Grantee Research Project Results
Journal Publications Details for Grant Number CR831455
National Environmental Respiratory Center: Health Hazards of Inhaled Gasoline Engine Emissions and Street Dust
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Journal Article | Effect of inhaled ultrafine carbon particles on the allergic airway response in ragweed-sensitized dogs. | INHALATION TOXICOLOGY | Barrett EG, Rudolph K, Bowen LE, Muggenburg BA, Bice DE | Barrett EG, Rudolph K, Bowen LE, Muggenburg BA, Bice DE. Effect of inhaled ultrafine carbon particles on the allergic airway response in ragweed-sensitized dogs. Inhalation Toxicology 2003;15(2):151-165. |
CR831455 (Final) |
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Journal Article | Effects of hardwood smoke exposure on allergic airway inflammation in mice. | INHALATION TOXICOLOGY | Barrett EG, Henson RD, Seilkop SK, McDonald JD, Reed MD | Barrett EG, Henson RD, Seilkop SK, McDonald JD, Reed MD. Effects of hardwood smoke exposure on allergic airway inflammation in mice. Inhalation Toxicology 2006;18(1):33-43. |
CR831455 (2006) CR831455 (Final) |
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Journal Article | Systemic immunotoxicity in AJ mice following 6-month whole body inhalation exposure to diesel exhaust. | TOXICOLOGY AND APPLIED PHARMACOLOGY | Burchiel SW, Lauer FT, McDonald JD, Reed MD | Burchiel SW, Lauer FT, McDonald JD, Reed MD. Systemic immunotoxicity in AJ mice following 6-month whole body inhalation exposure to diesel exhaust. Toxicology and Applied Pharmacology 2004;196(3):337-345. |
CR831455 (Final) |
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Journal Article | Hardwood smoke alters murine splenic T cell responses to mitogens following a 6-month whole body inhalation exposure. | TOXICOLOGY AND APPLIED PHARMACOLOGY | Burchiel SW, Lauer FT, Dunaway SL, Zawadzki J, McDonald JD, Reed MD | Burchiel SW, Lauer FT, Dunaway SL, Zawadzki J, McDonald JD, Reed MD. Hardwood smoke alters murine splenic T cell responses to mitogens following a 6-month whole body inhalation exposure. Toxicology and Applied Pharmacology 2005;202(3):229-236. |
CR831455 (2004) CR831455 (2006) CR831455 (Final) |
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Journal Article | Cardiovascular effects of inhaled diesel exhaust in spontaneously hypertensive rats. | CARIOVASCULAR TOXICOLOGY | Campen MJ, McDonald JD, Gigliotti AP, Seilkop SK, Reed MD, Benson JM | Campen MJ, McDonald JD, Gigliotti AP, Seilkop SK, Reed MD, Benson JM. Cardiovascular effects of inhaled diesel exhaust in spontaneously hypertensive rats. Cardiovascular Toxicology 2003;3(4):353-361. |
CR831455 (Final) |
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Journal Article | Fresh gasoline emissions, not paved road dust, trigger alterations in cardiac repolarization in ApoE-/- mice. | CARDIOVASCULAR TOXICOLOGY | Campen MJ, McDonald JD, Reed MD, Seagrave JC | Campen MJ, McDonald JD, Reed MD, Seagrave JC. Fresh gasoline emissions, not paved road dust, alter cardiac repolarization in ApoE-/- mice. Cardiovascular Toxicology 2006;6(3-4):199-209. |
CR831455 (Final) R830839 (2005) R830839 (Final) |
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Journal Article | Health effects of fine particulate air pollution: lines that connect (critical review discussion). | Journal of the Air and Waste Management Association | Chow JC, Watson JG, Mauderly JL, Costa DL, Wyzga RE, Vedal S, Hidy GM, Altshuler SL, Marrack D, Heuss JM, Wolff GT, Pope III CA, Dockery DW | Chow JC, Watson JG, Mauderly JL, Costa DL, Wyzga RE, Vedal S, Hidy GM, Altshuler SL, Marrack D, Heuss JM, Wolff GT, Pope III CA, Dockery DW. Health effects of fine particulate air pollution:lines that connect (critical review discussion). Journal of the Air & Waste Management Association 2006;56(10):1368-1380. |
CR831455 (Final) |
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Journal Article | Effects of gasoline engine emissions on preexisting allergic airway responses in mice. | INHALATION TOXICOLOGY | Day KC, Reed MD, McDonald JD, Seilkop SK, Barrett EG | Day KC, Reed MD, McDonald JD, Seilkop SK, Barrett EG. Effects of gasoline engine emissions on preexisting allergic airway responses in mice. Inhalation Toxicology 2008;20(13):1145-1155. |
