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Grantee Research Project Results

Final Report: Impacts of Climate Change on Health Benefits of a Tribal Alaskan Resource:Integrating Traditional Ecological Knowledge with Risk Assessment Through Local Monitoring

EPA Grant Number: R833707
Title: Impacts of Climate Change on Health Benefits of a Tribal Alaskan Resource:Integrating Traditional Ecological Knowledge with Risk Assessment Through Local Monitoring
Investigators: Lila, Mary Ann , Raskin, Ilya , Flint, Courtney , Johnson, Jennifer
Institution: University of Illinois Urbana-Champaign , Office of Alaska Native Health Research and Epidemiology , Rutgers
EPA Project Officer: Aja, Hayley
Project Period: January 1, 2008 through December 31, 2011
Project Amount: $300,000
RFA: Issues in Tribal Environmental Research and Health Promotion: Novel Approaches for Assessing and Managing Cumulative Risks and Impacts of Global Climate Change (2007) RFA Text |  Recipients Lists
Research Category: Environmental Justice , Climate Change , Tribal Environmental Health Research , Human Health

Objective:

To conduct parallel, integrated simultaneous research to:

1) provide baseline assessment of the bioactivity (health risk mitigation properties) of berry resources as influenced by climatic stress factors relevant to global climate change, via cross-comparison of three geographically triangulated tribal communities characterized by inherently different climatic regimes in Alaska, and,

2) assess local traditional knowledge and risk perceptions regarding community health, berries, and climate change, and integrate with biophysical findings for informed local health related decision-making. 

Summary/Accomplishments (Outputs/Outcomes):

Participatory research with community members in three Alaska communities (Akutan, Point Hope, and Seldovia) focused on the bioactive health properties of wild berries and their role in local knowledge and community practice. Screening of community berry resources demonstrated potent efficacy against Type II diabetes and obesity, as well as significant antimicrobial activity.  All berries contained the critical A-Type proanthocyanidins (phytochemicals) essential to this bioactive response, and usually deposited in response to environmental stressors.  Berry harvest and consumption were valued by communities both in terms of subsistence and nutrition, as well as a vehicle for social interaction and enjoyment of nature/the outdoors and family interaction.  Local communities noted strong apprehension about potential infringement on these valued resources by contamination, and possible climatic shifts.

Youth and adult community members from each site helped our graduate student and faculty project investigators to screen local berries for bioactive potential, using field deployable bioassay screens.  Promising candidates were selected for further laboratory study.  We conducted interviews and surveys with local residents about berries and broader community and environmental conditions. The wild Alaska berries studied were found to contain unique components and combinations of phytochemicals that are particularly effective at combating the ravages of metabolic syndrome (type II diabetes and obesity). Additionally, the components were potent antimicrobials.
 
The berries studied were found to all contain A-type proanthocyanidins as part of their phytochemical cocktail. This proanthocyanidin (tannin) configuration is relatively rare, found only in cranberries and blueberries among the commercially available berries. The significance of this unique component in the berries is that the A-type proanthocyanidin has anti-adhesin properties - that is, the berries, when eaten, will effectively disable the bacteria that cause urinary tract infection as well as the bacteria responsible for dental caries. That is, they are excellent natural therapies for these microbial diseases. The proanthocyanidin content in the berries also was highly effective at lowering lipid deposition into adipose tissue. In other words, berry components effectively prevent fat cell enlargement with implications for prevention of metabolic syndrome. The unique compliment of anthocyanins (pigments) in the berries proved to be particularly efficacious in reducing blood glucose levels in vivo, in a diabetic mouse model. That is, the consumption of the berries may prove to be an important deterrent to development of type II diabetes mellitus (T2DM) in adults. The discovery of these properties and the unique components that contribute to them all support the traditional use of the berries in local diets as a source not only of food, but also of medicines. Berries were found to play a key role in community wellness beyond nutrition due to social and outdoor activities associated with harvesting. These benefits, however, are potentially threatened by uncertain impacts from contamination, climate change, and socio-cultural and behavioral changes shifting focus away from locally available foods. Research findings are informing community wellness planning by the Alaska Native Tribal Health Consortium (ANTHC, http://www.anthc.org/chs/ces/index.cfm) and have served as important learning opportunities for community members, particularly youth.
 
Beyond Alaska, this transdisciplinary research informs diverse academic audiences regarding methodologies for integrated, participatory, socio-biological investigation in addition to expanding disciplinary lines of inquiry on bioactivity in wild plants, traditional ecological knowledge, and community natural resource sociology.
 
Several interviews resulted from this work:
  1. National Public Radio (NPR). The People’s Pharmacy, Joe & Terry Graedon, for NPR stations nationwide, broadcast Saturday June 25, 2011, 7:00-8:00 a.m. EDT and rebroadcast 26 June at 3:00 p.m. EDT. On wild berries and phytochemicals that protect health. NPR Shows Feature Dr. Mary Ann Lila, Plants for Human Health Institute, June 27, 2011. http://plantsforhumanhealth.ncsu.edu/2011/06/24/npr-show-features-dr-lila/.
  2. COSMOS (an Australia-based national journal on all things science), interview with free-lance reporter Jessica Wapner. “Where the wild berries grow” feature article w/photography. December 2011, www.cosmosmagazine.com/issues/2011/42/. 
  3. The Ecologist, interviewed by free-lance reporter Jessica Wapner, The struggle to save Alaska's 'illness-busting' wild berries, printed September 7, 2011.

Conclusions:

A strong sense of community and solidarity clearly centered on the annual wild berry yields in Alaska Native communities. Scouting, family-centered wildcrafting/harvests, and preparations were highly anticipated events. Wild berries conditioned human consumer susceptibility to T2DM and metabolic syndrome on multiple fronts (different effects for different species of berry), including elevation of gut enzymes, which inhibit adipogenesis, and prevention of lipid deposition into adipose tissue.  In other words, the research findings suggest that berry consumption has the ability to increase human satiety and counter development of central obesity. Community members’ perspectives about the impacts of climate change on this tradition varied, and often risks were categorized along with other perceived threats to the subsistence berries (e.g., pollution threats). 

This methods development project has been completed; however, we continue to work with colleagues at Alaska Native Tribal Health Consortium to find additional project funding to expand our work to the Juneau/Sitka area and to explore educational applications for the program’s toolkits.  A key impact of the project is the incorporation of some of the project’s participatory approaches and methods in current community health outreach work with ANTHC. 


Journal Articles on this Report : 1 Displayed | Download in RIS Format

Publications Views
Other project views: All 17 publications 5 publications in selected types All 5 journal articles
Publications
Type Citation Project Document Sources
Journal Article McOliver CA, Camper AK, Doyle JT, Eggers MJ, Ford TE, Lila MA, Berner J, Campbell L, Donatuto J. Community-based research as a mechanism to reduce environmental health disparities in American Indian and Alaska Native communities. International Journal of Environmental Research and Public Health 2015;12(4):4076-4100. R833707 (Final)
R833706 (Final)
R834791 (Final)
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  • Supplemental Keywords:

    biological activity, health and wellness, wild berries, tribes, tribal, subsistence, diabetes, obesity

    Relevant Websites:

    http://www.lilalab.com Exit

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    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

    Project Research Results

    • 2010 Progress Report
    • 2009 Progress Report
    • 2008
    • Original Abstract
    17 publications for this project
    5 journal articles for this project

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