental Medicine, 2nd Edition. Philadelphia, PA: W.B. Saunders Company, 2005, pp. 1143-1149. |
R826781 (2001) |
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| Journal Article | Azadniv M, Torres A, Boscia J, Speers DM, Frasier LM, Utell MJ, Frampton MW. Neutrophils in lung inflammation: which reactive oxygen species are being measured? Inhalation Toxicology 2001;13(6):485-495. |
R826781 (2001) R826781 (Final) R827354 (2004) R827354 (Final) R827354C003 (2001) R827354C003 (2002) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Daigle CC, Chalupa DC, Gibb FR, Morrow PE, Oberdorster G, Utell MJ, Frampton MW. Ultrafine particle deposition in humans during rest and exercise. Inhalation Toxicology 2003;15(6):539-552. |
R826781 (2001) R826781 (Final) R827354 (2004) R827354 (Final) R827354C003 (1999) R827354C003 (2000) R827354C003 (2001) R827354C003 (2002) R827354C003 (2003) R827354C003 (2004) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Frampton MW. Systemic and cardiovascular effects of airway injury and inflammation: ultrafine particle exposure in humans. Environmental Health Perspectives 2001;109(Suppl 4):529-532. |
R826781 (2001) R826781 (Final) R827354 (Final) R827354C003 (2001) R827354C003 (2002) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Frampton MW, Stewart JC, Oberdorster G, Morrow PE, Chalupa D, Pietropaoli AP, Frasier LM, Speers DM, Cox C, Huang L-S, Utell MJ. Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans. Environmental Health Perspectives 2006;114(1):51-58. |
R826781 (Final) R827354 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Frampton MW. Does inhalation of ultrafine particles cause pulmonary vascular effects in humans? Inhalation Toxicology 2007;19(Suppl 1):75-79. |
R826781 (Final) R827354 (Final) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Geigel EJ, Hyde RW, Perillo IB, Torres A, Perkins PT, Pietropaoli AP, Frasier LM, Frampton MW, Utell MJ. Rate of nitric oxide production by lower alveolar airways of human lungs. Journal of Applied Physiology 1999;86(1):211-221. |
R826781 (2001) R826781 (Final) |
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| Journal Article | Huang YC, Schmitt M, Yang Z, Que LG, Stewart JC, Frampton MW, Devlin RB. Gene expression profile in circulating mononuclear cells after exposure to ultrafine carbon particles. Inhalation Toxicology 2010;22(10):835-846. |
R826781 (Final) R827354 (Final) |
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| Journal Article | Perillo IB, Hyde RW, Olszowka AJ, Pietropaoli AP, Frasier LM, Torres A, Perkins PT, Forster II RE, Utell MJ, Frampton MW. Chemiluminescent measurements of nitric oxide pulmonary diffusing capacity and alveolar production in humans. Journal of Applied Physiology 2001;91(5):1931-1940. |
R826781 (2001) R826781 (Final) |
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| Journal Article | Pietropaoli AP, Perillo IB, Torres A, Perkins PT, Frasier LM, Utell MJ, Frampton MW, Hyde RW. Simultaneous measurement of nitric oxide production by conducting and alveolar airways of humans. Journal of Applied Physiology 1999;87(4):1532-1542. |
R826781 (2001) R826781 (Final) |
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| Journal Article | Pietropaoli AP, Frampton MW, Hyde RW, Morrow PE, Oberdorster G, Cox C, Speers DM, Frasier LM, Chalupa DC, Huang L-S, Utell MJ. Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles. Inhalation Toxicology 2004;16(Suppl 1):59-72. |
R826781 (Final) R827354 (Final) R827354C003 (2003) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Riesenfeld E, Chalupa D, Gibb FR, Oberdo G, Gelein R, Morrow PE, Utell MJ, Frampton MW. Ultrafine particle concentrations in a hospital. Inhalation Toxicology 2000;12(Suppl 2):83-94. |
R826781 (2000) R826781 (2001) R826781 (Final) R827354 (Final) R827354C003 (2000) R827354C003 (2001) R827354C003 (2002) R827354C003 (Final) R827354C004 (2000) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Utell MJ, Frampton MW. Toxicologic methods: controlled human exposures. Environmental Health Perspectives 2000;108(Suppl 4):605-613. |
R826781 (Final) R827354 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Utell MJ, Frampton MW, Zareba W, Devlin RB, Cascio WE. Cardiovascular effects associated with air pollution:potential mechanisms and methods of testing. Inhalation Toxicology 2002;14(12):1231-1247. |
R826781 (2001) R826781 (Final) R827354 (Final) R827354C003 (2001) R827354C003 (2002) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Presentation | Frampton MW, Chalupa D, Morrow PE, Gibb FR, Oberdorster G, Speers DM, Utell MJ. Deposition and effects of inhaled ultrafine carbon particles in healthy subjects at rest. Presented at the PM2000: Particulate Matter and Health, Charleston, SC, January 24-28, 2000. |
R826781 (2000) R826781 (2001) R826781 (Final) |
not available |
| Proceedings | Chalupa DC, Gibb FR, Morrow PE, Oberdörster G, Reisenfeld E, Gelein R, Utell MJ, Frampton MW. A facility for controlled human exposures to ultrafine particles. In:Heinrich U, Mohr U, eds. Crucial Issues in Inhalation Research--Mechanistic, Clinical and Epidemiologic, 8th International Inhalation Symposium. Stuttgart, Germany: Fraunhofer IRB Verlag, 2002. |
R826781 (2001) R826781 (Final) R827354C003 (2001) |
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| Proceedings | Chalupa D, Gibb FR, Morrow PE, Oberdorster G, Riesenfeld E, Gelein R, Utell MJ, Frampton MW. A facility for controlled human exposures to ultrafine particles. In: Phalen RF, Bell YM, eds. Proceedings of the Third Colloquium on Particulate Air Pollution and Human Health, Health Effects Laboratory, University of California, Irvine, CA, APHEL Report No. 99-01, 1999, pp. 11-12. |
R826781 (2000) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.