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Journal Article | Increased susceptibility to RSV infection by exposure to inhaled diesel engine emissions. | AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY | Harrod KS, Jaramillo RJ, Rosenberger CL, Wang S-Z, Berger JA, McDonald JD, Reed MD | Harrod KS, Jaramillo RJ, Rosenberger CL, Wang S-Z, Berger JA, McDonald JD, Reed MD. Increased susceptibility to RSV infection by exposure to inhaled diesel engine emissions. American Journal of Respiratory Cell and Molecular Biology 2003;28(4):451-463. |
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Journal Article | Inhaled diesel engine emissions reduce bacterial clearance and exacerbate lung disease to Pseudomonas aeruginosa infection in vivo . | TOXICOLOGICAL SCIENCES | Harrod KS, Jaramillo RJ, Berger JA, Gigliotti AP, Seilkop SK, Reed MD | Harrod KS, Jaramillo RJ, Berger JA, Gigliotti AP, Seilkop SK, Reed MD. Inhaled diesel engine emissions reduce bacterial clearance and exacerbate lung disease to Pseudomonas aeruginosa infection in vivo . Toxicological Sciences 2005;83(1):155-165. |
CR831455 (2004) CR831455 (Final) |
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Journal Article | Gasoline exhaust emissions induce vascular remodeling pathways involved in atherosclerosis. | TOXICOLOGICAL SCIENCES | Lund AK, Knuckles TL, Akata CO, Shohet R, McDonald JD, Gigliotti A, Seagrave JC, Campen MJ | Lund AK, Knuckles TL, Akata CO, Shohet R, McDonald JD, Gigliotti A, Seagrave JC, Campen MJ. Gasoline exhaust emissions induce vascular remodeling pathways involved in atherosclerosis. Toxicological Sciences 2007;95(2):485-494. |
CR831455 (Final) R830839 (2005) R830839 (Final) R831860 (2007) R831860 (Final) |
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Journal Article | Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways. | ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY | Lund AK, Lucero J, Lucas S, Madden MC, McDonald JD, Seagrave J-C, Knuckles TL, Campen MJ | Lund AK, Lucero J, Lucas S, Madden MC, McDonald JD, Seagrave J-C, Knuckles TL, Campen MJ. Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1–mediated pathways. Arteriosclerosis, Thrombosis, and Vascular Biology 2009;29(4):511-517. |
CR831455 (Final) R830839 (2005) R830839 (Final) |
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Journal Article | Effects of concurrent ozone exposure on the pathogenesis of cigarette smoke-induced emphysema in B6C3F1 mice. | INHALATION TOXICOLOGY | March TH, Barr EB, Finch GL, Nikula KJ, Seagrave JC | March TH, Barr EB, Finch GL, Nikula KJ, Seagrave JC. Effects of concurrent ozone exposure on the pathogenesis of cigarette smoke-induced emphysema in B6C3F1 mice. Inhalation Toxicology 2002;14(12):1187-1213. |
CR831455 (Final) |
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Journal Article | An evolution of perspectives: summary of the Third Colloquium on Particulate Air Pollution and Human Health, Durham, North Carolina, June 6-8, 1999. | INHALATION TOXICOLOGY | Mauderly JL | Mauderly JL. An evolution of perspectives: summary of the Third Colloquium on Particulate Air Pollution and Human Health, Durham, North Carolina, June 6-8, 1999. Inhalation Toxicology 2000;12(Suppl 1):7-12. |
CR831455 (Final) |
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Journal Article | Animal models for the effect of age on susceptibility to inhaled particulate matter. | INHALATION TOXICOLOGY | Mauderly JL | Mauderly JL. Animal models for the effect of age on susceptibility to inhaled particulate matter. Inhalation Toxicology 2000;12(9):863-900. |
CR831455 (Final) |
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Journal Article | Diesel emissions: is more health research still needed? | TOXICOLOGICAL SCIENCES | Mauderly JL | Mauderly JL. Diesel emissions: is more health research still needed? Toxicological Sciences 2001;62(1):6-9. |
CR831455 (Final) |
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Journal Article | Health effects of air pollution: the struggle for context. | ENVIRONMENTAL PROGRESS | Mauderly JL | Mauderly JL. Health effects of air pollution: the struggle for context. Environmental Progress 2003;22(3):2-4. |
CR831455 (2004) CR831455 (2006) CR831455 (Final) |
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Journal Article | Health hazards of complex environmental exposures: a difficult challenge to inhalation toxicology. | INHALATION TOXICOLOGY | Mauderly JL | Mauderly JL. Health hazards of complex environmental exposures: a difficult challenge to inhalation toxicology. Inhalation Toxicology 2006;18(2):137-141. |
CR831455 (2006) CR831455 (Final) |
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Journal Article | Health effects of organic aerosols. | INHALATION TOXICOLOGY | Mauderly JL, Chow JC | Mauderly JL, Chow JC. Health effects of organic aerosols. Inhalation Toxicology 2008;20(3):257-288. |
CR831455 (Final) R831086 (Final) |
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Journal Article | Is there evidence for synergy among air pollutants in causing health effects? | ENVIRONMENTAL HEALTH PERSPECTIVES | Mauderly JL, Samet JM | Mauderly JL, Samet JM. Is there evidence for synergy among air pollutants in causing health effects? Environmental Health Perspectives 2009;117(1):1-6. |
CR831455 (Final) R832417 (Final) |
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Journal Article | Generation and characterization of four dilutions of diesel engine exhaust for a subchronic inhalation study. | ENVIRONMENTAL SCIENCE & TECHNOLOGY | McDonald JD, Barr EB, White RK, Chow JC, Schauer JJ, Zielinska B, Grosjean E | McDonald JD, Barr EB, White RK, Chow JC, Schauer JJ, Zielinska B, Grosjean E. Generation and characterization of four dilutions of diesel engine exhaust for a subchronic inhalation study. Environmental Science & Technology 2004;38(9):2513-2522. |
CR831455 (Final) |
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Journal Article | Generation and characterization of hardwood smoke inhalation exposure atmospheres. | AEROSOL SCIENCE & TECHNOLOGY | McDonald JD, White RK, Barr EB, Zielinska B, Chow JC, Grosjean E | McDonald JD, White RK, Barr EB, Zielinska B, Chow JC, Grosjean E. Generation and characterization of hardwood smoke inhalation exposure atmospheres. Aerosol Science & Technology 2006;40(8):573-584. |
CR831455 (2006) CR831455 (Final) |
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Journal Article | Generation and characterization of gasoline engine exhaust inhalation exposure atmospheres. | INHALATION TOXICOLOGY | McDonald JD, Barr EB, White RK, Kracko D, Chow JC, Zielinska B, Grosjean E | McDonald JD, Barr EB, White RK, Kracko D, Chow JC, Zielinska B, Grosjean E. Generation and characterization of gasoline engine exhaust inhalation exposure atmospheres. Inhalation Toxicology 2008;20(13):1157-1168. |
CR831455 (Final) |
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Journal Article | Short-term inhalation of particulate transition metals has little effect on the electrocardiograms of dogs having preexisting cardiac abnormalities. | INHALATION TOXICOLOGY | Muggenburg BA, Benson JM, Barr EB, Kubatko J, Tilley LP | Muggenburg BA, Benson JM, Barr EB, Kubatko J, Tilley LP. Short-term inhalation of particulate transition metals has little effect on the electrocardiograms of dogs having preexisting cardiac abnormalities. Inhalation Toxicology 2003;15(4):357-371. |
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Journal Article | Pulmonary immunity to ragweed in a Beagle dog model of allergic asthma. | EXPERIMENTAL LUNG RESEARCH | Redman TK, Rudolph K, Barr EB, Bowen LE, Muggenburg BA, Bice DE | Redman TK, Rudolph K, Barr EB, Bowen LE, Muggenburg BA, Bice DE. Pulmonary immunity to ragweed in a Beagle dog model of allergic asthma. Experimental Lung Research 2001;27(5):433-451. |
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Journal Article | Health effects of subchronic exposure to environmental levels of diesel exhaust. | INHALATION TOXICOLOGY | Reed MD, Gigliotti AP, McDonald JD, Seagrave JC, Seilkop SK, Mauderly JL | Reed MD, Gigliotti AP, McDonald JD, Seagrave JC, Seilkop SK, Mauderly JL. Health effects of subchronic exposure to environmental levels of diesel exhaust. Inhalation Toxicology 2004;16(4):177-193. |
CR831455 (Final) |
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Journal Article | Health effects of subchronic exposure to environmental levels of hardwood smoke. | INHALATION TOXICOLOGY | Reed MD, Campen MJ, Gigliotti AP, Harrod KS, McDonald JD, Seagrave JC, Mauderly JL, Seilkop SK | Reed MD, Campen MJ, Gigliotti AP, Harrod KS, McDonald JD, Seagrave JC, Mauderly JL, Seilkop SK. Health effects of subchronic exposure to environmental levels of hardwood smoke. Inhalation Toxicology 2006;18(8):523-539. |
CR831455 (2006) CR831455 (Final) |
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Journal Article | Health effects of subchronic inhalation exposure to gasoline engine exhaust. | INHALATION TOXICOLOGY | Reed M, Barrett EG, Campen MJ, Divine KK, Gigliotti AP, McDonald JD, Seagrave JC, Mauderly JL, Seilkop SK, Swenberg JA | Reed MD, Barrett EG, Campen MJ, Divine KK, Gigliotti AP, McDonald JD, Seagrave JC, Mauderly JL, Seilkop SK, Swenberg JA. Health effects of subchronic inhalation exposure to gasoline engine exhaust. Inhalation Toxicology 2008;20(13):1125-1143. |
CR831455 (Final) |
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Journal Article | Heart rate variability in rodents: uses and caveats in toxicological studies. | CARDIOVASCULAR TOXICOLOGY | Rowan WH, Campen MJ, Wichers LB, Watkinson WP | Rowan III WH, Campen MJ, Wichers LB, Watkinson WP. Heart rate variability in rodents: uses and caveats in toxicological studies. Cardiovascular Toxicology 2007;7(1):28-51. |
CR831455 (Final) R830839 (2005) R830839 (Final) |
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Journal Article | In vitro versus in vivo exposure to combustion emissions. | EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY | Seagrave J, McDonald JD, Mauderly JL | Seagrave J, McDonald JD, Mauderly JL. In vitro versus in vivo exposure to combustion emissions. Experimental and Toxicologic Pathology 2005;57(Suppl 1):233-238. |
CR831455 (2006) CR831455 (Final) |
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Journal Article | Responses to subchronic inhalation of low concentrations of diesel exhaust and hardwood smoke measured in rat bronchoalveolar lavage fluid. | INHALATION TOXICOLOGY | Seagrave J, McDonald JD, Reed MD, Seilkop SK, Mauderly JL | Seagrave J, McDonald JD, Reed MD, Seilkop SK, Mauderly JL. Responses to subchronic inhalation of low concentrations of diesel exhaust and hardwood smoke measured in rat bronchoalveolar lavage fluid. Inhalation Toxicology 2005;17(12):657-670. |
CR831455 (2004) CR831455 (2006) CR831455 (Final) |
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Journal Article | Responses of differentiated primary human lung epithelial cells to exposure to diesel exhaust at an air-liquid interface. | EXPERIMENTAL LUNG RESEARCH | Seagrave J, Dunaway S, McDonald JD, Mauderly JL, Hayden P, Stidley C | Seagrave J, Dunaway S, McDonald JD, Mauderly JL, Hayden P, Stidley C. Responses of differentiated primary human lung epithelial cells to exposure to diesel exhaust at an air-liquid interface. Experimental Lung Research 2007;33(1):27-51. |
CR831455 (Final) |
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Journal Article | Oxidative stress, inflammation and pulmonary function assessment in rats exposed to laboratory-generated pollutant mixtures. | Journal of Toxicology and Environmental Health Part A | Seagrave J, Campen MJ, McDonald JD, Mauderly JL, Rohr AC | Seagrave J, Campen MJ, McDonald JD, Mauderly JL, Rohr AC. Oxidative stress, inflammation, and pulmonary function assessment in rats exposed to laboratory-generated pollutant mixtures. Journal of Toxicology and Environmental Health, Part A 2008;71(20):1352-1362. |
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Journal Article | Effects of cigarette smoke exposure and cessation on inflammatory cells and matrix metalloproteinase activity in mice. | EXPERIMENTAL LUNG RESEARCH | Seagrave JC, Barr EB, March TH, Nikula KJ | Seagrave J, Barr EB, March TH, Nikula KJ. Effects of cigarette smoke exposure and cessation on inflammatory cells and matrix metalloproteinase activity in mice. Experimental Lung Research 2004;30(1):1-15. |
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Journal Article | Health effects of subchronic exposure to low levels of wood smoke in rats. | TOXICOLOGICAL SCIENCES | Tesfaigzi Y, Singh SP, Foster JE, Kubatko J, Barr EB, Fine PM, McDonald JD, Hahn FF, Mauderly JL | Tesfaigzi Y, Singh SP, Foster JE, Kubatko J, Barr EB, Fine PM, McDonald JD, Hahn FF, Mauderly JL. Health effects of subchronic exposure to low levels of wood smoke in rats. Toxicological Sciences 2002;65(1):115-125. |
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Journal Article | Low-level subchronic exposure to wood smoke exacerbates inflammatory responses in allergic rats. | TOXICOLOGICAL SCIENCES | Tesfaigzi Y, McDonald JD, Reed MD, Singh SP, De Sanctis G, Eynott PR, Hahn FF, Campen MJ, Mauderly JL | Tesfaigzi Y, McDonald JD, Reed MD, Singh SP, De Sanctis GT, Eynott PR, Hahn FF, Campen MJ, Mauderly JL. Low-level subchronic exposure to wood smoke exacerbates inflammatory responses in allergic rats. Toxicological Sciences 2005;88(2):505-513. |
CR831455 (2006) CR831455 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.